PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 5YAX

#CDRs = 8; #Clusters = 9.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	heavy	Homo.sapiens	Hu_IGHV6-1*01	100.0	Hu_IGHV6-1*01	86.7	H1	15	H1-15-2	11	GISGDSVSSksAAWN	BBBLBBAABAABBBB
A	heavy	Homo.sapiens	Hu_IGHV6-1*01	100.0	Hu_IGHV6-1*01	90.9	H2	11	H2-11-1	9	RTYYRsKWHND	BBBBBLBBBBB
A	heavy	Homo.sapiens	Hu_IGHV6-1*01	100.0	Hu_IGHV6-1*01	100.0	H3	10	H3-10-1	13	ARGQMGALDV	BBBBLLBBAB
A	heavy	Homo.sapiens	Hu_IGHV6-1*01	100.0	Hu_IGHV6-1*01	100.0	H4	8	H4-8-1	19	PDTSKNQF	BBAAALBB
A	lambda	Homo.sapiens	Hu_IGLV1-40*01	95.6	CDRLenMismatch	-1.0	L1	13	L1-13-1	10	SGSSSNIGSYYVY	BBBAAAAAABBBB
A	lambda	Homo.sapiens	Hu_IGLV1-40*01	95.6	Hu_IGLV1-40*01	75.0	L2	8	L2-8-1	12	YGNNQRPS	BLEABBBB
A	lambda	Homo.sapiens	Hu_IGLV1-40*01	95.6	Hu_IGLV1-40*01	100.0	L3	11	L3-11-1	14	QSYDSSLSGVI	BBBBAAALBBB
A	lambda	Homo.sapiens	Hu_IGLV1-40*01	95.6	Hu_IGLV1-40*01	100.0	L4	6	L4-6-2	12	KSGTSA	BBEABB
B	heavy	Homo.sapiens	Hu_IGHV6-1*01	100.0	Hu_IGHV6-1*01	86.7	H1	15	H1-15-2	10	GISGDSVSSksAAWN	BBBLBBAABAABBBB
B	heavy	Homo.sapiens	Hu_IGHV6-1*01	100.0	Hu_IGHV6-1*01	90.9	H2	11	H2-11-1	8	RTYYRsKWHND	BBBBBLBBBBB
B	heavy	Homo.sapiens	Hu_IGHV6-1*01	100.0	Hu_IGHV6-1*01	100.0	H3	10	H3-10-*	-1	ARGQMGALDV	BBBAALBBAB
B	heavy	Homo.sapiens	Hu_IGHV6-1*01	100.0	Hu_IGHV6-1*01	100.0	H4	8	H4-8-1	20	PDTSKNQF	BBAAALBB
B	lambda	Homo.sapiens	Hu_IGLV1-40*01	95.6	CDRLenMismatch	-1.0	L1	13	L1-13-1	8	SGSSSNIGSYYVY	BBBAAAAAABBBB
B	lambda	Homo.sapiens	Hu_IGLV1-40*01	95.6	Hu_IGLV1-40*01	75.0	L2	8	L2-8-1	14	YGNNQRPS	BLEABBBB
B	lambda	Homo.sapiens	Hu_IGLV1-40*01	95.6	Hu_IGLV1-40*01	100.0	L3	11	L3-11-1	11	QSYDSSLSGVI	BBBBAAALBBB
B	lambda	Homo.sapiens	Hu_IGLV1-40*01	95.6	Hu_IGLV1-40*01	100.0	L4	6	L4-6-2	12	KSGTSA	BBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022