PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDR Structures for H2-11-1

Summary info for H2-11-1
Loop	# of Structures	% of Loop Length	Median PDB	Consensus Sequence	# of Unique Seq	% of Unique Seq	Gene	Loop Conformation	Median Angle	Consensus Sequence Logo
H2-11-1	29	22.66	2H_7O4YH	RTYYRSKwYND	11	22.00	heavy	BBBBBLBBBBB	7

Structures in cluster H2-11-1
Cluster	PDB	Resolution	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	Sequence	Ramachandran	Distance(°)
H2-11-1	5YAXA	2.5	heavy	Homo.sapiens	Hu_IGHV6-1*01	100.0	Hu_IGHV6-1*01	90.9	RTYYRsKWHND	BBBBBLBBBBB	9
H2-11-1	5YAXB	2.5	heavy	Homo.sapiens	Hu_IGHV6-1*01	100.0	Hu_IGHV6-1*01	90.9	RTYYRsKWHND	BBBBBLBBBBB	8
H2-11-1	3H0TB	1.89	heavy	Homo.sapiens	Hu_IGHV6-1*01	98.6	Hu_IGHV6-1*01	90.9	RTYYRSKwFND	BBBBBLBBBBB	7
H2-11-1	7EPUA	3.5	heavy	Homo.sapiens	Hu_IGHV6-1*01	93.2	Hu_IGHV6-1*01	81.8	RTYYRsKWSNE	BBBBBLBBBBB	14
H2-11-1	6WJ0H	1.802	heavy	Homo.sapiens	Hu_IGHV6-1*01	89.0	Hu_IGHV6-1*01	81.8	RTYfRSKWYTD	BBBBBLBBBBB	6
H2-11-1	6WJ1J	3.503	heavy	Homo.sapiens	Hu_IGHV6-1*01	89.0	Hu_IGHV6-1*01	81.8	RTYfRSKWYTD	BBBBBLBBBBB	7
H2-11-1	6WJ1G	3.503	heavy	Homo.sapiens	Hu_IGHV6-1*01	89.0	Hu_IGHV6-1*01	81.8	RTYfRSKWYTD	BBBBBLBBBBB	6
H2-11-1	6WJ1H	3.503	heavy	Homo.sapiens	Hu_IGHV6-1*01	89.0	Hu_IGHV6-1*01	81.8	RTYfRSKWYTD	BBBBBLBBBBB	5
H2-11-1	6WIYH	1.65	heavy	Homo.sapiens	Hu_IGHV6-1*01	93.2	Hu_IGHV6-1*01	90.9	RTYYRsKWYDD	BBBBBLBBBBB	6
H2-11-1	6WIZH	4.2	heavy	Homo.sapiens	Hu_IGHV6-1*01	93.2	Hu_IGHV6-1*01	90.9	RTYYRsKWYDD	BBBBBLBBBBB	9
H2-11-1	5K9JH	1.904	heavy	Homo.sapiens	Hu_IGHV6-1*01	95.9	Hu_IGHV6-1*01	90.9	RTYYrSKWYTD	BBBBBLBBBBB	7
H2-11-1	5K9KA	2.97	heavy	Homo.sapiens	Hu_IGHV6-1*01	95.9	Hu_IGHV6-1*01	90.9	RTYYrSKWYTD	BBBBBLBBBBB	8
H2-11-1	5K9KH	2.97	heavy	Homo.sapiens	Hu_IGHV6-1*01	95.9	Hu_IGHV6-1*01	90.9	RTYYrSKWYTD	BBBBBLBBBBB	6
H2-11-1	6GFEH	1.8	heavy	Homo.sapiens	Hu_IGHV6-1*01	95.9	Hu_IGHV6-1*01	72.7	RTYYRShWYYE	BBBBBLBBBBB	6
H2-11-1	6GFEK	1.8	heavy	Homo.sapiens	Hu_IGHV6-1*01	95.9	Hu_IGHV6-1*01	72.7	RTYYRShWYYE	BBBBBLBBBBB	7
H2-11-1	7O4YH	1.6	heavy	Homo.sapiens	Hu_IGHV6-1*01	100.0	Hu_IGHV6-1*01	100.0	RTYYRsKWYND	BBBBBLEBBBB	5
H2-11-1	5JW3H	3.75	heavy	Homo.sapiens	Hu_IGHV6-1*01	98.6	Hu_IGHV6-1*01	90.9	RTYYRSGwYND	BBBBBLEBBBB	13
H2-11-1	5JW4U	3.7	heavy	Homo.sapiens	Hu_IGHV6-1*01	98.6	Hu_IGHV6-1*01	90.9	RTYYRSGwYND	BBBBBLEBBBB	13
H2-11-1	5JW4Q	3.7	heavy	Homo.sapiens	Hu_IGHV6-1*01	98.6	Hu_IGHV6-1*01	90.9	RTYYRSGwYND	BBBBBLEBBBB	13
H2-11-1	7KC1J	EM	heavy	Homo.sapiens	Hu_IGHV6-1*01	90.4	Hu_IGHV6-1*01	72.7	RTfYRSKWYKE	BBBBBLBBBBB	11
H2-11-1	5JW4W	3.7	heavy	Homo.sapiens	Hu_IGHV6-1*01	98.6	Hu_IGHV6-1*01	90.9	RTYYRSGwYND	BBBBBLEBBBB	13
H2-11-1	5JW4M	3.7	heavy	Homo.sapiens	Hu_IGHV6-1*01	98.6	Hu_IGHV6-1*01	90.9	RTYYRSGwYND	BBBBBLEBBBB	13
H2-11-1	7KC1H	EM	heavy	Homo.sapiens	Hu_IGHV6-1*01	90.4	Hu_IGHV6-1*01	72.7	RTfYRSKWYKE	BBBBBLBBBBB	14
H2-11-1	5JW4S	3.7	heavy	Homo.sapiens	Hu_IGHV6-1*01	98.6	Hu_IGHV6-1*01	90.9	RTYYRSGwYND	BBBBBLEBBBB	13
H2-11-1	5JW4O	3.7	heavy	Homo.sapiens	Hu_IGHV6-1*01	98.6	Hu_IGHV6-1*01	90.9	RTYYRSGwYND	BBBBBLEBBBB	13
H2-11-1	6ZTFA	1.55	heavy	Homo.sapiens	Hu_IGHV6-1*01	98.6	Hu_IGHV6-1*01	90.9	RIYYRSKwYND	BBBBBLBBBBB	7
H2-11-1	6ZTFH	1.55	heavy	Homo.sapiens	Hu_IGHV6-1*01	98.6	Hu_IGHV6-1*01	90.9	RIYYRSKwYND	BBBBBLBBBBB	7
H2-11-1	5JW5H	1.9	heavy	Homo.sapiens	Hu_IGHV6-1*01	98.6	Hu_IGHV6-1*01	90.9	RTYYRSGwYND	BBBBBLEBBBB	13
H2-11-1	5JW5A	1.9	heavy	Homo.sapiens	Hu_IGHV6-1*01	98.6	Hu_IGHV6-1*01	90.9	RTYYRSGwYND	BBBBBLEBBBB	13

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022