PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDR Structures for H3-10-1

Summary info for H3-10-1
Loop	# of Structures	% of Loop Length	Median PDB	Consensus Sequence	# of Unique Seq	% of Unique Seq	Gene	Loop Conformation	Median Angle	Consensus Sequence Logo
H3-10-1	85	14.89	5H_1PG7H	ARdGyGaFDy	27	13.99	heavy	BBBBLLBBAB	13

Structures in cluster H3-10-1
Cluster	PDB	Resolution	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	Sequence	Ramachandran	Distance(°)
H3-10-1	1F4WH	2.3	heavy	Mus.musculus	Mo_IGHV5-12-1*01	93.2	Mo_IGHV5-12-1*01	50.0	TRHFYAVLDY	BBBBLLBBAB	16
H3-10-1	1F4XH	2.3	heavy	Mus.musculus	Mo_IGHV5-12-1*01	93.2	Mo_IGHV5-12-1*01	50.0	TRHFYAVLDY	BBBBLLBBAB	16
H3-10-1	1PG7I	2.5	heavy	Mus.musculus.Homo.sapiens	Hu_IGHV3-66*01	86.3	Hu_IGHV3-66*01	100.0	ARDTAAYFDY	BBBBLLBBAB	10
H3-10-1	1PG7H	2.5	heavy	Mus.musculus.Homo.sapiens	Hu_IGHV3-66*01	86.3	Hu_IGHV3-66*01	100.0	ARDTAAYFDY	BBBBLLBBAB	10
H3-10-1	4AMKH	2.05	heavy	Mus.musculus	Mo_IGHV1S121*01	98.3	Mo_IGHV1S121*01	0.0	SRGGAGIMAY	BBBELLBBAB	21
H3-10-1	5GKRA	2.1	heavy	Homo.sapiens	Hu_IGHV4-59*01	95.9	Hu_IGHV4-59*01	100.0	ARHRNWLFDY	BBBBLLBBAB	13
H3-10-1	5GKSA	2.05	heavy	Homo.sapiens	Hu_IGHV4-59*01	95.9	Hu_IGHV4-59*01	100.0	ARHRNWLFDY	BBBBLLBBAB	15
H3-10-1	5GKRC	2.1	heavy	Homo.sapiens	Hu_IGHV4-59*01	95.9	Hu_IGHV4-59*01	100.0	ARHRNWLFDY	BBBBLLBBAB	13
H3-10-1	5GKSC	2.05	heavy	Homo.sapiens	Hu_IGHV4-59*01	95.9	Hu_IGHV4-59*01	100.0	ARHRNWLFDY	BBBBLLBBAB	19
H3-10-1	6YAXHHH	2.8	heavy	Homo.sapiens	Hu_IGHV3-23*05	98.6	Hu_IGHV3-23*05	50.0	ARENFDAFDV	BBBBLLBBAB	10
H3-10-1	6YAXIII	2.8	heavy	Homo.sapiens	Hu_IGHV3-23*05	98.6	Hu_IGHV3-23*05	50.0	ARENFDAFDV	BBBBLLBBAB	11
H3-10-1	5YAXA	2.5	heavy	Homo.sapiens	Hu_IGHV6-1*01	100.0	Hu_IGHV6-1*01	100.0	ARGQMGALDV	BBBBLLBBAB	13
H3-10-1	7MZIH	1.85	heavy	Homo.sapiens	Hu_IGHV3-23*01	100.0	Hu_IGHV3-23*01	100.0	AKVGWGAFDI	BBBBLLBBAB	9
H3-10-1	7MZJC	2.4	heavy	Homo.sapiens	Hu_IGHV3-23*01	100.0	Hu_IGHV3-23*01	100.0	AKVGWGAFDI	BBBBLLBBAB	10
H3-10-1	7MZKF	2.25	heavy	Homo.sapiens	Hu_IGHV3-23*01	100.0	Hu_IGHV3-23*01	100.0	AKVGWGAFDI	BBBBLLBBAB	12
H3-10-1	7MZKC	2.25	heavy	Homo.sapiens	Hu_IGHV3-23*01	100.0	Hu_IGHV3-23*01	100.0	AKVGWGAFDI	BBBBLLBBAB	12
H3-10-1	7MZJF	2.4	heavy	Homo.sapiens	Hu_IGHV3-23*01	100.0	Hu_IGHV3-23*01	100.0	AKVGWGAFDI	BBBBLLBBAB	14
H3-10-1	4V1DA	3.1	heavy	Homo.sapiens	Hu_IGHV3-9*01	87.7	Hu_IGHV3-9*01	33.3	ARGGFGSFDT	BBBALLBBAB	25
H3-10-1	1A7QH	2	heavy	Mus.musculus	Mo_IGHV2-6-7*01	93.2	Mo_IGHV2-6-7*01	100.0	ARERDYRLDY	BBBBLLBBAB	16
H3-10-1	4BZ1H	2.15	heavy	Mus.musculus	Mo_IGHV1S75*01	96.7	Mo_IGHV1S75*01	0.0	SRGSKGAMDY	BBBBLLBBAB	18
H3-10-1	4LQFH	2.3	heavy	Mus.musculus	Mo_IGHV5-12*02	93.2	Mo_IGHV5-12*02	100.0	ARQWGGAMDY	BBBBLLBBAB	17
H3-10-1	3UO1H	1.641	heavy	Mus.musculus	Mo_IGHV5-16*01	94.5	Mo_IGHV5-16*01	100.0	ARLTNGYLDV	BBBBLLBBAB	10
H3-10-1	3UYRH	1.7	heavy	Mus.musculus	Mo_IGHV5-16*01	94.5	Mo_IGHV5-16*01	100.0	ARLTNGYLDV	BBBBLLBBAB	10
H3-10-1	3V4UH	1.64	heavy	Mus.musculus	Mo_IGHV5-16*01	94.5	Mo_IGHV5-16*01	100.0	ARLTNGYLDV	BBBBLLBBAB	10
H3-10-1	3V52H	1.697	heavy	Mus.musculus	Mo_IGHV5-16*01	94.5	Mo_IGHV5-16*01	100.0	ARLTNGYLDV	BBBBLLBBAB	9
H3-10-1	5YD3E	1.35	heavy	Mus.musculus	Mo_IGHV1-63*02	98.6	Mo_IGHV1-63*02	100.0	ARDYYTNYGD	BBBBLLBBAB	15
H3-10-1	5YD4E	1.35	heavy	Mus.musculus	Mo_IGHV1-63*02	98.6	Mo_IGHV1-63*02	100.0	ARDYYTNYGD	BBBBLLBBAB	15
H3-10-1	5YD3C	1.35	heavy	Mus.musculus	Mo_IGHV1-63*02	98.6	Mo_IGHV1-63*02	100.0	ARDYYTNYGD	BBBBLLBBAB	13
H3-10-1	5YD5A	1.96	heavy	Mus.musculus	Mo_IGHV1-63*02	98.6	Mo_IGHV1-63*02	100.0	ARDYYTNYGD	BBBBLLBBAB	14
H3-10-1	5YY4A	1.59	heavy	Mus.musculus	Mo_IGHV1-63*02	98.6	Mo_IGHV1-63*02	100.0	ARDYYTNYGD	BBBBLLBBAB	15
H3-10-1	5YD4C	1.35	heavy	Mus.musculus	Mo_IGHV1-63*02	98.6	Mo_IGHV1-63*02	100.0	ARDYYTNYGD	BBBBLLBBAB	14
H3-10-1	5YD3A	1.35	heavy	Mus.musculus	Mo_IGHV1-63*02	98.6	Mo_IGHV1-63*02	100.0	ARDYYTNYGD	BBBBLLBBAB	14
H3-10-1	5YD5C	1.96	heavy	Mus.musculus	Mo_IGHV1-63*02	98.6	Mo_IGHV1-63*02	100.0	ARDYYTNYGD	BBBBLLBBAB	15
H3-10-1	5YD4A	1.35	heavy	Mus.musculus	Mo_IGHV1-63*02	98.6	Mo_IGHV1-63*02	100.0	ARDYYTNYGD	BBBBLLBBAB	14
H3-10-1	5YD3G	1.35	heavy	Mus.musculus	Mo_IGHV1-63*02	98.6	Mo_IGHV1-63*02	100.0	ARDYYTNYGD	BBBBLLBBAB	22
H3-10-1	5YD4G	1.35	heavy	Mus.musculus	Mo_IGHV1-63*02	98.6	Mo_IGHV1-63*02	100.0	ARDYYTNYGD	BBBBLLBBAB	13
H3-10-1	7WKXA	2.81	heavy	Homo.sapiens	Hu_IGHV7-4-1*03	95.6	Hu_IGHV7-4-1*03	0.0	ANYGWGYFDY	BBBBLLBBAB	20
H3-10-1	7WKXB	2.81	heavy	Homo.sapiens	Hu_IGHV7-4-1*03	95.6	Hu_IGHV7-4-1*03	0.0	ANYGWGYFDY	BBBBLLBBAB	21
H3-10-1	4K9EH	2.7	heavy	Mus.musculus	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	100.0	ARYVYHALDY	BBBBLLBBAB	12
H3-10-1	7TXZE	EM	heavy	Mus.sp.	Mo_IGHV6-6*02	98.6	Mo_IGHV6-6*02	100.0	TRVITTVFAY	BBBBLLBBAB	14
H3-10-1	7TY0J	EM	heavy	Mus.musculus	Mo_IGHV6-6*02	98.6	Mo_IGHV6-6*02	100.0	TRVITTVFAY	BBBBLLBBAB	15
H3-10-1	7TY0K	EM	heavy	Mus.musculus	Mo_IGHV6-6*02	98.6	Mo_IGHV6-6*02	100.0	TRVITTVFAY	BBBBLLBBAB	13
H3-10-1	7TXZH	EM	heavy	Mus.sp.	Mo_IGHV6-6*02	98.6	Mo_IGHV6-6*02	100.0	TRVITTVFAY	BBBBLLBBAB	14
H3-10-1	4K94H	2.4	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	100.0	ARYVYHALDY	BBBBLLBBAB	14
H3-10-1	1A2YB	1.5	heavy	Mus.musculus	Mo_IGHV2-6-7*01	97.3	Mo_IGHV2-6-7*01	100.0	ARERDYRLDY	BBBBLLBBAB	11
H3-10-1	1A7NH	2.01	heavy	Mus.musculus	Mo_IGHV2-6-7*01	97.3	Mo_IGHV2-6-7*01	100.0	ARERDYRLDY	BBBBLLBBAB	17
H3-10-1	1A7OH	2	heavy	Mus.musculus	Mo_IGHV2-6-7*01	97.3	Mo_IGHV2-6-7*01	100.0	ARERDYRLDY	BBBBLLBBAB	15
H3-10-1	1A7PH	2.01	heavy	Mus.musculus	Mo_IGHV2-6-7*01	97.3	Mo_IGHV2-6-7*01	100.0	ARERDYRLDY	BBBBLLBBAB	15
H3-10-1	1A7RH	2.01	heavy	Mus.musculus	Mo_IGHV2-6-7*01	97.3	Mo_IGHV2-6-7*01	100.0	ARERDYRLDY	BBBBLLBBAB	14
H3-10-1	1BVKB	2.7	heavy	Homo.sapiens	Hu_IGHV4-59*04	87.7	Hu_IGHV4-59*04	100.0	ARERDYRLDY	BBBBLLBBAB	18
H3-10-1	1BVLA	2.87	heavy	Homo.sapiens.Mus.musculus	Hu_IGHV4-59*04	87.7	Hu_IGHV4-59*04	100.0	ARERDYRLDY	BBBBLLBBAB	9
H3-10-1	1BVKE	2.7	heavy	Homo.sapiens	Hu_IGHV4-59*04	87.7	Hu_IGHV4-59*04	100.0	ARERDYRLDY	BBBBLLBBAB	11
H3-10-1	1BVLC	2.87	heavy	Homo.sapiens.Mus.musculus	Hu_IGHV4-59*04	87.7	Hu_IGHV4-59*04	100.0	ARERDYRLDY	BBBBLLBBAB	13
H3-10-1	1CICD	2.5	heavy	Mus.musculus	Mo_IGHV2-6-7*01	98.6	Mo_IGHV2-6-7*01	100.0	ARERDYRLDY	BBBBLLBBAB	11
H3-10-1	1DVFB	1.9	heavy	Mus.musculus	Mo_IGHV2-6-7*01	97.3	Mo_IGHV2-6-7*01	100.0	ARERDYRLDY	BBBBLLBBAB	10
H3-10-1	1FDLH	2.5	heavy	Mus.musculus	Mo_IGHV2-6-7*01	98.6	Mo_IGHV2-6-7*01	100.0	ARERDYRLDY	BBBBLLBBAB	15
H3-10-1	1G7HB	1.85	heavy	Mus.musculus	Mo_IGHV2-6-7*01	97.3	Mo_IGHV2-6-7*01	100.0	ARERDYRLDY	BBBBLLBBAB	9
H3-10-1	1G7IB	1.8	heavy	Mus.musculus	Mo_IGHV2-6-7*01	97.3	Mo_IGHV2-6-7*01	100.0	ARERDYRLDY	BBBBLLBBAB	10
H3-10-1	1G7JB	1.75	heavy	Mus.musculus	Mo_IGHV2-6-7*01	97.3	Mo_IGHV2-6-7*01	100.0	ARERDYRLDY	BBBBLLBBAB	9
H3-10-1	1G7LB	2	heavy	Mus.musculus	Mo_IGHV2-6-7*01	97.3	Mo_IGHV2-6-7*01	100.0	ARERDYRLDY	BBBBLLBBAB	10
H3-10-1	1G7MB	1.9	heavy	Mus.musculus	Mo_IGHV2-6-7*01	97.3	Mo_IGHV2-6-7*01	100.0	ARERDYRLDY	BBBBLLBBAB	11
H3-10-1	1KIPB	2.1	heavy	Mus.musculus	Mo_IGHV2-6-7*01	97.3	Mo_IGHV2-6-7*01	100.0	ARERDYRLDY	BBBBLLBBAB	10
H3-10-1	1KIQB	1.85	heavy	Mus.musculus	Mo_IGHV2-6-7*01	97.3	Mo_IGHV2-6-7*01	100.0	ARERDFRLDY	BBBBLLBBAB	12
H3-10-1	1KIRB	2	heavy	Mus.musculus	Mo_IGHV2-6-7*01	97.3	Mo_IGHV2-6-7*01	100.0	ARERDYRLDY	BBBBLLBBAB	10
H3-10-1	1VFAB	1.8	heavy	Mus.musculus	Mo_IGHV2-6-7*01	97.3	Mo_IGHV2-6-7*01	100.0	ARERDYRLDY	BBBBLLBBAB	15
H3-10-1	1VFBB	1.8	heavy	Mus.musculus	Mo_IGHV2-6-7*01	97.3	Mo_IGHV2-6-7*01	100.0	ARERDYRLDY	BBBBLLBBAB	10
H3-10-1	2YBRG	2.55	heavy	Homo.sapiens	Hu_IGHV3-9*01	87.7	Hu_IGHV3-9*01	33.3	ARGGVGSFDT	BBBALLBBAB	25
H3-10-1	2YC1A	1.9	heavy	Homo.sapiens	Hu_IGHV3-9*01	87.7	Hu_IGHV3-9*01	33.3	ARGGVGSFDT	BBBALLBBAB	25
H3-10-1	2YBRA	2.55	heavy	Homo.sapiens	Hu_IGHV3-9*01	87.7	Hu_IGHV3-9*01	33.3	ARGGVGSFDT	BBBALLBBAB	26
H3-10-1	2YC1D	1.9	heavy	Homo.sapiens	Hu_IGHV3-9*01	87.7	Hu_IGHV3-9*01	33.3	ARGGVGSFDT	BBBALLBBAB	25
H3-10-1	2YBRD	2.55	heavy	Homo.sapiens	Hu_IGHV3-9*01	87.7	Hu_IGHV3-9*01	33.3	ARGGVGSFDT	BBBALEBBAB	26
H3-10-1	6I04C	3.1	heavy	Homo.sapiens	Hu_IGHV4-39*01	98.6	Hu_IGHV4-39*01	100.0	ARTIYDLFDI	BBBBLLBBAB	15
H3-10-1	6I04H	3.1	heavy	Homo.sapiens	Hu_IGHV4-39*01	98.6	Hu_IGHV4-39*01	100.0	ARTIYDLFDI	BBBBLLBBAB	15
H3-10-1	6R2SB	3.04	heavy	Homo.sapiens	Hu_IGHV4-39*01	95.9	Hu_IGHV4-39*01	100.0	ARDGTGALDL	BBBBLLBBAB	25
H3-10-1	2GHWB	2.3	heavy	Homo.sapiens	Hu_IGHV3-33*03	95.9	Hu_IGHV3-33*03	50.0	ARDRSYYLDY	BBBBLLBBAB	15
H3-10-1	2GHWD	2.3	heavy	Homo.sapiens	Hu_IGHV3-33*03	95.9	Hu_IGHV3-33*03	50.0	ARDRSYYLDY	BBBBLLBBAB	15
H3-10-1	6AVQH	EM	heavy	Mus.musculus	Mo_IGHV5-12-1*01	93.2	Mo_IGHV5-12-1*01	100.0	ARHNYGSFAY	BBBBLLBBAB	16
H3-10-1	6AVRH	EM	heavy	Mus.musculus	Mo_IGHV5-12-1*01	93.2	Mo_IGHV5-12-1*01	100.0	ARHNYGSFAY	BBBBLLBBAB	16
H3-10-1	6AVUH	EM	heavy	Mus.musculus	Mo_IGHV5-12-1*01	93.2	Mo_IGHV5-12-1*01	100.0	ARHNYGSFAY	BBBBLLBBAB	16
H3-10-1	6OSVH	1.34	heavy	Oryctolagus.cuniculus	Hu_IGHV3-48*03	94.4	Hu_IGHV3-48*03	100.0	ARDDRWSLNI	BBBBLLBBAB	14
H3-10-1	1G9EA	NMR	heavy	Lama.glama	La_IGHV1S3*01_VHH	90.4	La_IGHV1S3*01_VHH	50.0	GAGEGGTWDS	BBBBLLBBAB	26
H3-10-1	7B3OH	2	heavy	Homo.sapiens	Hu_IGHV3-66*01	97.3	Hu_IGHV3-66*01	100.0	ARDVADAFDI	BBBBLLBBAB	12
H3-10-1	7E88D	3.14	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Hu_IGHV3-66*01	100.0	ARDRGLVSDY	BBBBLLBBAB	19
H3-10-1	7E88A	3.14	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Hu_IGHV3-66*01	100.0	ARDRGLVSDY	BBBBLLBBAB	20
H3-10-1	7KMIA	1.73	heavy	Homo.sapiens	Hu_IGHV3-53*01	100.0	Hu_IGHV3-53*01	100.0	AREVAGTYDY	BBBBLLBBAB	7

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022