PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDR Structures for L3-8-4

Summary info for L3-8-4
Loop	# of Structures	% of Loop Length	Median PDB	Consensus Sequence	# of Unique Seq	% of Unique Seq	Gene	Loop Conformation	Median Angle	Consensus Sequence Logo
L3-8-4	53	7.75	2L_7CQDM	qQYDsSpT	19	9.36	kappa lambda	BBBAABBB	18

Structures in cluster L3-8-4
Cluster	PDB	Resolution	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	Sequence	Ramachandran	Distance(°)
L3-8-4	6TXZN	3.06	lambda	Homo.sapiens	Hu_IGLV2-11*01	100.0	Hu_IGLV2-11*01	0.0	SSYADSVV	BBAAABBB	24
L3-8-4	6TXZM	3.06	lambda	Homo.sapiens	Hu_IGLV2-11*01	100.0	Hu_IGLV2-11*01	0.0	SSYADSVV	BBAAABBB	24
L3-8-4	6TXZL	3.06	lambda	Homo.sapiens	Hu_IGLV2-11*01	100.0	Hu_IGLV2-11*01	0.0	SSYADSVV	BBAAABBB	24
L3-8-4	6TXZO	3.06	lambda	Homo.sapiens	Hu_IGLV2-11*01	100.0	Hu_IGLV2-11*01	0.0	SSYADSVV	BBAAABBB	25
L3-8-4	7Z0YL	2.95	lambda	Homo.sapiens	Hu_IGLV2-11*01	98.5	Hu_IGLV2-11*01	0.0	CSYAGSWV	BBBAABBB	17
L3-8-4	6A4KN	3.15	lambda	Homo.sapiens	Hu_IGLV4-69*01	89.7	Hu_IGLV4-69*01	57.1	QTWDAGMV	BBBBABBB	17
L3-8-4	6JP7L	1.909	lambda	Homo.sapiens	Hu_IGLV4-69*01	89.7	Hu_IGLV4-69*01	57.1	QTWDAGMV	BBBBABBB	17
L3-8-4	6A4KM	3.15	lambda	Homo.sapiens	Hu_IGLV4-69*01	89.7	Hu_IGLV4-69*01	57.1	QTWDAGMV	BBBAABBB	14
L3-8-4	6A4KL	3.15	lambda	Homo.sapiens	Hu_IGLV4-69*01	89.7	Hu_IGLV4-69*01	57.1	QTWDAGMV	BBBBABBB	17
L3-8-4	6A4KO	3.15	lambda	Homo.sapiens	Hu_IGLV4-69*01	89.7	Hu_IGLV4-69*01	57.1	QTWDAGMV	BBBBABBB	17
L3-8-4	4YO0B	1.56	lambda	Rattus.norvegicus	Ra_IGLV3S2*01	100.0	Ra_IGLV3S2*01	75.0	HSYSSGIV	BBBBABBB	18
L3-8-4	5XCVB	2.143	lambda	Homo.sapiens	Ra_IGLV3S2*01	100.0	Ra_IGLV3S2*01	75.0	HSYSSGIV	BBBBABBB	19
L3-8-4	4YO0D	1.56	lambda	Rattus.norvegicus	Ra_IGLV3S2*01	100.0	Ra_IGLV3S2*01	75.0	HSYSSGIV	BBBBABBB	20
L3-8-4	5XCVE	2.143	lambda	Homo.sapiens	Ra_IGLV3S2*01	100.0	Ra_IGLV3S2*01	75.0	HSYSSGIV	BBBAABBB	19
L3-8-4	7CQCL	2.5	lambda	Rattus.norvegicus	Ra_IGLV3S2*01	100.0	Ra_IGLV3S2*01	75.0	HSYSSGIV	BBBBABBB	24
L3-8-4	7CQDL	3.2	lambda	Rattus.norvegicus	Ra_IGLV3S2*01	100.0	Ra_IGLV3S2*01	75.0	HSYSSGIV	BBBBABBB	18
L3-8-4	7CQDM	3.2	lambda	Rattus.norvegicus	Ra_IGLV3S2*01	100.0	Ra_IGLV3S2*01	75.0	HSYSSGIV	BBBBABBB	18
L3-8-4	6AL0L	2.6	lambda	Rattus.norvegicus	Ra_IGLV3S2*01	100.0	Ra_IGLV3S2*01	75.0	HSYSSGIV	BBBAABBB	21
L3-8-4	6AL1L	3.2	lambda	Rattus.norvegicus	Ra_IGLV3S2*01	100.0	Ra_IGLV3S2*01	75.0	HSYSSGIV	BBBAABBB	23
L3-8-4	6ICCL	2	lambda	Rattus.norvegicus	Ra_IGLV3S2*01	100.0	Ra_IGLV3S2*01	75.0	HSYSSGIV	BBBAABBB	22
L3-8-4	6ICFL	4	lambda	Rattus.norvegicus	Ra_IGLV3S2*01	100.0	Ra_IGLV3S2*01	75.0	HSYSSGIV	BBBAABBB	21
L3-8-4	5FHCB	6.704	lambda	Homo.sapiens	Hu_IGLV3-1*01	86.4	Hu_IGLV3-1*01	50.0	QTWDSTVV	BBBBABBB	12
L3-8-4	2A0LE	3.9	kappa	Mus.musculus	Mo_IGKV4-74*01	98.6	Mo_IGKV4-74*01	62.5	HQFHRSLT	BBBAABBB	21
L3-8-4	6PHGB	2	kappa	Homo.sapiens	Hu_IGKV2-28*01	100.0	Hu_IGKV2-28*01	100.0	MQALQTPT	BBBBABBB	34
L3-8-4	7NX6B	2.25	kappa	Homo.sapiens	Hu_IGKV3-20*02	92.8	Hu_IGKV3-20*02	100.0	QHYDTSPR	BBBAABBB	8
L3-8-4	7NX7B	2.3	kappa	Homo.sapiens	Hu_IGKV3-20*02	92.8	Hu_IGKV3-20*02	100.0	QHYDTSPR	BBBAABBB	13
L3-8-4	7NX8B	1.95	kappa	Homo.sapiens	Hu_IGKV3-20*02	92.8	Hu_IGKV3-20*02	100.0	QHYDTSPR	BBBAABBB	12
L3-8-4	7NX9B	2.4	kappa	Homo.sapiens	Hu_IGKV3-20*02	92.8	Hu_IGKV3-20*02	100.0	QHYDTSPR	BBBAABBB	9
L3-8-4	7NXAB	2.5	kappa	Homo.sapiens	Hu_IGKV3-20*02	92.8	Hu_IGKV3-20*02	100.0	QHYDTSPR	BBBAABBB	12
L3-8-4	7OR9B	2.34	kappa	Homo.sapiens	Hu_IGKV3-20*02	92.8	Hu_IGKV3-20*02	100.0	QHYDTSPR	BBBAABBB	12
L3-8-4	7NXBB	2.67	kappa	Homo.sapiens	Hu_IGKV3-20*02	92.8	Hu_IGKV3-20*02	100.0	QHYDTSPR	BBBAABBB	12
L3-8-4	7Q9GF	EM	kappa	Homo.sapiens	Hu_IGKV3-20*02	92.8	Hu_IGKV3-20*02	100.0	QHYDTSPR	BBBAABBB	18
L3-8-4	7Q9GL	EM	kappa	Homo.sapiens	Hu_IGKV3-20*02	92.8	Hu_IGKV3-20*02	100.0	QHYDTSPR	BBBAABBB	18
L3-8-4	7SWOL	EM	kappa	Homo.sapiens	Hu_IGKV3-20*01	98.6	Hu_IGKV3-20*01	85.7	QHYGSSPT	BBBBABBB	35
L3-8-4	1ORSA	1.9	kappa	Mus.musculus	Mo_IGKV4-74*01	98.6	Mo_IGKV4-74*01	62.5	HQFHRSLT	BBBAABBB	11
L3-8-4	3W9DB	2.32	kappa	Homo.sapiens	Hu_IGKV3-20*01	100.0	Hu_IGKV3-20*01	100.0	QQYGSSPT	BBABABBB	37
L3-8-4	3W9EB	2.3	kappa	Homo.sapiens	Hu_IGKV3-20*01	100.0	Hu_IGKV3-20*01	100.0	QQYGSSPT	BBABABBB	36
L3-8-4	3W9DD	2.32	kappa	Homo.sapiens	Hu_IGKV3-20*01	100.0	Hu_IGKV3-20*01	100.0	QQYGSSPT	BBABABBB	39
L3-8-4	7CDIL	2.96	kappa	Homo.sapiens	Hu_IGKV3-20*01	100.0	Hu_IGKV3-20*01	100.0	QQYGSSPT	BBBBABBB	14
L3-8-4	7E8ML	2.09	kappa	Homo.sapiens	Hu_IGKV3-20*01	98.6	Hu_IGKV3-20*01	100.0	QQYGSSPT	BBBAABBB	16
L3-8-4	7PS1B	2.4	kappa	Homo.sapiens	Hu_IGKV3-20*01	92.8	Hu_IGKV3-20*01	100.0	QQYGSSPL	BBBBABBB	19
L3-8-4	7ZXUL	1.89	kappa	Homo.sapiens	Hu_IGKV3-20*01	92.8	Hu_IGKV3-20*01	100.0	QQYGSSPL	BBBBABBB	20
L3-8-4	1BQLL	2.6	kappa	Mus.musculus	Mo_IGKV4-59*01	95.7	Mo_IGKV4-59*01	62.5	QQWGRNPT	BBBBABBB	34
L3-8-4	1YQVL	1.7	kappa	Mus.musculus	Mo_IGKV4-59*01	95.7	Mo_IGKV4-59*01	62.5	QQWGRNPT	BBBBABBB	36
L3-8-4	2IFFL	2.65	kappa	Mus.musculus	Mo_IGKV4-59*01	95.7	Mo_IGKV4-59*01	62.5	QQWGRNPT	BBBBABBB	33
L3-8-4	6LHPL	EM	kappa	Mus.musculus	Mo_IGKV13-85*01	97.1	Mo_IGKV13-85*01	100.0	QQYWSTPT	BBBAABBB	23
L3-8-4	6LKTB	1.8	kappa	Mus.musculus	Mo_IGKV4-70*01	94.2	Mo_IGKV4-70*01	71.4	HQRSRYHT	BBBAABBB	9
L3-8-4	6UVOL	2.9	kappa	Homo.sapiens	Hu_IGKV3-15*01	97.1	Hu_IGKV3-15*01	100.0	QQYNNWPL	BBAAABBB	34
L3-8-4	7T8WL	3.1	kappa	Homo.sapiens	Hu_IGKV3-15*01	97.1	Hu_IGKV3-15*01	100.0	QQYNNWPL	BBAAABBB	34
L3-8-4	5NMVL	1.65	kappa	Mus.musculus	Mo_IGKV6-13*01	94.1	Mo_IGKV6-13*01	85.7	QQYTSYPT	BBBAABBB	17
L3-8-4	7MZLL	3.7	kappa	Homo.sapiens	Hu_IGKV3-11*01	91.0	Hu_IGKV3-11*01	85.7	QQRSNWLT	BBAAABBB	31
L3-8-4	6P50L	2.9	kappa	Mus.musculus	Mo_IGKV19-93*01	98.6	Mo_IGKV19-93*01	100.0	LQYDNLLT	BBBAABBB	33
L3-8-4	4IRZL	2.84	kappa	Homo.sapiens	Hu_IGKV1-33*01	92.8	Hu_IGKV1-33*01	71.4	LQYDNLWT	BBBAABBB	28

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022