PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDR Structures for L1-8-1

Summary info for L1-8-1
Loop	# of Structures	% of Loop Length	Median PDB	Consensus Sequence	# of Unique Seq	% of Unique Seq	Gene	Loop Conformation	Median Angle	Consensus Sequence Logo
L1-8-1	23	54.76	1L_7A0YD	SGSsYNYG	9	50.00	lambda	BLBABBBB	12

Structures in cluster L1-8-1
Cluster	PDB	Resolution	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	Sequence	Ramachandran	Distance(°)
L1-8-1	4P49A	1.4	lambda	Gallus.gallus	Ch_IGLV1-1*02	93.9	Ch_IGLV1-1*02	50.0	SGSSGSYG	BLBABBBB	19
L1-8-1	6NMTA	1.83	lambda	Homo.sapiens	Ch_IGLV1-1*02	83.3	Ch_IGLV1-1*02	62.5	SGSRGRYG	BLBABBBB	11
L1-8-1	6NMVL	2.61	lambda	Homo.sapiens	Hu_IGLV3-25*02	71.2	CDRLenMismatch	-1.0	FGSSGNYG	BLBABBBB	13
L1-8-1	7A0WD	2.04	lambda	Gallus.gallus	Ch_IGLV1S1*01	90.9	Ch_IGLV1S1*01	50.0	SGGTYSYG	BLBABBBB	12
L1-8-1	7A0XD	2.37	lambda	Gallus.gallus	Ch_IGLV1S1*01	90.9	Ch_IGLV1S1*01	50.0	SGGTYSYG	BLBABBBB	11
L1-8-1	7A0WF	2.04	lambda	Gallus.gallus	Ch_IGLV1S1*01	90.9	Ch_IGLV1S1*01	50.0	SGGTYSYG	BLBABBBB	12
L1-8-1	7A0YD	2.45	lambda	Gallus.gallus	Ch_IGLV1S1*01	90.9	Ch_IGLV1S1*01	50.0	SGGTYSYG	BLBABBBB	11
L1-8-1	7A0XF	2.37	lambda	Gallus.gallus	Ch_IGLV1S1*01	90.9	Ch_IGLV1S1*01	50.0	SGGTYSYG	BLBABBBB	12
L1-8-1	7A0YF	2.45	lambda	Gallus.gallus	Ch_IGLV1S1*01	90.9	Ch_IGLV1S1*01	50.0	SGGTYSYG	BLBABBBB	12
L1-8-1	7PHWC	2.793	lambda	Gallus.gallus	Ch_IGLV1-1*02	95.5	Ch_IGLV1-1*02	50.0	SGSTYNYG	BLBABBBB	10
L1-8-1	7PHWF	2.793	lambda	Gallus.gallus	Ch_IGLV1-1*02	95.5	Ch_IGLV1-1*02	50.0	SGSTYNYG	BLBABBBB	10
L1-8-1	7PI3b	3.269	lambda	Gallus.gallus	Ch_IGLV1-1*02	95.5	Ch_IGLV1-1*02	50.0	SGSTYNYG	BLBABBBB	13
L1-8-1	7PI3N	3.269	lambda	Gallus.gallus	Ch_IGLV1-1*02	95.5	Ch_IGLV1-1*02	50.0	SGSTYNYG	BLBABBBB	17
L1-8-1	7PI3U	3.269	lambda	Gallus.gallus	Ch_IGLV1-1*02	95.5	Ch_IGLV1-1*02	50.0	SGSTYNYG	BLBABBBB	17
L1-8-1	7PI3G	3.269	lambda	Gallus.gallus	Ch_IGLV1-1*02	95.5	Ch_IGLV1-1*02	50.0	SGSTYNYG	BLBABBBB	17
L1-8-1	4LSUL	2.3	lambda	Homo.sapiens	Hu_IGLV2-14*02	76.5	CDRLenMismatch	-1.0	TGASTSVA	BLBABBBB	18
L1-8-1	6OZ2L	2.55	lambda	Homo.sapiens	Hu_IGLV2-18*02	82.4	CDRLenMismatch	-1.0	TGTHNYVS	BLBABBBB	19
L1-8-1	4GLRI	1.9	lambda	Gallus.gallus	Ch_IGLV1-1*02	86.8	Ch_IGLV1-1*02	50.0	SGSDYDYG	BLBABBBB	8
L1-8-1	4GLRK	1.9	lambda	Gallus.gallus	Ch_IGLV1-1*02	86.8	Ch_IGLV1-1*02	50.0	SGSDYDYG	BLBABBBB	8
L1-8-1	4JAMB	1.65	lambda	Homo.sapiens	Hu_IGLV3-1*01	86.4	CDRLenMismatch	-1.0	SGASTNVC	BLBABBBB	13
L1-8-1	4JANB	3.15	lambda	Homo.sapiens	Hu_IGLV3-1*01	86.4	CDRLenMismatch	-1.0	SGASTNVC	BLBABBBB	17
L1-8-1	4JAML	1.65	lambda	Homo.sapiens	Hu_IGLV3-1*01	86.4	CDRLenMismatch	-1.0	SGASTNVC	BLBABBBB	14
L1-8-1	4JANL	3.15	lambda	Homo.sapiens	Hu_IGLV3-1*01	86.4	CDRLenMismatch	-1.0	SGASTNVC	BLBABBBB	17

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022