PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDR Structures for H4-6-1

Summary info for H4-6-1
Loop	# of Structures	% of Loop Length	Median PDB	Consensus Sequence	# of Unique Seq	% of Unique Seq	Gene	Loop Conformation	Median Angle	Consensus Sequence Logo
H4-6-1	76	82.61	5H_6BA5B	KTSTTV	9	60.00	heavy	BBAABB	8

Structures in cluster H4-6-1
Cluster	PDB	Resolution	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	Sequence	Ramachandran	Distance(°)
H4-6-1	5C0NC	3	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	97.1	Rb_IGHV1S69*01	83.3	KASTTV	BBAABB	17
H4-6-1	5C0NH	3	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	97.1	Rb_IGHV1S69*01	83.3	KASTTV	BBAABB	16
H4-6-1	6LDWH	1.6	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	98.5	Rb_IGHV1S69*01	100.0	KTSTTV	BBAABB	8
H4-6-1	6LDWB	1.6	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	98.5	Rb_IGHV1S69*01	100.0	KTSTTV	BBAABB	8
H4-6-1	6X1UA	1.641	heavy	Oryctolagus.cuniculus	Rb_IGHV1S17*01	83.6	Rb_IGHV1S17*01	66.7	RTSTTV	BBAABB	8
H4-6-1	6X1UH	1.641	heavy	Oryctolagus.cuniculus	Rb_IGHV1S17*01	83.6	Rb_IGHV1S17*01	66.7	RTSTTV	BBAABB	8
H4-6-1	7D9ZH	1.123	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	100.0	Rb_IGHV1S69*01	100.0	KTSTTV	BBAABB	8
H4-6-1	7DAAH	2.51	heavy	Homo.sapiens	Rb_IGHV1S69*01	100.0	Rb_IGHV1S69*01	100.0	KTSTTV	BBAABB	10
H4-6-1	4HBCH	1.54	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	95.6	Rb_IGHV1S69*01	100.0	KTSTTV	BBAABB	7
H4-6-1	5I8KH	1.771	heavy	Homo.sapiens	Rb_IGHV1S69*01	85.7	Rb_IGHV1S69*01	83.3	RTSTTV	BBAABB	7
H4-6-1	6LDYA	1.77	heavy	Oryctolagus.cuniculus	Rb_IGHV1S17*01	97.0	Rb_IGHV1S17*01	100.0	KTSTTM	BBAABB	8
H4-6-1	6LDYH	1.77	heavy	Oryctolagus.cuniculus	Rb_IGHV1S17*01	97.0	Rb_IGHV1S17*01	100.0	KTSTTM	BBAABB	9
H4-6-1	5DHVA	2.3	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	87.1	Rb_IGHV1S69*01	83.3	DTSTTV	BBAABB	15
H4-6-1	5DHVH	2.3	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	87.1	Rb_IGHV1S69*01	83.3	DTSTTV	BBAABB	15
H4-6-1	5DHXB	2.9	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	87.1	Rb_IGHV1S69*01	83.3	DTSTTV	BBAABB	19
H4-6-1	5DHYA	3.1	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	87.1	Rb_IGHV1S69*01	83.3	DTSTTV	BBAABB	14
H4-6-1	5DHXL	2.9	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	87.1	Rb_IGHV1S69*01	83.3	DTSTTV	BBAABB	20
H4-6-1	5DHYH	3.1	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	87.1	Rb_IGHV1S69*01	83.3	DTSTTV	BBAABB	14
H4-6-1	5DHZH	4.3	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	87.1	Rb_IGHV1S69*01	83.3	DTSTTV	BBAABB	15
H4-6-1	6BA5D	1.62	heavy	Homo.sapiens	Rb_IGHV1S69*01	83.8	Rb_IGHV1S69*01	83.3	RTSTTV	BBAABB	4
H4-6-1	6BA5B	1.62	heavy	Homo.sapiens	Rb_IGHV1S69*01	83.8	Rb_IGHV1S69*01	83.3	RTSTTV	BBAABB	3
H4-6-1	6BAND	1.95	heavy	Homo.sapiens	Rb_IGHV1S69*01	83.8	Rb_IGHV1S69*01	83.3	RTSTTV	BBAABB	5
H4-6-1	6BANB	1.95	heavy	Homo.sapiens	Rb_IGHV1S69*01	83.8	Rb_IGHV1S69*01	83.3	RTSTTV	BBAABB	6
H4-6-1	6CF2A	3	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	87.1	Rb_IGHV1S69*01	83.3	DTSTTV	BBAABB	15
H4-6-1	6BA5F	1.62	heavy	Homo.sapiens	Rb_IGHV1S69*01	83.8	Rb_IGHV1S69*01	83.3	RTSTTV	BBAABB	3
H4-6-1	6CWTA	3.151	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	91.2	Rb_IGHV1S69*01	83.3	RTSTTV	BBAABB	11
H4-6-1	6BANF	1.95	heavy	Homo.sapiens	Rb_IGHV1S69*01	83.8	Rb_IGHV1S69*01	83.3	RTSTTV	BBAABB	5
H4-6-1	6BA5H	1.62	heavy	Homo.sapiens	Rb_IGHV1S69*01	83.8	Rb_IGHV1S69*01	83.3	RTSTTV	BBAABB	4
H4-6-1	6BANH	1.95	heavy	Homo.sapiens	Rb_IGHV1S69*01	83.8	Rb_IGHV1S69*01	83.3	RTSTTV	BBAABB	6
H4-6-1	6CWTC	3.151	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	91.2	Rb_IGHV1S69*01	83.3	RTSTTV	BBAABB	12
H4-6-1	5DS8A	1.95	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	98.5	Rb_IGHV1S69*01	100.0	KTSTTV	BBAABB	6
H4-6-1	5DS8H	1.95	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	98.5	Rb_IGHV1S69*01	100.0	KTSTTV	BBAABB	5
H4-6-1	5DUBA	2	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	98.5	Rb_IGHV1S69*01	100.0	KTSTTV	BBAABB	7
H4-6-1	6CVKB	2.38	heavy	Oryctolagus.cuniculus	Rb_IGHV1S44*01	83.1	Rb_IGHV1S44*01	0.0	KTSTTV	BBAABB	5
H4-6-1	5DUBH	2	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	98.5	Rb_IGHV1S69*01	100.0	KTSTTV	BBAABB	6
H4-6-1	6CVKA	2.38	heavy	Oryctolagus.cuniculus	Rb_IGHV1S44*01	83.1	Rb_IGHV1S44*01	0.0	KTSTTV	BBAABB	7
H4-6-1	6CWDB	3.33	heavy	Oryctolagus.cuniculus	Rb_IGHV1S44*01	83.1	Rb_IGHV1S44*01	0.0	KTSTTV	BBAABB	11
H4-6-1	6CWDA	3.33	heavy	Oryctolagus.cuniculus	Rb_IGHV1S44*01	83.1	Rb_IGHV1S44*01	0.0	KTSTTV	BBAABB	10
H4-6-1	6PILA	2.2	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	95.6	Rb_IGHV1S69*01	100.0	KTSTTV	BBAABB	13
H4-6-1	6CWDE	3.33	heavy	Oryctolagus.cuniculus	Rb_IGHV1S44*01	83.1	Rb_IGHV1S44*01	0.0	KTSTTV	BBAABB	11
H4-6-1	6PK8C	2.91	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	95.6	Rb_IGHV1S69*01	100.0	KTSTTV	BBAABB	7
H4-6-1	6CWDG	3.33	heavy	Oryctolagus.cuniculus	Rb_IGHV1S44*01	83.1	Rb_IGHV1S44*01	0.0	KTSTTV	BBAABB	12
H4-6-1	6PK8B	2.91	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	95.6	Rb_IGHV1S69*01	100.0	KTSTTV	BBAABB	8
H4-6-1	6PSCC	3.6	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	95.6	Rb_IGHV1S69*01	100.0	KTSTTV	BBAABB	9
H4-6-1	6PK8A	2.91	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	95.6	Rb_IGHV1S69*01	100.0	KTSTTV	BBAABB	8
H4-6-1	6PSCA	3.6	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	95.6	Rb_IGHV1S69*01	100.0	KTSTTV	BBAABB	8
H4-6-1	6PSCB	3.6	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	95.6	Rb_IGHV1S69*01	100.0	KTSTTV	BBAABB	8
H4-6-1	6PK8D	2.91	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	95.6	Rb_IGHV1S69*01	100.0	KTSTTV	BBAABB	9
H4-6-1	6LDVH	1.9	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	89.7	Rb_IGHV1S69*01	83.3	KTSTTI	BBAABB	5
H4-6-1	6I9IA	1.98	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	94.1	Rb_IGHV1S69*01	100.0	KTSTTV	BBAABB	6
H4-6-1	6I9IH	1.98	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	94.1	Rb_IGHV1S69*01	100.0	KTSTTV	BBAABB	6
H4-6-1	5DRNA	1.994	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	90.0	Rb_IGHV1S69*01	83.3	RTSTTV	BBAABB	9
H4-6-1	5DSCE	2.4	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	90.0	Rb_IGHV1S69*01	83.3	RTSTTV	BBAABB	8
H4-6-1	5DRNH	1.994	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	90.0	Rb_IGHV1S69*01	83.3	RTSTTV	BBAABB	10
H4-6-1	5DMGH	2.5	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	94.1	Rb_IGHV1S69*01	83.3	KASTTV	BBAABB	8
H4-6-1	5DSCC	2.4	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	90.0	Rb_IGHV1S69*01	83.3	RTSTTV	BBAABB	9
H4-6-1	6LDXH	1.8	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	91.3	Rb_IGHV1S69*01	83.3	KTSTTI	BBAABB	8
H4-6-1	5DMGC	2.5	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	94.1	Rb_IGHV1S69*01	83.3	KASTTV	BBAABB	10
H4-6-1	5DSCA	2.4	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	90.0	Rb_IGHV1S69*01	83.3	RTSTTV	BBAABB	9
H4-6-1	5DMGE	2.5	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	94.1	Rb_IGHV1S69*01	83.3	KASTTV	BBAABB	11
H4-6-1	5DSCH	2.4	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	90.0	Rb_IGHV1S69*01	83.3	RTSTTV	BBAABB	9
H4-6-1	7CN2J	EM	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	94.1	Rb_IGHV1S69*01	100.0	KTSTTV	BBAABB	15
H4-6-1	7O9SH	2.7	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	95.7	Rb_IGHV1S69*01	83.3	RTSTTV	BBAABB	5
H4-6-1	7CN2H	EM	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	94.1	Rb_IGHV1S69*01	100.0	KTSTTV	BBAABB	15
H4-6-1	7CN2I	EM	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	94.1	Rb_IGHV1S69*01	100.0	KTSTTV	BBAABB	15
H4-6-1	7CN2K	EM	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	94.1	Rb_IGHV1S69*01	100.0	KTSTTV	BBAABB	15
H4-6-1	7CN2M	EM	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	94.1	Rb_IGHV1S69*01	100.0	KTSTTV	BBAABB	15
H4-6-1	7CN2G	EM	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	94.1	Rb_IGHV1S69*01	100.0	KTSTTV	BBAABB	15
H4-6-1	7MFRY	2.848	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	95.6	Rb_IGHV1S69*01	100.0	KTSTTV	BBAABB	22
H4-6-1	7FBIN	EM	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	91.2	Rb_IGHV1S69*01	83.3	RTSTTV	BBAABB	15
H4-6-1	6WO3H	2.382	heavy	Homo.sapiens	Hu_IGHV1-69*01	80.0	Hu_IGHV1-69*01	0.0	ADEDTV	BBAABB	13
H4-6-1	7DCEH	EM	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	100.0	Rb_IGHV1S69*01	100.0	KTSTTV	BBAABB	9
H4-6-1	7NBBD	1.55	heavy	Synthetic.construct	Al_IGHV3S53*01_VHH	90.4	Al_IGHV3S53*01_VHH	0.0	RDNDTV	BBAABB	12
H4-6-1	7NBBH	1.55	heavy	Synthetic.construct	Al_IGHV3S53*01_VHH	90.4	Al_IGHV3S53*01_VHH	0.0	RDNDTV	BBAABB	10
H4-6-1	7MLHC	2.1	heavy	Homo.sapiens	Hu_IGHV1-69*01	95.9	Hu_IGHV1-69*01	0.0	ADESSA	BBAABB	14
H4-6-1	7MLHE	2.1	heavy	Homo.sapiens	Hu_IGHV1-69*01	95.9	Hu_IGHV1-69*01	0.0	ADESSA	BBAABB	13

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022