PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDR Structures for H3-7-1

Summary info for H3-7-1
Loop	# of Structures	% of Loop Length	Median PDB	Consensus Sequence	# of Unique Seq	% of Unique Seq	Gene	Loop Conformation	Median Angle	Consensus Sequence Logo
H3-7-1	74	33.33	2H_2DQCH	ARwdGDY	14	23.73	heavy	BBAALAB	7

Structures in cluster H3-7-1
Cluster	PDB	Resolution	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	Sequence	Ramachandran	Distance(°)
H3-7-1	1P4BH	2.35	heavy	Mus.musculus	Mo_IGHV2-6-7*01	88.9	Mo_IGHV2-6-7*01	0.0	VTGLFDY	BBAALAB	19
H3-7-1	6K65H	1.65	heavy	Mus.musculus	Mo_IGHV2-6-7*01	88.9	Mo_IGHV2-6-7*01	0.0	VTGLFDY	BBAALAB	18
H3-7-1	2ZNWA	2.71	heavy	Synthetic.construct	Mo_IGHV3S1*01	94.4	Mo_IGHV3S1*01	50.0	ANWDGDY	BBAALAB	8
H3-7-1	2ZNWB	2.71	heavy	Synthetic.construct	Mo_IGHV3S1*01	94.4	Mo_IGHV3S1*01	50.0	ANWDGDY	BBAALAB	9
H3-7-1	1GPOH	1.95	heavy	Mus.musculus	Mo_IGHV3S1*01	91.8	Mo_IGHV3S1*01	50.0	ANWHGDY	BBAALAB	8
H3-7-1	1GPOI	1.95	heavy	Mus.musculus	Mo_IGHV3S1*01	91.8	Mo_IGHV3S1*01	50.0	ANWHGDY	BBAALAB	8
H3-7-1	1NAKH	2.57	heavy	Mus.musculus	Mo_IGHV3-8*02	94.5	Mo_IGHV3-8*02	50.0	AIDDFDI	BBAALAB	19
H3-7-1	1NAKI	2.57	heavy	Mus.musculus	Mo_IGHV3-8*02	94.5	Mo_IGHV3-8*02	50.0	AIDDFDI	BBAALAB	19
H3-7-1	5AUMA	2.05	heavy	Rattus.norvegicus	Ra_IGHV10-5*01	100.0	Ra_IGHV10-5*01	100.0	TAEVATD	BBAALAB	10
H3-7-1	5AUMH	2.05	heavy	Rattus.norvegicus	Ra_IGHV10-5*01	100.0	Ra_IGHV10-5*01	100.0	TAEVATD	BBAALAB	10
H3-7-1	6E4YH	2.24	heavy	Mus.musculus	Mo_IGHV6-3*01	100.0	Mo_IGHV6-3*01	100.0	TGEIFVN	BBAALAB	17
H3-7-1	6E4ZH	2.202	heavy	Mus.musculus	Mo_IGHV6-3*01	100.0	Mo_IGHV6-3*01	100.0	TGEIFVN	BBAALAB	17
H3-7-1	6MV5H	2.1	heavy	Mus.musculus	Mo_IGHV6-3*01	100.0	Mo_IGHV6-3*01	100.0	TGEIFVN	BBAALAB	18
H3-7-1	1C08B	2.3	heavy	Mus.musculus	Mo_IGHV3S1*01	95.8	Mo_IGHV3S1*01	50.0	ANWDGDY	BBAALAB	10
H3-7-1	1DQJB	2	heavy	Mus.musculus	Mo_IGHV3S1*01	97.3	Mo_IGHV3S1*01	50.0	ASWGGDV	BBAALAB	4
H3-7-1	1DQMH	2.1	heavy	Mus.musculus	Mo_IGHV3S1*01	97.3	Mo_IGHV3S1*01	50.0	ASWGGDV	BBAALAB	11
H3-7-1	1DQQB	1.8	heavy	Mus.musculus	Mo_IGHV3S1*01	97.3	Mo_IGHV3S1*01	50.0	ASWGGDV	BBAALAB	12
H3-7-1	1DQQD	1.8	heavy	Mus.musculus	Mo_IGHV3S1*01	97.3	Mo_IGHV3S1*01	50.0	ASWGGDV	BBAALAB	12
H3-7-1	1IC4H	2.5	heavy	Mus.musculus	Mo_IGHV3-8*02	97.2	Mo_IGHV3-8*02	50.0	ANWDGDY	BBAALAB	10
H3-7-1	1IC5H	2.3	heavy	Mus.musculus	Mo_IGHV3S1*01	95.8	Mo_IGHV3S1*01	50.0	ANWAGDY	BBAALAB	7
H3-7-1	1IC7H	2.1	heavy	Mus.musculus	Mo_IGHV3-8*02	97.2	Mo_IGHV3-8*02	50.0	ANWAGDY	BBAALAB	7
H3-7-1	1J1OH	1.8	heavy	Mus.musculus	Mo_IGHV3S1*01	95.8	Mo_IGHV3S1*01	50.0	ANWDGDY	BBAALAB	8
H3-7-1	1J1PH	1.8	heavy	Mus.musculus	Mo_IGHV3S1*01	95.8	Mo_IGHV3S1*01	50.0	ANWDGDY	BBAALAB	6
H3-7-1	1J1XH	1.8	heavy	Mus.musculus	Mo_IGHV3S1*01	95.8	Mo_IGHV3S1*01	50.0	ANWDGDY	BBAALAB	6
H3-7-1	1NBYB	1.8	heavy	Mus.musculus	Mo_IGHV3S1*01	97.3	Mo_IGHV3S1*01	50.0	ASWGGDV	BBAALAB	7
H3-7-1	1NBZB	1.85	heavy	Mus.musculus	Mo_IGHV3S1*01	97.3	Mo_IGHV3S1*01	50.0	ASWGGDV	BBAALAB	7
H3-7-1	1NDGB	1.9	heavy	Mus.musculus	Mo_IGHV3S1*01	94.5	Mo_IGHV3S1*01	50.0	ANWDGTY	BBAALAB	7
H3-7-1	1NDMB	2.1	heavy	Mus.musculus	Mo_IGHV3S1*01	97.3	Mo_IGHV3S1*01	100.0	ARWEMDY	BBAALAB	8
H3-7-1	1UA6H	1.9	heavy	Mus.musculus	Mo_IGHV3S1*01	95.8	Mo_IGHV3S1*01	50.0	ANWDGDY	BBAALAB	7
H3-7-1	1UACH	1.7	heavy	Mus.musculus	Mo_IGHV3S1*01	95.8	Mo_IGHV3S1*01	50.0	ANWDGDY	BBAALAB	8
H3-7-1	1XGPB	2.1	heavy	Mus.musculus	Mo_IGHV3S1*01	97.3	Mo_IGHV3S1*01	50.0	ASWGGDV	BBAALAB	6
H3-7-1	1XGQB	2.1	heavy	Mus.musculus	Mo_IGHV3S1*01	97.3	Mo_IGHV3S1*01	50.0	ASWGGDV	BBAALAB	5
H3-7-1	1XGRB	2.1	heavy	Mus.musculus	Mo_IGHV3S1*01	97.2	Mo_IGHV3S1*01	50.0	ASWGGDV	BBAALAB	7
H3-7-1	1XGTB	2.1	heavy	Mus.musculus	Mo_IGHV3S1*01	97.3	Mo_IGHV3S1*01	50.0	ASWGGDV	BBAALAB	7
H3-7-1	1XGUB	2.1	heavy	Mus.musculus	Mo_IGHV3S1*01	97.3	Mo_IGHV3S1*01	50.0	ASWGGDV	BBAALAB	5
H3-7-1	2DQCH	1.8	heavy	Mus.musculus	Mo_IGHV3S1*01	95.8	Mo_IGHV3S1*01	50.0	ANWDGDY	BBAALAB	5
H3-7-1	2DQDH	1.8	heavy	Mus.musculus	Mo_IGHV3S1*01	95.8	Mo_IGHV3S1*01	50.0	ANWDGDY	BBAALAB	7
H3-7-1	2DQEH	1.9	heavy	Mus.musculus	Mo_IGHV3S1*01	95.8	Mo_IGHV3S1*01	50.0	ANWDGDY	BBAALAB	6
H3-7-1	2DQFB	2.5	heavy	Mus.musculus	Mo_IGHV3S1*01	95.8	Mo_IGHV3S1*01	50.0	ANWDGDY	BBAALAB	11
H3-7-1	2DQGH	2.3	heavy	Mus.musculus	Mo_IGHV3S1*01	95.8	Mo_IGHV3S1*01	50.0	ANWDGDY	BBAALAB	8
H3-7-1	2DQHH	2.3	heavy	Mus.musculus	Mo_IGHV3S1*01	95.8	Mo_IGHV3S1*01	50.0	ANWDGDY	BBAALAB	6
H3-7-1	2DQFE	2.5	heavy	Mus.musculus	Mo_IGHV3S1*01	95.8	Mo_IGHV3S1*01	50.0	ANWDGDY	BBAALAB	6
H3-7-1	2DQIH	2	heavy	Mus.musculus	Mo_IGHV3S1*01	95.8	Mo_IGHV3S1*01	50.0	ANWDGDY	BBAALAB	4
H3-7-1	2DQJH	1.8	heavy	Mus.musculus	Mo_IGHV3S1*01	95.8	Mo_IGHV3S1*01	50.0	ANWDGDY	BBAALAB	6
H3-7-1	2EIZB	1.9	heavy	Homo.sapiens	Hu_IGHV4-61*08	94.5	Hu_IGHV4-61*08	100.0	ARWDGDY	BBAALAB	10
H3-7-1	2EKSB	2	heavy	Homo.sapiens	Hu_IGHV4-61*08	95.9	Hu_IGHV4-61*08	100.0	ARWDGDY	BBAALAB	9
H3-7-1	2YSSB	2.4	heavy	Homo.sapiens	Hu_IGHV4-61*08	93.2	Hu_IGHV4-61*08	100.0	ARWDGDY	BBAALAB	9
H3-7-1	3A67H	1.8	heavy	Mus.musculus	Mo_IGHV3S1*01	95.8	Mo_IGHV3S1*01	50.0	ANWDGDY	BBAALAB	6
H3-7-1	3A6BH	1.8	heavy	Mus.musculus	Mo_IGHV3S1*01	95.8	Mo_IGHV3S1*01	50.0	ANWDGDY	BBAALAB	6
H3-7-1	3A6CH	1.8	heavy	Mus.musculus	Mo_IGHV3S1*01	95.8	Mo_IGHV3S1*01	50.0	ANWDGDY	BBAALAB	5
H3-7-1	3D9AH	1.2	heavy	Mus.musculus	Mo_IGHV3S1*01	95.8	Mo_IGHV3S1*01	50.0	ANWDGDY	BBAALAB	7
H3-7-1	4CKDJ	EM	heavy	Mus.musculus	Mo_IGHV3S1*01	95.8	Mo_IGHV3S1*01	50.0	ANWDGDY	BBAALAB	6
H3-7-1	4CKDI	EM	heavy	Mus.musculus	Mo_IGHV3S1*01	95.8	Mo_IGHV3S1*01	50.0	ANWDGDY	BBAALAB	6
H3-7-1	4CKDH	EM	heavy	Mus.musculus	Mo_IGHV3S1*01	95.8	Mo_IGHV3S1*01	50.0	ANWDGDY	BBAALAB	6
H3-7-1	4CKDK	EM	heavy	Mus.musculus	Mo_IGHV3S1*01	95.8	Mo_IGHV3S1*01	50.0	ANWDGDY	BBAALAB	6
H3-7-1	5AYUH	1.8	heavy	Mus.musculus	Mo_IGHV3S1*01	95.8	Mo_IGHV3S1*01	50.0	ANWDGDY	BBAALAB	11
H3-7-1	5VJOA	2.43	heavy	Mus.musculus	Mo_IGHV3S1*01	95.8	Mo_IGHV3S1*01	50.0	ANWDGDY	BBAALAB	8
H3-7-1	5VJQE	1.9	heavy	Mus.musculus	Mo_IGHV3S1*01	95.8	Mo_IGHV3S1*01	50.0	ANWDGDY	BBAALAB	5
H3-7-1	5VJOC	2.43	heavy	Mus.musculus	Mo_IGHV3S1*01	95.8	Mo_IGHV3S1*01	50.0	ANWDGDY	BBAALAB	8
H3-7-1	5VJQC	1.9	heavy	Mus.musculus	Mo_IGHV3S1*01	95.8	Mo_IGHV3S1*01	50.0	ANWDGDY	BBAALAB	5
H3-7-1	5VJQA	1.9	heavy	Mus.musculus	Mo_IGHV3S1*01	95.8	Mo_IGHV3S1*01	50.0	ANWDGDY	BBAALAB	6
H3-7-1	5VJQG	1.9	heavy	Mus.musculus	Mo_IGHV3S1*01	95.8	Mo_IGHV3S1*01	50.0	ANWDGDY	BBAALAB	5
H3-7-1	6OKMH	2.1	heavy	Homo.sapiens	Hu_IGHV1-46*01	87.7	Hu_IGHV1-46*01	100.0	ARDRLDY	BBAALAB	9
H3-7-1	6OGXH	2.77	heavy	Homo.sapiens	Hu_IGHV1-46*01	87.7	Hu_IGHV1-46*01	100.0	ARDRLDY	BBAALAB	10
H3-7-1	6P4AH	2.2	heavy	Mus.musculus	Mo_IGHV3S1*01	95.8	Mo_IGHV3S1*01	50.0	ANWDGDY	BBAALAB	9
H3-7-1	6P4BH	1.9	heavy	Mus.musculus	Mo_IGHV3S1*01	94.4	Mo_IGHV3S1*01	50.0	ANWDGDY	BBAALAB	11
H3-7-1	6P4CH	1.85	heavy	Mus.musculus	Mo_IGHV3S1*01	94.4	Mo_IGHV3S1*01	50.0	ANWDGDY	BBAALAB	11
H3-7-1	6P4BB	1.9	heavy	Mus.musculus	Mo_IGHV3S1*01	94.4	Mo_IGHV3S1*01	50.0	ANWDGDY	BBAALAB	8
H3-7-1	1N7ML	1.8	heavy	Mus.musculus.Homo.sapiens	Mo_IGHV1-72*03	95.1	Mo_IGHV1-72*03	0.0	TRRDSDY	BBAALAB	11
H3-7-1	1NGWH	2.6	heavy	Mus.musculus.Homo.sapiens	Mo_IGHV1S36*01	94.4	Mo_IGHV1S36*01	100.0	TRRDMDY	BBAALAB	18
H3-7-1	1NGWB	2.6	heavy	Mus.musculus.Homo.sapiens	Mo_IGHV1S36*01	94.4	Mo_IGHV1S36*01	100.0	TRRDMDY	BBAALAB	18
H3-7-1	1NGYB	2.2	heavy	Mus.musculus.Homo.sapiens	Mo_IGHV1S36*01	94.4	Mo_IGHV1S36*01	100.0	TRRDMDY	BBAALAB	15
H3-7-1	3FCTB	2.4	heavy	Homo.sapiens	Mo_IGHV1S36*01	94.4	Mo_IGHV1S36*01	100.0	TRRDMDY	BBAALAB	15
H3-7-1	3FCTD	2.4	heavy	Homo.sapiens	Mo_IGHV1S36*01	94.4	Mo_IGHV1S36*01	100.0	TRRDMDY	BBAALAB	12

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022