PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDR Structures for H3-5-2

Summary info for H3-5-2
Loop	# of Structures	% of Loop Length	Median PDB	Consensus Sequence	# of Unique Seq	% of Unique Seq	Gene	Loop Conformation	Median Angle	Consensus Sequence Logo
H3-5-2	36	38.71	21H_4WHTQ	TrRDY	6	23.08	heavy	BAEAB	8

Structures in cluster H3-5-2
Cluster	PDB	Resolution	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	Sequence	Ramachandran	Distance(°)
H3-5-2	4WHTQ	2.22	heavy	Rattus.norvegicus	Ra_IGHV5-20*01	95.9	Ra_IGHV5-20*01	50.0	TRMDY	BAEAB	5
H3-5-2	4WHYK	2.62	heavy	Rattus.norvegicus	Ra_IGHV5-20*01	95.9	Ra_IGHV5-20*01	50.0	TRMDY	BAEAB	11
H3-5-2	4WHTM	2.22	heavy	Rattus.norvegicus	Ra_IGHV5-20*01	95.9	Ra_IGHV5-20*01	50.0	TRMDY	BAEAB	6
H3-5-2	4WHYI	2.62	heavy	Rattus.norvegicus	Ra_IGHV5-20*01	95.9	Ra_IGHV5-20*01	50.0	TRMDY	BAEAB	10
H3-5-2	4WHTS	2.22	heavy	Rattus.norvegicus	Ra_IGHV5-20*01	95.9	Ra_IGHV5-20*01	50.0	TRMDY	BAEAB	5
H3-5-2	4WHYG	2.62	heavy	Rattus.norvegicus	Ra_IGHV5-20*01	95.9	Ra_IGHV5-20*01	50.0	TRMDY	BAEAB	9
H3-5-2	4XXDB	2.41	heavy	Homo.sapiens	Hu_IGHV3-74*03	93.2	Hu_IGHV3-74*03	50.0	ASGDY	BAEAB	9
H3-5-2	4WHYM	2.62	heavy	Rattus.norvegicus	Ra_IGHV5-20*01	95.9	Ra_IGHV5-20*01	50.0	TRMDY	BAEAB	12
H3-5-2	4WHTC	2.22	heavy	Rattus.norvegicus	Ra_IGHV5-20*01	95.9	Ra_IGHV5-20*01	50.0	TRMDY	BAEAB	5
H3-5-2	4XXDE	2.41	heavy	Homo.sapiens	Hu_IGHV3-74*03	93.2	Hu_IGHV3-74*03	50.0	ASGDY	BAEAB	12
H3-5-2	4WHTO	2.22	heavy	Rattus.norvegicus	Ra_IGHV5-20*01	95.9	Ra_IGHV5-20*01	50.0	TRMDY	BAEAB	5
H3-5-2	4WHTI	2.22	heavy	Rattus.norvegicus	Ra_IGHV5-20*01	95.9	Ra_IGHV5-20*01	50.0	TRMDY	BAEAB	5
H3-5-2	4WHTE	2.22	heavy	Rattus.norvegicus	Ra_IGHV5-20*01	95.9	Ra_IGHV5-20*01	50.0	TRMDY	BAEAB	5
H3-5-2	4WHTA	2.22	heavy	Rattus.norvegicus	Ra_IGHV5-20*01	95.9	Ra_IGHV5-20*01	50.0	TRMDY	BAEAB	6
H3-5-2	4WHTU	2.22	heavy	Rattus.norvegicus	Ra_IGHV5-20*01	95.9	Ra_IGHV5-20*01	50.0	TRMDY	BAEAB	6
H3-5-2	4WHTG	2.22	heavy	Rattus.norvegicus	Ra_IGHV5-20*01	95.9	Ra_IGHV5-20*01	50.0	TRMDY	BAEAB	5
H3-5-2	4WHTK	2.22	heavy	Rattus.norvegicus	Ra_IGHV5-20*01	95.9	Ra_IGHV5-20*01	50.0	TRMDY	BAEAB	5
H3-5-2	4WHTX	2.22	heavy	Rattus.norvegicus	Ra_IGHV5-20*01	95.9	Ra_IGHV5-20*01	50.0	TRMDY	BAEAB	6
H3-5-2	5VZXE	2.501	heavy	Homo.sapiens	Hu_IGHV3-7*01	97.3	Hu_IGHV3-7*01	50.0	ASGDY	BALAB	7
H3-5-2	5VZYH	2.32	heavy	Homo.sapiens	Hu_IGHV3-7*01	97.3	Hu_IGHV3-7*01	50.0	ASGDY	BAEAB	10
H3-5-2	5VZXH	2.501	heavy	Homo.sapiens	Hu_IGHV3-7*01	97.3	Hu_IGHV3-7*01	50.0	ASGDY	BAEAB	9
H3-5-2	6OBDB	2.2	heavy	Mus.musculus	Hu_IGHV3-72*01	98.6	Hu_IGHV3-72*01	0.0	TPIDY	BALAB	12
H3-5-2	6OBDH	2.2	heavy	Mus.musculus	Hu_IGHV3-72*01	98.6	Hu_IGHV3-72*01	0.0	TPIDY	BALAB	13
H3-5-2	6PDUH	1.953	heavy	Homo.sapiens	Hu_IGHV3-64*04	86.3	Hu_IGHV3-64*04	0.0	TDFDF	BALAB	8
H3-5-2	1BOGB	2.6	heavy	Mus.musculus	Mo_IGHV1-23*01	94.4	Mo_IGHV1-23*01	100.0	TRKDY	BALAB	19
H3-5-2	1CFNB	2.65	heavy	Mus.musculus	Mo_IGHV1-23*01	94.4	Mo_IGHV1-23*01	100.0	TRKDY	BALAB	14
H3-5-2	1CFQB	2.8	heavy	Mus.musculus	Mo_IGHV1-23*01	94.4	Mo_IGHV1-23*01	100.0	TRKDY	BALAB	11
H3-5-2	1CFSB	2.75	heavy	Mus.musculus	Mo_IGHV1-23*01	94.4	Mo_IGHV1-23*01	100.0	TRKDY	BALAB	8
H3-5-2	1CFTB	2.8	heavy	Mus.musculus	Mo_IGHV1-23*01	94.4	Mo_IGHV1-23*01	100.0	TRKDY	BALAB	16
H3-5-2	1HH6B	2.6	heavy	Mus.musculus	Mo_IGHV1-23*01	94.4	Mo_IGHV1-23*01	100.0	TRKDY	BALAB	16
H3-5-2	1HH9B	2.7	heavy	Mus.musculus	Mo_IGHV1-23*01	94.4	Mo_IGHV1-23*01	100.0	TRKDY	BALAB	14
H3-5-2	1HI6B	2.55	heavy	Mus.musculus	Mo_IGHV1-23*01	94.4	Mo_IGHV1-23*01	100.0	TRKDY	BALAB	16
H3-5-2	7Y0GE	2.08	heavy	Homo.sapiens	Hu_IGHV3-73*01	98.6	Hu_IGHV3-73*01	0.0	SNRYY	BALAB	14
H3-5-2	7Y0GB	2.08	heavy	Homo.sapiens	Hu_IGHV3-73*01	98.6	Hu_IGHV3-73*01	0.0	SNRYY	BALAB	11
H3-5-2	7Y0GH	2.08	heavy	Homo.sapiens	Hu_IGHV3-73*01	98.6	Hu_IGHV3-73*01	0.0	SNRYY	BALAB	11
H3-5-2	7Y0GK	2.08	heavy	Homo.sapiens	Hu_IGHV3-73*01	98.6	Hu_IGHV3-73*01	0.0	SNRYY	BALAB	15

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022