PyIgClassify: An antibody CDRs clusters web site

Clusters of Antibody CDR Loop Conformations

CDR Structures for L2-12-2

Summary info for L2-12-2
Loop	# of Structures	% of Loop Length	Median PDB	Consensus Sequence	# of Unique Seq	% of Unique Seq	Species	Gene	Loop Conformation	Median Angle	Consensus Sequence Logo
L2-12-2	19	73.08	2OTUC	elkkDGSHntGD	7	53.85	Hu Mo	lambda	BBPAALPBBPPP	19

Structures in cluster L2-12-2
Cluster	PDB	Resolution	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	Sequence	Ramachandran	Distance(°)
L2-12-2	2GSGA	2.1	lambda	Mus.musculus	Mo_IGLV3*01	100	Mo_IGLV3*01	100	ELKKDGSHSTGD	BBPAALPBBPPP	9
L2-12-2	2GSGC	2.1	lambda	Mus.musculus	Mo_IGLV3*01	100	Mo_IGLV3*01	100	ELKKDGSHSTGD	BBPAALPBBPPP	10
L2-12-2	2OTUA	1.68	lambda	Mus.musculus	Mo_IGLV3*01	100	Mo_IGLV3*01	100	ELKKDGSHSTGD	BBPAALPBBPPP	9
L2-12-2	2OTUC	1.68	lambda	Mus.musculus	Mo_IGLV3*01	100	Mo_IGLV3*01	100	ELKKDGSHSTGD	BBPAALPBBPPP	0
L2-12-2	2OTUE	1.68	lambda	Mus.musculus	Mo_IGLV3*01	100	Mo_IGLV3*01	100	ELKKDGSHSTGD	BBPAALPBBPPP	6
L2-12-2	2OTUG	1.68	lambda	Mus.musculus	Mo_IGLV3*01	100	Mo_IGLV3*01	100	ELKKDGSHSTGD	BBPAALPBBPPP	7
L2-12-2	2OTWA	2.35	lambda	Mus.musculus	Mo_IGLV3*01	100	Mo_IGLV3*01	100	ELKKDGSHSTGD	BBPAALPBBPPP	9
L2-12-2	2OTWC	2.35	lambda	Mus.musculus	Mo_IGLV3*01	100	Mo_IGLV3*01	100	ELKKDGSHSTGD	BBPAALPBBPPP	10
L2-12-2	2QHRL	2	lambda	Mus.musculus	Mo_IGLV3*01	98.5	Mo_IGLV3*01	100	ELKKDGSHSTGD	PBPAALPBBPPP	7
L2-12-2	3FFDB	2	lambda	Mus.musculus	Mo_IGLV3*01	98.5	Mo_IGLV3*01	83.3	DLKQDGSHSTGD	BBPAALPBBPPP	9
L2-12-2	3S96D	1.9	lambda	Mus.musculus	Mo_IGLV3*01	100	Mo_IGLV3*01	100	ELKKDGSHSTGD	BBPAALPBBPPP	12
L2-12-2	4DCQA	1.94	lambda	Mus.musculus	Mo_IGLV3*01	98.5	Mo_IGLV3*01	100	ELKKDGSHSTGD	BBPAALPBBPPP	11
L2-12-2	4ISVA	1.497	lambda	Mus.musculus	Mo_IGLV3*01	97.1	Mo_IGLV3*01	100	ELKKDGSHSTGD	BBPAALPBBBPP	10
L2-12-2	4JJ5A	2.445	lambda	Mus.musculus	Mo_IGLV3*01	97.1	Mo_IGLV3*01	100	ELKKDGSHSTGD	BBPAALPBBPPP	7
L2-12-2	5EORL	2.27	lambda	Mus.musculus	Mo_IGLV3*01	100	Mo_IGLV3*01	75	ELRRDGSHNTGD	PBPAALPBBPPP	7
L2-12-2	5IFJB	2.35	lambda	Homo.sapiens	Hu_IGLV4-69*01	97.1	Hu_IGLV4-69*01	91.7	KVNSDGSHSKGD	BBBAAGGBBPPP	34
L2-12-2	5IFJE	2.35	lambda	Homo.sapiens	Hu_IGLV4-69*01	97.1	Hu_IGLV4-69*01	91.7	KVNSDGSHSKGD	BBBAAGGBBPPP	35
L2-12-2	5IFJH	2.35	lambda	Homo.sapiens	Hu_IGLV4-69*01	97.1	Hu_IGLV4-69*01	91.7	KVNSDGSHSKGD	BBBAAGGBBPPP	35
L2-12-2	5IFJK	2.35	lambda	Homo.sapiens	Hu_IGLV4-69*01	97.1	Hu_IGLV4-69*01	91.7	KVNSDGSHSKGD	BBBAAGGBBPPP	34
L2-12-2	5IG7B	1.97	lambda	Homo.sapiens	Hu_IGLV4-69*01	97.1	Hu_IGLV4-69*01	91.7	KVNSDGSHSKGD	BBBAAGGBBPPP	35
L2-12-2	5IG7E	1.97	lambda	Homo.sapiens	Hu_IGLV4-69*01	97.1	Hu_IGLV4-69*01	91.7	KVNSDGSHSKGD	BBBAAGGBBPPP	34
L2-12-2	5IG7H	1.97	lambda	Homo.sapiens	Hu_IGLV4-69*01	97.1	Hu_IGLV4-69*01	91.7	KVNSDGSHSKGD	BBBAAGGBBPPP	34
L2-12-2	5IG7K	1.97	lambda	Homo.sapiens	Hu_IGLV4-69*01	97.1	Hu_IGLV4-69*01	91.7	KVNSDGSHSKGD	BBBAAGGBBPPP	35
L2-12-2	5IHZD	1.64	lambda	Homo.sapiens	Hu_IGLV4-69*01	97.1	Hu_IGLV4-69*01	91.7	KVNSDGSHSKGD	BBBAALPBBPPP	15
L2-12-2	5IHZF	1.64	lambda	Homo.sapiens	Hu_IGLV4-69*01	97.1	Hu_IGLV4-69*01	91.7	KVNSDGSHSKGD	BBPADLPBBPPP	14
L2-12-2	5IHZL	1.64	lambda	Homo.sapiens	Hu_IGLV4-69*01	97.1	Hu_IGLV4-69*01	91.7	KVNSDGSHSKGD	BBBAALPBBBPP	15
L2-12-2	5KG9B	2.3	lambda	Mus.musculus.Homo.sapiens	Mo_IGLV3*01	98.5	Mo_IGLV3*01	83.3	ELRKDGSHNTGD	BBPAALPBBPPP	10
L2-12-2	5KG9L	2.3	lambda	Mus.musculus.Homo.sapiens	Mo_IGLV3*01	98.5	Mo_IGLV3*01	83.3	ELRKDGSHNTGD	BBPAALPBBPPP	14
L2-12-2	6A4KL	3.15	lambda	Homo.sapiens	Hu_IGLV4-69*01	84	Hu_IGLV4-69*01	50	NLSSGGRHTRGD	BBPADLPBBPPP	18
L2-12-2	6A4KM	3.15	lambda	Homo.sapiens	Hu_IGLV4-69*01	84	Hu_IGLV4-69*01	50	NLSSGGRHTRGD	BBPABLPBBPPP	19
L2-12-2	6A4KN	3.15	lambda	Homo.sapiens	Hu_IGLV4-69*01	84	Hu_IGLV4-69*01	50	NLSSGGRHTRGD	BBPAALPBBPPP	14
L2-12-2	6A4KO	3.15	lambda	Homo.sapiens	Hu_IGLV4-69*01	84	Hu_IGLV4-69*01	50	NLSSGGRHTRGD	BBPAALPBBPPP	15
L2-12-2	6BE2L	1.7	lambda	Homo.sapiens	Hu_IGLV4-69*01	97.1	Hu_IGLV4-69*01	66.7	KVNRDGSHIRGD	BBPAALPBBPPP	9
L2-12-2	6BE3L	1.6	lambda	Homo.sapiens	Hu_IGLV4-69*01	97.1	Hu_IGLV4-69*01	66.7	KVNRDGSHIRGD	BBPAALPBBPPP	8
L2-12-2	6BE4L	1.9	lambda	Homo.sapiens	Hu_IGLV4-69*01	97.1	Hu_IGLV4-69*01	66.7	KVNRDGSHIRGD	BBPAALPBBPPP	8
L2-12-2	6F7TA	2.6	lambda	Mus.musculus	Mo_IGLV3*01	94.5	Mo_IGLV3*01	100	ELKKDGSHSTGD	BBPAALPBBPPP	10
L2-12-2	6F7TL	2.6	lambda	Mus.musculus	Mo_IGLV3*01	94.5	Mo_IGLV3*01	100	ELKKDGSHSTGD	BBPAALPBBPPP	10

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on November 1, 2019