PyIgClassify: An antibody CDRs clusters web site

FCCC

Clusters of Antibody CDR Loop Conformations

Dunbrack Lab

CDR Structures for H2-10-9

Summary info for H2-10-9
Loop	# of Structures	% of Loop Length	Median PDB	Consensus Sequence	# of Unique Seq	% of Unique Seq	Species	Gene	Loop Conformation	Median Angle	Consensus Sequence Logo
H2-10-9	6	0.22	1UWGY	gIdpigggak	6	0.44	Ca Hu Mo	heavy	BBPDALPBPB	28

Structures in cluster H2-10-9
Cluster	PDB	Resolution	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	Sequence	Ramachandran	Distance(°)
H2-10-9	1A6VJ	1.8	heavy	Mus.musculus	Mo_IGHV1-72*01	100	Mo_IGHV1-72*01	100	RIDPNSGGTK	BBBAPLGBBB	33
H2-10-9	1RZIL	2.9	heavy	Homo.sapiens	Hu_IGHV1-69*01	94.5	Hu_IGHV1-69*01	80	GIIPVFGSAN	BBBAABPGBP	31
H2-10-9	1RZIP	2.9	heavy	Homo.sapiens	Hu_IGHV1-69*01	94.5	Hu_IGHV1-69*01	80	GIIPVFGSAN	BBBAABPBPB	33
H2-10-9	1UWGH	2.79	heavy	Homo.sapiens	Mo_IGHV1S135*01	90.4	Mo_IGHV1S135*01	60	GIDPHNGGPV	BBPADBPGPB	7
H2-10-9	1UWGY	2.79	heavy	Homo.sapiens	Mo_IGHV1S135*01	90.4	Mo_IGHV1S135*01	60	GIDPHNGGPV	BBBADBPGPB	0
H2-10-9	2V7NB	1.92	heavy	Synthetic.construct	Hu_IGHV3-33*01	95.9	Hu_IGHV3-33*01	70	SIWYSGSNTY	BBPDALPBPB	31
H2-10-9	3NPSB	1.5	heavy	Homo.sapiens	Hu_IGHV1-69*01	97.3	Hu_IGHV1-69*01	100	GIIPIFGTAN	BBPAADPBPB	39
H2-10-9	5KWL7	EM	heavy	Camelus.dromedarius	Ca_IGHV1S47*01_VHH	88.9	Ca_IGHV1S47*01_VHH	50	AIDSSGVGTT	BBPAPLPBPB	29

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on November 1, 2019

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