PyIgClassify: An antibody CDRs clusters web site

FCCC

Clusters of Antibody CDR Loop Conformations

Dunbrack Lab

CDR Structures for H1-12-1

Summary info for H1-12-1
Loop	# of Structures	% of Loop Length	Median PDB	Consensus Sequence	# of Unique Seq	% of Unique Seq	Species	Gene	Loop Conformation	Median Angle	Consensus Sequence Logo
H1-12-1	3	33.33	1GHFH	KagfnfkDvgMn	2	33.33	CDRLenMismatch	heavy	PBABPAAABBBB	31

Structures in cluster H1-12-1
Cluster	PDB	Resolution	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	Sequence	Ramachandran	Distance(°)
H1-12-1	1GHFH	2.7	heavy	Mus.musculus	Mo_IGHV9-2*02	91.7	CDRLenMismatch	-1	KLWYTFTDYGMN	BBBBPAAABPBB	0
H1-12-1	5AAMA	2.49	heavy	Mus.musculus	Hu_IGHV1-46*01	87.7	CDRLenMismatch	-1	KAGFNIKDVYMS	BPABPAAABBBB	29
H1-12-1	5AAMB	2.49	heavy	Mus.musculus	Hu_IGHV1-46*01	87.7	CDRLenMismatch	-1	KAGFNIKDVYMS	PBABPAAABBBB	29
H1-12-1	5AAWA	3.27	heavy	Mus.musculus	Hu_IGHV1-46*01	87.7	CDRLenMismatch	-1	KAGFNIKDVYMS	PPABPAADBBPB	35
H1-12-1	5AAWB	3.27	heavy	Mus.musculus	Hu_IGHV1-46*01	87.7	CDRLenMismatch	-1	KAGFNIKDVYMS	PBABPAADBBPB	35
H1-12-1	5AAWD	3.27	heavy	Mus.musculus	Hu_IGHV1-46*01	87.7	CDRLenMismatch	-1	KAGFNIKDVYMS	PBABPAADBBPB	35
H1-12-1	5AAWF	3.27	heavy	Mus.musculus	Hu_IGHV1-46*01	87.7	CDRLenMismatch	-1	KAGFNIKDVYMS	PBABPAAABBPB	30
H1-12-1	5AAWH	3.27	heavy	Mus.musculus	Hu_IGHV1-46*01	87.7	CDRLenMismatch	-1	KAGFNIKDVYMS	PBABPAADBBPB	35
H1-12-1	5AAWK	3.27	heavy	Mus.musculus	Hu_IGHV1-46*01	87.7	CDRLenMismatch	-1	KAGFNIKDVYMS	PBABPAADBBPB	35

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on November 1, 2019

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