Protein Common Interface Database

Clusters with M>=20,SeqId<90 and single Pfam Architecture

Pfam Architecture	Cluster#	#CFs/Cluster	#Entries/Cluster	#CFs/Group	#Entries/Group	Minimum Seq Identity	Surface Area	In PDBBA(%)	In PISABA(%)	CFs Cluster/Group(%)
(ABM)	1	27	39	39	53	3	1359	90	100	69
(Acyl-CoA_dh_N)_(Acyl-CoA_dh_M)_(Acyl-CoA_dh_1)	1	55	76	56	77	0	1844	92	96	98
(Acyl-CoA_dh_N)_(Acyl-CoA_dh_M)_(Acyl-CoA_dh_1)	2	54	75	56	77	0	2036	91	96	96
(Acyl-CoA_dh_N)_(Acyl-CoA_dh_M)_(Acyl-CoA_dh_1)	3	22	30	56	77	15	252	87	97	39
(AIRS)_(AIRS_C)	1	25	39	26	40	7	2391	87	100	96
(Adeno_knob)	1	20	37	21	39	16	1026	92	92	95
(AlaDh_PNT_N)_(AlaDh_PNT_C)	1	21	38	24	42	0	1765	97	97	88
(OTCace_N)_(OTCace)	1	53	137	54	140	0	1120	96	100	98
(Ribonuc_red_sm)	1	29	83	29	85	0	2447	93	94	100
(PDGF)	1	40	43	42	45	0	1296	95	95	95
(Chal_sti_synt_N)_(Chal_sti_synt_C)	1	23	52	23	52	19	2679	98	100	100
(CutA1)	1	22	30	22	30	22	1107	90	100	100
(tRNA-synt_2b)_(HGTP_anticodon)	1	22	39	22	39	0	2625	100	97	100
(MIP)	1	22	42	31	51	18	1704	100	98	71
(Enolase_N)_(MR_MLE_C)	1	28	46	30	50	17	1304	67	100	93
(Enolase_N)_(MR_MLE_C)	2	28	46	30	50	17	2323	93	100	93
(Enolase_N)_(MR_MLE_C)	3	27	44	30	50	17	863	61	100	90
(OMPdecase)	1	55	225	56	229	0	1726	95	100	98
(OsmC)	1	21	25	23	27	6	3113	100	100	91
(Peripla_BP_3)_(Peripla_BP_3)	1	21	27	23	29	12	1592	93	93	91
(PGI)	1	21	51	21	51	14	6138	98	100	100
(PK)_(PK_C)	1	38	73	39	75	0	1163	97	90	97
(PK)_(PK_C)	2	37	72	39	75	0	2513	97	99	95
(Sod_Fe_N)_(Sod_Fe_C)	1	58	128	60	132	19	884	95	96	97
(Sulfotransfer_1)	1	24	50	37	70	21	371	12	0	65
(TetR_N)_(TetR_C)	1	26	58	27	59	0	2540	98	97	96
(TetR_N)_(TetR_C_6)	1	31	37	31	37	7	1707	97	92	100
(14-3-3)	1	49	113	50	114	0	1003	88	91	98
(MHC_I)_(C1-set)	1	52	94	319	744	0	662	3	7	16
(MHC_I)_(C1-set)	2	32	96	319	744	0	503	0	0	10
(MHC_I)_(C1-set)	3	27	88	319	744	0	499	0	0	8
(MHC_I)_(C1-set)	4	22	128	319	744	0	290	1	0	7
(MHC_I)_(C1-set)	5	20	26	319	744	69	295	0	0	6
(Histone)	1	30	146	31	162	0	601	96	94	97
(Thioredoxin)	1	20	41	111	161	20	566	49	80	18
(Peptidase_M16)_(Peptidase_M16_C)	1	21	58	28	65	0	1787	95	91	75
(2-Hacid_dh_C)	1	51	71	55	82	0	2842	90	99	93
(4HBT)	1	81	141	82	144	3	1312	96	98	99
(4HBT)	2	33	67	82	144	10	538	78	81	40
(4HBT)	3	25	43	82	144	10	284	65	81	30
(V-set)_(C1-set)	1	1383	1987	1553	2288	0	1718	100	94	89
(V-set)_(C1-set)	2	188	253	1553	2288	0	376	1	4	12
(V-set)_(C1-set)	3	75	153	1553	2288	0	413	0	1	5
(V-set)_(C1-set)	4	63	114	1553	2288	0	281	0	4	4
(V-set)_(C1-set)	5	63	74	1553	2288	0	216	3	1	4
(V-set)_(C1-set)	6	54	76	1553	2288	0	590	0	3	3
(V-set)_(C1-set)	7	38	52	1553	2288	0	385	0	6	2
(V-set)_(C1-set)	8	37	39	1553	2288	11	748	5	13	2
(V-set)_(C1-set)	9	31	41	1553	2288	0	490	0	22	2
(V-set)_(C1-set)	10	30	37	1553	2288	0	347	0	8	2
(V-set)_(C1-set)	11	29	41	1553	2288	0	371	5	20	2
(V-set)_(C1-set)	12	28	31	1553	2288	0	312	0	3	2
(V-set)_(C1-set)	13	26	34	1553	2288	0	277	15	29	2
(V-set)_(C1-set)	14	23	29	1553	2288	18	733	0	3	1
(V-set)_(C1-set)	15	21	27	1553	2288	20	886	19	48	1
(V-set)_(C1-set)	16	21	24	1553	2288	0	334	0	0	1
(IL8)	1	31	55	63	111	10	759	82	71	49
(IL8)	2	25	50	63	111	0	818	84	50	40
(V-set)	1	198	295	529	699	0	813	95	86	37
(V-set)	2	55	75	529	699	0	509	13	15	10
(V-set)	3	26	30	529	699	1	417	7	17	5
(Phage_lysozyme)	1	20	503	67	586	82	744	0	4	30
(DPPIV_N)_(Peptidase_S9)	1	26	120	39	150	0	2164	95	98	67
(Serpin)	1	28	37	131	183	0	2242	95	97	21
(Trypsin)	1	23	55	457	1963	10	2816	98	98	5
(Collagen)	1	24	43	31	50	0	918	100	95	77
(P-II)	1	47	71	47	73	0	1114	100	97	100
(Proteasome)	1	55	327	56	370	0	690	100	82	98
(Proteasome)	2	45	316	56	370	0	963	99	81	80
(Proteasome)	3	45	314	56	370	0	704	99	82	80
(Proteasome)	4	22	196	56	370	0	633	100	70	39
(Proteasome_A_N)_(Proteasome)	1	33	283	38	328	0	1346	100	82	87
(PCNA_N)_(PCNA_C)	1	52	68	60	77	0	655	84	66	87
(Globin)	1	83	366	174	1079	0	852	99	96	48
(Globin)	2	72	348	174	1079	0	584	95	77	41
(Globin)	3	56	234	174	1079	0	284	95	78	32
(Carboxyl_trans)	1	25	48	25	48	0	4726	98	85	100
(Iso_dh)	1	65	156	65	156	0	2723	99	99	100
(Orn_Arg_deC_N)_(Orn_DAP_Arg_deC)	1	25	33	29	39	10	2798	94	100	86
(Acetyltransf_3)	1	26	40	42	59	11	1004	78	70	62
(ACP_syn_III)_(ACP_syn_III_C)	1	40	75	40	75	12	2720	95	99	100
(Actin)	1	29	29	124	191	51	593	100	10	23
(Lectin_C)	1	29	36	121	183	16	1831	92	100	24
(TGF_beta)	1	56	72	56	72	0	1289	94	86	100
(Tubulin)_(Tubulin_C)	1	64	119	76	137	0	1380	99	63	84
(ADH_N)_(ADH_zinc_N)	1	80	179	84	183	0	1560	93	96	95
(ADH_N)_(ADH_zinc_N)	2	38	58	84	183	11	514	78	78	45
(ADH_N)_(ADH_zinc_N)	3	34	48	84	183	14	620	83	83	40
(adh_short_C2)	1	342	688	354	752	0	1214	95	98	97
(adh_short_C2)	2	336	693	354	752	0	1484	93	96	95
(ketoacyl-synt)_(Ketoacyl-synt_C)_(KAsynt_C_assoc)	1	20	46	20	46	0	2688	96	96	100
(adh_short)	1	81	153	89	171	0	2203	94	97	91
(adh_short)	2	21	23	89	171	12	1222	91	96	24
(Pkinase)	1	25	97	558	2723	0	516	1	0	4
(Redoxin)	1	31	43	41	54	0	755	70	91	76
(AhpC-TSA)_(1-cysPrx_C)	1	43	84	43	87	0	1769	99	98	100
(AhpC-TSA)_(1-cysPrx_C)	2	32	70	43	87	0	687	96	83	74
(tRNA_anti-codon)_(tRNA-synt_2)	1	25	40	25	40	0	4172	100	100	100
(Ala_racemase_N)_(Ala_racemase_C)	1	24	48	30	57	18	2871	100	96	80
(Aldedh)	1	104	265	110	278	0	2899	100	100	95
(Aldedh)	2	65	180	110	278	0	1110	89	92	59
(Aldedh)	3	64	179	110	278	0	947	90	92	58
(Lectin_legB)	1	72	230	94	287	0	945	95	78	77
(Lectin_legB)	2	26	43	94	287	49	878	98	77	28
(Lectin_legB)	3	21	59	94	287	59	974	90	86	22
(Lectin_legB)	4	20	68	94	287	32	862	88	65	21
(Amidohydro_1)	1	22	39	73	133	10	2563	64	100	30
(Aminotran_1_2)	1	131	298	153	347	0	3079	98	99	86
(Aminotran_3)	1	72	181	72	197	12	4669	96	99	100
(Aminotran_4)	1	38	82	42	96	0	2345	98	100	90
(Aminotran_5)	1	64	109	68	115	0	2849	97	100	94
(Hormone_recep)	1	118	311	264	871	0	1119	63	52	45
(C1-set)_(C1-set)	1	61	107	76	143	0	1118	87	85	80
(Peptidase_C14)	1	69	200	75	215	0	922	78	96	92
(Peptidase_C14)	2	25	104	75	215	0	2233	100	100	33
(GFP)	1	75	152	198	537	0	1277	68	84	38
(GFP)	2	73	152	198	537	0	865	57	61	37
(GFP)	3	44	71	198	537	0	787	23	31	22
(S_100)_(EF-hand_1)	1	61	152	67	160	0	1465	100	62	91
(EF-hand_7)_(EF-hand_7)	1	24	35	118	174	0	502	3	11	20
(LSM)	1	38	47	40	49	0	825	100	77	95
(ELFV_dehydrog_N)_(ELFV_dehydrog)	1	31	52	31	52	0	1323	94	81	100
(ELFV_dehydrog_N)_(ELFV_dehydrog)	2	28	45	31	52	0	1349	100	80	90
(ELFV_dehydrog_N)_(ELFV_dehydrog)	3	25	42	31	52	15	419	100	79	81
(Asparaginase)	1	25	45	27	49	0	2150	100	100	93
(ATP-synt_C)	1	29	52	30	52	0	1337	100	73	97
(Avidin)	1	48	230	52	247	0	1633	97	98	92
(Avidin)	2	40	218	52	247	0	509	95	94	77
(Pkinase_Tyr)	1	27	86	398	1204	0	1232	37	42	7
(Bac_luciferase)	1	21	25	25	29	8	2220	88	100	84
(TNF)	1	55	72	63	87	0	1010	89	93	87
(Pyr_redox_2)_(Pyr_redox_dim)	1	74	154	77	158	0	3401	95	100	96
(BMC)	1	27	43	28	45	9	1039	100	98	96
(BTB)	1	30	38	30	38	10	1719	87	95	100
(GP41)	1	31	58	63	121	0	1110	98	88	49
(C1q)	1	21	28	22	30	7	968	96	93	95
(GP120)	1	21	60	114	188	0	454	0	2	18
(Enolase_N)_(Enolase_C)	1	33	69	33	70	5	1822	96	99	100
(Fe-ADH)	1	23	28	23	29	11	1474	82	89	100
(Hemagglutinin)	1	91	303	127	354	0	636	95	94	72
(Hemagglutinin)	2	82	278	127	354	0	2725	100	95	65
(Neur)	1	34	177	37	184	0	1648	98	88	92
(PNP_UDP_1)	1	44	166	128	386	7	1842	99	99	34
(PNP_UDP_1)	2	37	65	128	386	10	1631	97	98	29
(PNP_UDP_1)	3	34	118	128	386	15	1140	92	97	27
(PNP_UDP_1)	4	32	148	128	386	20	1314	97	99	25
(Ferritin)	1	67	329	75	355	0	1243	99	92	89
(Ferritin)	2	62	322	75	355	0	574	99	87	83
(Ferritin)	3	34	79	75	355	5	513	100	99	45
(Ferritin)	4	30	243	75	355	0	490	98	88	40
(FGGY_N)_(FGGY_C)	1	24	44	32	66	0	1578	75	100	75
(Rhv)	1	65	158	87	194	0	3504	94	30	75
(Rhv)	2	65	156	87	194	0	1573	99	30	75
(Rhv)	3	55	143	87	194	0	1330	97	37	63
(Flavi_glycoprot)_(Flavi_glycop_C)	1	35	37	69	73	3	1112	76	41	51
(Flavin_Reduct)	1	28	40	30	45	9	2795	98	100	93
(Calici_coat)_(Calici_coat_C)	1	36	87	37	93	0	1708	92	93	97
(Flavodoxin_2)	1	37	99	37	140	9	1949	97	100	100
(FMN_red)	1	31	47	32	48	6	1089	96	94	97
(FMN_red)	2	25	41	32	48	6	1041	88	90	78
(FMN_red)	3	22	37	32	48	6	497	86	84	69
(Hormone_recep)_(ESR1_C)	1	23	171	23	183	0	1614	91	95	100
(RNA_pol_L)_(RNA_pol_A_bac)_(RNA_pol_L)_(RNA_pol_A_CTD)	1	32	75	32	79	0	1673	100	91	100
(PDEase_I)	1	25	92	55	254	0	768	23	12	45
(Catalase)_(Catalase-rel)	1	23	65	23	65	0	2085	95	100	100
(Catalase)_(Catalase-rel)	2	23	65	23	65	0	4374	95	100	100
(Catalase)_(Catalase-rel)	3	22	64	23	65	31	4798	98	100	96
(CBS)_(CBS)	1	28	31	46	54	6	1265	97	97	61
(RVP)	1	60	703	61	841	0	1780	99	97	98
(DNA_topoisoIV)	1	20	47	20	48	0	1501	98	77	100
(Gal-bind_lectin)	1	28	56	89	227	0	647	100	48	31
(GFO_IDH_MocA)_(GFO_IDH_MocA_C)	1	52	72	60	91	0	1654	88	96	87
(GDP_Man_Dehyd)	1	48	103	50	122	9	1174	89	100	96
(Response_reg)	1	23	39	147	241	16	946	56	36	16
(Response_reg)	2	22	44	147	241	8	465	2	0	15
(Response_reg)	3	22	43	147	241	14	550	21	28	15
(Photo_RC)	1	22	145	25	160	0	4649	100	92	88
(Glyoxalase)	1	64	104	76	128	6	2327	95	95	84
(GST_N)_(GST_C_2)	1	39	54	44	60	0	1463	96	96	89
(GST_N)_(GST_C)	1	36	49	37	50	9	1484	86	94	97
(GST_N_3)_(GST_C_2)	1	58	85	85	130	10	1396	95	93	68
(HIT)	1	28	63	28	63	7	1812	98	98	100
(Sod_Cu)	1	53	134	75	177	0	685	96	91	71
(Hydrolase_6)_(Hydrolase_like)	1	21	32	27	45	15	1172	72	97	78
(NGF)	1	20	22	20	22	0	1447	100	95	100
(IMPDH)	1	29	49	29	49	15	1927	98	100	100
(Inositol_P)	1	29	52	38	75	15	1418	94	83	76
(Isochorismatase)	1	21	29	33	44	11	1481	93	97	64
(IspD)	1	21	37	26	43	16	1802	92	92	81
(Insulin)	1	20	292	33	324	0	656	99	76	61
(IBB)_(Arm)_(Arm)_(Arm)_(HEAT_EZ)_(Arm)_(Arm)_(Arm)_(Arm)_(A rm_3)	1	22	61	25	68	0	646	0	0	88
(IBB)_(Arm)_(Arm)_(Arm)_(HEAT_EZ)_(Arm)_(Arm)_(Arm)_(Arm)_(A rm_3)	2	22	61	25	68	0	412	0	0	88
(Citrate_synt)	1	26	49	26	49	0	4744	100	94	100
(ketoacyl-synt)_(Ketoacyl-synt_C)	1	27	56	27	56	14	3167	98	100	100
(Porin_1)	1	25	52	25	53	14	1470	100	96	100
(cNMP_binding)_(HTH_Crp_2)	1	59	91	61	96	0	1873	99	97	97
(Ldh_1_N)_(Ldh_1_C)	1	93	211	98	225	10	2173	98	96	95
(Ldh_1_N)_(Ldh_1_C)	2	68	162	98	225	21	1004	96	91	69
(Ldh_1_N)_(Ldh_1_C)	3	57	139	98	225	21	1024	93	89	58
(COesterase)	1	24	128	52	347	0	917	46	80	46
(Cu-oxidase_3)_(Cu-oxidase)	1	23	141	23	150	0	1916	97	98	100
(Peptidase_C30)	1	34	113	38	119	0	1262	87	96	89
(HTH_3)	1	38	75	58	100	0	1090	96	85	66
(Lig_chan-Glu_bd)	1	50	248	72	337	0	896	85	63	69
(Lig_chan-Glu_bd)	2	23	153	72	337	52	246	1	0	32
(Transthyretin)	1	26	266	30	324	0	885	100	95	87
(Transthyretin)	2	23	263	30	324	0	400	91	90	77
(Transthyretin)	3	23	271	30	324	0	327	88	87	77
(Gp_dh_N)_(Gp_dh_C)	1	64	125	64	128	0	1968	95	95	100
(Gp_dh_N)_(Gp_dh_C)	2	61	122	64	128	0	1303	91	97	95
(Gp_dh_N)_(Gp_dh_C)	3	60	121	64	128	0	486	92	94	94
(LysR_substrate)	1	29	44	36	55	7	1377	91	100	81
(MarR)	1	37	48	42	54	9	2573	94	98	88
(MarR_2)	1	30	47	33	50	6	2613	100	98	91
(PemK_toxin)	1	22	29	22	29	0	1059	93	90	100
(TIM)	1	71	166	83	200	0	1576	98	100	86
(MIF)	1	28	95	28	99	2	1105	99	99	100
(Cpn60_TCP1)	1	61	86	81	115	0	1477	100	64	75
(Cpn60_TCP1)	2	28	37	81	115	0	582	95	30	35
(Cupin_2)	1	39	49	52	65	0	1655	98	100	75
(Cys_Met_Meta_PP)	1	30	67	30	68	0	2422	99	100	100
(Cys_Met_Meta_PP)	2	28	63	30	68	0	1574	92	98	93
(Cys_Met_Meta_PP)	3	27	64	30	68	0	846	94	98	90
(MR_MLE_N)_(MR_MLE_C)	1	103	184	138	240	0	1290	84	94	75
(MR_MLE_N)_(MR_MLE_C)	2	93	170	138	240	11	1466	86	89	67
(MR_MLE_N)_(MR_MLE_C)	3	79	139	138	240	12	560	68	86	57
(NDK)	1	56	146	56	148	27	856	92	99	100
(NDK)	2	43	126	56	148	27	714	94	75	77
(DAHP_synth_1)	1	27	119	28	148	8	1939	97	99	96
(DAHP_synth_1)	2	21	84	28	148	21	1384	92	95	75
(Dala_Dala_lig_N)_(Dala_Dala_lig_C)	1	25	44	25	44	19	1433	89	95	100
(Neur_chan_LBD)	1	48	119	54	135	0	1344	100	97	89
(Nitroreductase)	1	62	89	64	91	6	3643	100	100	97
(DegT_DnrJ_EryC1)	1	27	53	27	53	14	2409	92	100	100
(PALP)	1	67	195	87	224	0	1930	89	94	77
(NTP_transferase)	1	24	54	34	71	15	1485	81	96	71
(NUDIX)	1	28	32	105	215	10	1504	72	97	27
(GST_N)_(GST_C_3)	1	78	241	81	278	0	1319	98	95	96
(DHDPS)	1	79	164	82	179	0	1411	98	99	96
(DHDPS)	2	57	124	82	179	0	922	95	85	70
(Thymidylat_synt)	1	48	210	48	210	0	2181	94	98	100
(DJ-1_PfpI)	1	24	61	53	103	0	1353	93	100	45
(RNase_PH)_(RNase_PH_C)	1	24	40	25	41	0	1612	100	95	96
(RNase_PH)_(RNase_PH_C)	2	21	37	25	41	0	1152	100	95	84
(DNA_pol3_beta)_(DNA_pol3_beta_2)_(DNA_pol3_beta_3)	1	31	62	31	65	0	1228	100	90	100
(dUTPase)	1	35	93	39	100	15	1643	99	100	90
(DXP_reductoisom)_(DXP_redisom_C)_(DXPR_C)	1	20	66	20	67	27	1737	100	100	100
(PfkB)	1	45	73	88	160	9	1381	95	99	51
(PfkB)	2	25	35	88	160	14	1052	97	91	28
(Phos_pyr_kin)	1	22	43	22	44	14	1867	84	98	100
(polyprenyl_synt)	1	45	128	47	187	0	2560	99	99	96
(Prenyltransf)	1	20	57	20	57	11	2082	98	100	100
(Pribosyltran)	1	45	72	99	147	0	1473	94	100	45
(Pribosyltran)	2	25	34	99	147	8	1480	97	100	25
(Pro_CA)	1	22	51	22	51	10	2976	96	94	100
(PTE)	1	20	97	27	106	25	1528	78	100	74
(ECH_1)	1	114	162	129	181	0	1481	96	96	88
(ECH_1)	2	26	32	129	181	19	494	69	81	20
(Pyr_redox_2)	1	29	39	40	74	0	2125	90	97	72
(Pyridox_oxidase)	1	21	32	22	32	2	1181	97	97	95
(Thiolase_N)_(Thiolase_C)	1	37	81	41	87	0	2590	100	99	90
(Thiolase_N)_(Thiolase_C)	2	21	54	41	87	0	298	89	91	51
(Thiolase_N)_(Thiolase_C)	3	21	54	41	87	0	611	89	91	51
(Pyridoxal_deC)	1	28	41	28	41	0	5724	100	100	100
(Pyrophosphatase)	1	27	63	32	86	30	705	90	100	84
(Pyrophosphatase)	2	24	57	32	86	30	652	91	96	75
(RuBisCO_large_N)_(RuBisCO_large)	1	30	83	30	83	0	4232	99	94	100
(Ribonuc_L-PSP)	1	37	41	40	44	9	998	93	98	92
(Semialdhyde_dh)_(Semialdhyde_dhC)	1	36	70	36	70	0	2562	89	97	100
(SHMT)	1	23	74	24	75	31	3938	97	100	96
(SnoaL_2)	1	24	24	64	125	4	1155	100	100	38
(Spermine_synth)	1	20	45	20	45	14	1682	100	98	100
(SSB)	1	31	46	32	48	0	1099	91	96	97
(Thymidylate_kin)	1	24	70	31	90	17	920	77	100	77
(TP_methylase)	1	27	109	28	110	2	2378	96	96	96
(TPP_enzyme_N)_(TPP_enzyme_M)_(TPP_enzyme_C)	1	49	145	49	145	0	3463	100	100	100
(TPP_enzyme_N)_(TPP_enzyme_M)_(TPP_enzyme_C)	2	28	103	49	145	0	1422	99	99	57
(TPP_enzyme_N)_(TPP_enzyme_M)_(TPP_enzyme_C)	3	25	99	49	145	0	612	99	99	51
(Transpeptidase)	1	25	64	57	146	0	1034	88	61	44
(tRNA-synt_1b)	1	45	96	46	97	5	1714	89	100	98
(UDPG_MGDP_dh_N)_(UDPG_MGDP_dh)_(UDPG_MGDP_dh_C)	1	22	33	23	34	15	2930	100	97	96