Clusters with M>=20,SeqId<90 and single Pfam Architecture

Pfam ArchitectureCluster##CFs/Cluster#Entries/Cluster#CFs/Group#Entries/GroupMinimum Seq IdentitySurface AreaIn PDBBA(%)In PISABA(%)CFs Cluster/Group(%)
(14-3-3)1691957119681007957297
(14-3-3)221297119685990730
(Acetyltransf_1)150691632381028039610031
(Histone)18721233023913598977326
(Thioredoxin)1275215819613573407517
(2-Hacid_dh_C)16110065111102748918894
(4HBT)18514385146613089799100
(4HBT)23567851467538788241
(4HBT)328558514610269758733
(IL8)136628012010743847145
(IL8)227528012010820835234
(V-set)125136385194510806967529
(V-set)26796851945750110158
(V-set)3434985194584014165
(V-set)4202285194511299052
(Serpin)1294115220702262959519
(P-II)15071507210112710097100
(JAB)_(MitMem_reg)134347038113505972449
(Proteasome)111342612150336861007493
(Proteasome)2964041215032723997479
(Proteasome)3924041215033952997476
(Proteasome_A_N)_(Proteasome)19438695452213491007299
(ubiquitin)12326374376332950126
(ubiquitin)220243743763355638505
(ABC_membrane)_(ABC_tran)130403246114791927294
(ABM)13141435551368909872
(Iso_dh)1771827918382762989397
(Acetyltransf_3)129503760101002766878
(Collagen)12845435508881008765
(ACP_syn_III)_(ACP_syn_III_C)1489953105112660969691
(ACPS)126362636207518978100
(ACR_tran)130903192103084978697
(Actin)1737420124813735961936
(Actin)26464201248255031001432
(Actin)32438201248802550012
(MHC_I)_(C1-set)163117433849336643615
(MHC_I)_(C1-set)23710343384918481009
(MHC_I)_(C1-set)5309243384983498007
(MHC_I)_(C1-set)33516243384942290108
(MHC_I)_(C1-set)43415943384969363008
(MHC_I)_(C1-set)7216543384972278005
(MHC_I)_(C1-set)9204743384970329405
(MHC_I)_(C1-set)6243443384969293006
(MHC_I)_(C1-set)8236243384988224005
(TGF_beta)159807091101309958884
(Acyl-CoA_dh_N)_(Acyl-CoA_dh_M)_(Acyl-CoA_dh_1)163886491101796919098
(Acyl-CoA_dh_N)_(Acyl-CoA_dh_M)_(Acyl-CoA_dh_1)262876491101998899097
(Acyl-CoA_dh_N)_(Acyl-CoA_dh_M)_(Acyl-CoA_dh_1)322306491152528710034
(Adeno_knob)13051315671092947897
(ADH_N)_(ADH_zinc_N)19420998216101546939396
(ADH_N)_(ADH_zinc_N)246739821611497757547
(ADH_N)_(ADH_zinc_N)341669821611593777942
(ADH_N_2)_(ADH_zinc_N)121362544131172789484
(ADH_N_assoc)_(ADH_N)_(ADH_zinc_N)1213021301817359793100
(adh_short)1821649519282257969386
(adh_short)2222595192101265929223
(adh_short_C2)139080641288281630949395
(adh_short_C2)237980241288241479939292
(adh_short_C2)32235784128824640928954
(adh_short_C2)4203141288217315305
(OEP)_(OEP)1202721291324931009395
(Pkinase)13898692347610163460855
(Pkinase)221149692347622517103
(AhpC-TSA)_(1-cysPrx_C)159100591031818019793100
(AhpC-TSA)_(1-cysPrx_C)246845910320698947678
(Globin)19439621312589855999344
(Globin)28337821312589576957439
(Globin)364292213125827298968130
(Globin)7204721312587337494609
(Globin)5251752131258844660012
(Globin)426169213125893480012
(Globin)6221652131258853580010
(tRNA_anti-codon)_(tRNA-synt_2)134633563114203957597
(AIRS)_(AIRS_C)126422743102364889896
(Ala_racemase_N)_(Ala_racemase_C)136633866828941008395
(AlaDh_PNT_N)_(AlaDh_PNT_C)123382846241765979782
(Aldedh)1144321144329828959995100
(Aldedh)295222144329101125918666
(Aldedh)38621114432922963918660
(BTB_2)120282028178087136100
(Aldolase_II)121472248101239989495
(Lectin_legB)1722519130926952927679
(Lectin_legB)3211269130958982858523
(Lectin_legB)420709130932861896322
(Lectin_legB)226439130947878987729
(Amidohydro_1)1233886176171420799727
(Amidohydro_1)22239861761025636410026
(OTCace_N)_(OTCace)16314264166131105969998
(Aminotran_1_2)114633117240373076979485
(Aminotran_3)19924399248846589791100
(Aminotran_3)2225199248201112787822
(Aminotran_4)148965210882351989592
(Aminotran_5)1831508615472835978897
(Hormone_recep)11224343011198101142594641
(ANF_receptor)1202446821213911008843
(ANF_receptor)_(Lig_chan-Glu_bd)_(Lig_chan)1506063721420941005079
(Tubulin)_(Tubulin_C)1128233143258101457995890
(Tubulin)_(Tubulin_C)2394414325824414801827
(S_100)_(EF-hand_1)16515771166414651006392
(Trypsin)225293557222027544004
(Trypsin)129246557222032389025
(Trypsin)32460557222010282298954
(Trypsin)422224557222036255004
(EF-hand_7)_(EF-hand_7)129441982111452421615
(AP_endonuc_2)12315343179124207959353
(AP_endonuc_2)22315343179121612949253
(AP_endonuc_2)32213343179121622939051
(Copper-bind)128501052469449247227
(PIN)12024303491120968367
(Ribonuc_red_sm)1421184412392445958195
(ATP-synt_C)1547056701013371005796
(Avidin)1502645528081625969591
(Avidin)2412525528012506969375
(Avidin)3201385528015225939136
(Pkinase_Tyr)130105373151218126236488
(C1-set)_(C1-set)18617695196211110898391
(PDGF)138424044261313989095
(Bac_DNA_binding)1263926391120909782100
(Bac_luciferase)12937324082482897891
(Bac_rhodopsin)1231345924911726976639
(TNF)17093771018988908391
(Histone)_(Histone_H2A_C)1722058721769137987583
(LSM)18391869307891004797
(LSM)250538693106731002158
(LSM)44748869326661002355
(LSM)34750869398341002255
(Lipocalin)12355174544214267413
(Beta-lactamase2)12070135454143770015
(V-set)_(V-set)12735118103171214545423
(Carboxyl_trans)125412741124564989093
(Pyr_redox_2)_(Pyr_redox_dim)184173841731134009697100
(BIR)132785811222393223155
(Peptidase_C14)164250702648916729591
(Peptidase_C14)22713370264322311009639
(BMC)13958405879771008198
(BMC)2212840581426536052
(Bromodomain)1572491531105103483837
(Bromodomain)5244731531105173580016
(Bromodomain)25320015311056726122635
(Bromodomain)3281171531105143090118
(Bromodomain)4253031531105134490016
(BTB)1366436641117337380100
(bZIP_2)13099361030752938383
(GP41)1971731252090765795678
(Anoct_dimer)_(Anoctamin)12425242516227210016100
(C1q)1233423341093210091100
(V-set)_(DUF1968)148114208325246903823
(Gag_p24)234851151604428361830
(Gag_p24)13778115160101184963832
(Hemagglutinin)11894362424814644938478
(Hemagglutinin)216138024248102738978767
(Neur)13820543211131638978288
(p450)1512023049541053684617
(p450)224109304954108191398
(PNP_UDP_1)19535314245051544979167
(PNP_UDP_1)340182142450111318989628
(PNP_UDP_1)24277142450151633978430
(IgG_binding_B)12035355028442141457
(Rhv)1128230189262312761004768
(Rhv)2120211189262414471004763
(Rhv)311520918926253472994361
(Lectin_C)15791114170101403656250
(Lectin_C)2323911417010696744928
(Cadherin)_(Cadherin)124364359291029866956
(Calici_coat)_(Calici_coat_C)15113652141131742907998
(DMRL_synthase)1244824481281310090100
(NO_synthase)12161323773132565998891
(Catalase)_(Catalase-rel)1225722581242869596100
(Catalase)_(Catalase-rel)2225722581221069596100
(Catalase)_(Catalase-rel)321562258144655989695
(Peptidase_C1)128541513091846341319
(CBS)_(CBS)13538505891211879570
(DNA_topoisoIV)128592959281462987197
(PCNA_N)_(PCNA_C)16790789911659805686
(HATPase_c)_(HSP90)123342554854148971442
(Pterin_bind)12484278891286869389
(CesT)120212021813268690100
(Chal_sti_synt_N)_(Chal_sti_synt_C)1428242821126459988100
(Response_reg)1931471702595605434455
(Response_reg)33381170259154801019
(Response_reg)23849170259846881422
(Insulin)130326603790681987450
(Insulin)222215603790337455837
(Insulin)320215603790608618033
(Citrate_synt)1437344731038301007498
(Porin_1)145745274141501978987
(CLP_protease)13159326111712788697
(CLP_protease)229573261241373989191
(CutA1)1243424342011059188100
(MoCF_biosynth)12132233315750889491
(CN_hydrolase)122563174132632988271
(cNMP_binding)_(HTH_Crp_2)1651086610971871989498
(COesterase)1332436641825926567450
(Toxin_TOLIP)12427548520479373344
(Peptidase_M10)122377723749340163829
(Cu-oxidase_3)_(Cu-oxidase)126155261771019889785100
(Peptidase_C30)13712541131361264869690
(Dynein_light)12132233313929917591
(Cytochrom_C)1253411215110402186222
(Gp_dh_N)_(Gp_dh_C)184149841521219709585100
(Gp_dh_N)_(Gp_dh_C)2831498415234487928499
(Gp_dh_N)_(Gp_dh_C)38314884152341311928699
(Gp_dh_N)_(Gp_dh_C)4225184152433870026
(Phycobilisome)126663369715251009579
(Phycobilisome)2236333699508899470
(Cpn60_TCP1)1711018712491552996582
(Cpn60_TCP1)239518712410659944145
(CTP_transf_like)1238661145101114795338
(CTP_transf_like)321846114533581869234
(CTP_transf_like)222386114514990797936
(Cupin_1)_(Cupin_1)1264426451024739389100
(Cupin_2)152645264715358892100
(Cys_Met_Meta_PP)1378337841024139899100
(Cys_Met_Meta_PP)236813784201568949897
(Cys_Met_Meta_PP)33479378410841949792
(Photo_RC)142178421890474910087100
(Cytochrom_C1)12040346950291858259
(Cytochrome_B)_(Cytochrom_B_C)130543481431132897888
(Peptidase_M16)_(Peptidase_M16_C)1367243881118351008284
(Peptidase_M16)_(Peptidase_M16_C)22343438821740867953
(DAHP_synth_1)1271192812591983979796
(Dala_Dala_lig_N)_(Dala_Dala_lig_C)1284828492014348394100
(DapB_N)_(DapB_C)1233523351812549489100
(DapB_N)_(DapB_C)221322335181498948191
(DegT_DnrJ_EryC1)13360336010242692100100
(DHDPS)1941819518471426989499
(DHDPS)2721459518410911948076
(DHDPS)323299518482850024
(Thymidylat_synt)156233562421021709494100
(DHquinase_I)120332134181076949195
(DHquinase_II)126662667109028892100
(DHquinase_II)22262266713647959485
(Dimerisation)_(Methyltransf_2)1244724481141669177100
(DJ-1_PfpI)134935312591310948064
(DNA_pol3_beta)_(DNA_pol3_beta_2)_(DNA_pol3_beta_3)14482468371205968096
(Redoxin)1384856638752719068
(dTDP_sugar_isom)1213121311215509790100
(dUTPase)1531185612691655979895
(DXP_reductoisom)_(DXP_redisom_C)_(DXPR_C)122722276271726100100100
(ECH_1)115120115220271500989299
(ECH_1)277981522027829727851
(ECH_1)35574152202121209828536
(ECH_1)42441152202104420216
(Thiolase_N)_(Thiolase_C)15311056116102519998695
(Thiolase_N)_(Thiolase_C)229685611631304908152
(Thiolase_N)_(Thiolase_C)329685611631632908152
(RNase_PH)_(RNase_PH_C)1294630481115931008797
(RNase_PH)_(RNase_PH_C)22744304891139988490
(ELFV_dehydrog_N)_(ELFV_dehydrog)1396339631113429470100
(ELFV_dehydrog_N)_(ELFV_dehydrog)2345439631613701006987
(ELFV_dehydrog_N)_(ELFV_dehydrog)33151396314422986779
(Enolase_N)_(Enolase_C)1378037801118219592100
(Enterotoxin_b)1255926591512711009396
(Epimerase)134676110581313859656
(F_bP_aldolase)12152215217212210098100
(FabA)125502651713831009496
(RnaseA)123203108427143501121
(FBPase)122135221481421839283100
(FBPase)22012822148141159887791
(Fe-ADH)1283528351114578683100
(Ferritin)110641411144131248998395
(Ferritin)21014071114414578998091
(Ferritin)3983971114414501998288
(FGGY_N)_(FGGY_C)127503468151524709479
(TLV_coat)12541284301234856189
(FKBP_C)1202912214513508246616
(Flavi_glycoprot)_(Flavi_glycop_C)1545810996271127833350
(Flavi_glycoprot)_(Flavi_glycop_C)22121109963668581519
(Flavin_Reduct)1314631467281598100100
(Flavodoxin_2)140126401301019639898100
(IBB)_(Arm)_(Arm)_(Arm)_(Arm)_(Arm)_(Arm)_(Arm)_(Arm)_(Arm_3 )1248245100474150053
(FMN_dh)122562356121519868896
(FMN_red)13551365291120969097
(FMN_red)228423652101109869078
(FMN_red)32539365210593878769
(Lys)12459616613613556311014
(FUR)121272228161516968195
(Fusion_gly)13561407402145989888
(RVP)16376166955131791999395
(RVP)23154966955262490047
(RVP)32216066955192390033
(Gal-bind_lectin)1461039528210627855348
(Gal-bind_lectin)223509528211678506024
(Gal-bind_lectin)3215295282133618422
(GP120)22664190257684520214
(GP120)1315219025769411852716
(GDP_Man_Dehyd)1459045911111208996100
(GFO_IDH_MocA)_(GFO_IDH_MocA_C)149855188101636868796
(GFO_IDH_MocA)_(GFO_IDH_MocA_C)22147518812611835741
(GFP)116329424464581103515867
(GFP)28718424464513849585736
(GFP)33454244645113272014
(GFP)43349244645103898414
(GFP)5243324464515317151210
(GFP)62431244645183970010
(Glycolytic)1226423661512811009596
(Glyoxalase)1821328313382254898399
(Glyoxalase)2212483133831702125
(GST_N)_(GST_C)156735774111518899098
(GST_N)_(GST_C_3)18826892297101325969296
(GST_N)_(GST_C_2)12339233991352100100100
(GST_N_3)_(GST_C)13854435881299948388
(GST_N_3)_(GST_C_2)1457271113111366936863
(HTH_3)136716410281114969056
(HSP20)124304558101446979053
(Hfq)121592159875610093100
(His_Phos_1)120415711642884903935
(HIT)1339033908187210096100
(Sod_Cu)1561488819923682948364
(HTH_1)_(LysR_substrate)12736314071449898987
(IF-2B)1213623381420641007891
(NGF)12022202243145095100100
(IMPDH)140814284172086998995
(Inositol_P)136684590151416966380
(Ion_trans)126913798617001007370
(Isochorismatase)127423857101543959071
(IspD)1204120412017509393100
(Jacalin)127744310621551898463
(ketoacyl-synt)_(Ketoacyl-synt_C)126602763143171989396
(ketoacyl-synt)_(Ketoacyl-synt_C)_(KAsynt_C_assoc)123472547172691969692
(LAGLIDADG_1)1224522451391310080100
(Ldh_1_N)_(Ldh_1_C)1112244116250102198988997
(Ldh_1_N)_(Ldh_1_C)280187116250121009958369
(Ldh_1_N)_(Ldh_1_C)367162116250101066948158
(Lyase_1)_(FumaraseC_C)1243224323623719797100
(Lyase_1)_(FumaraseC_C)2243224323618599797100
(Lyase_1)_(FumaraseC_C)3243224323629839797100
(LysR_substrate)13857477291355938881
(MarR)143574963102477959188
(MarR_2)124322735926431009789
(PemK_toxin)1263326331210469494100
(Methyltransf_3)1282957141132018909349
(MIF)129117291341111059894100
(MIP)130463652171688989383
(MR_MLE_N)_(MR_MLE_C)114223718029781293819579
(MR_MLE_N)_(MR_MLE_C)213222018029791695899273
(MR_MLE_N)_(MR_MLE_C)31161911802978633659064
(NAD_binding_2)_(NAD_binding_11)120333554152433887057
(NDK)17716177168278569398100
(NDK)2611357716827706937379
(Neur_chan_LBD)15614966164713611008985
(Neur_chan_LBD)2285866164303270042
(Neur_chan_LBD)_(Neur_chan_memb)153162561661022501007295
(Nitroreductase)172103721035376710095100
(PALP)18524110829691896898679
(NTP_transferase)130654387171486829470
(NUDIX)13038133416111321718723
(OMPdecase)154232542561017349698100
(OsmC)124282529831001009396
(PA-IIL)1206120613413208480100
(PDEase_I)1321866235221757191652
(Peptidase_M20)_(M20_dimer)_(Peptidase_M20)1222829361021061009676
(PfkB)1529598189101376938753
(PfkB)2253698189141049978926
(PGI)12253225315613694100100
(Phos_pyr_kin)121432446141871819888
(PK)_(PK_C)146884789211164978698
(PK)_(PK_C)246884789212485989498
(polyprenyl_synt)1812688229512207969799
(Prenyltransf)1267326741119639995100
(Pribosyltran)15094122204121477969741
(Pribosyltran)2446712220481418977836
(Pribosyltran)3213212220410648442217
(Pro_CA)1245724571029878991100
(PTE)12515032169251483837778
(Pyr_redox_2)1547475128102079928572
(Putative_PNPOx)12133223321193979795
(Pyridoxal_deC)1344735481057781008797
(Pyrophosphatase)12767379230702919973
(Pyrophosphatase)22564379230649849568
(RuBisCO_large_N)_(RuBisCO_large)14794489794114989198
(RuBisCO_large_N)_(RuBisCO_large)23058489733472977662
(RuBisCO_large_N)_(RuBisCO_large)32957489733468967960
(Ribonuc_L-PSP)14246454912995939193
(RNA_pol_L)_(RNA_pol_A_bac)_(RNA_pol_L)_(RNA_pol_A_CTD)1701417014429172810075100
(Semialdhyde_dh)_(Semialdhyde_dhC)138733875925678897100
(SHMT)131104311061340589788100
(SnoaL_2)2268478141121033909033
(SnoaL_2)136397814161083879246
(Sod_Fe_N)_(Sod_Fe_C)171151771589884958992
(Spike_NTD)_(Spike_rec_bind)_(Corona_S2)1323233332127541001297
(SpoU_methylase)12025202515141710096100
(SSB)141614161711229380100
(SSB)2223041617417574754
(Sulfotransfer_1)1255040732137112062
(TGT)12113524158231541759288
(Thymidylate_kin)130983712213950829781
(TIM)1811859721281577989684
(TMEM173)121442346617191007091
(TP_methylase)1321193312772731979197
(TPP_enzyme_N)_(TPP_enzyme_M)_(TPP_enzyme_C)154163541641134659992100
(TPP_enzyme_N)_(TPP_enzyme_M)_(TPP_enzyme_C)2279854164161413999750
(TPP_enzyme_N)_(TPP_enzyme_M)_(TPP_enzyme_C)325945416416617999846
(Transpeptidase)1301136722710995586745
(Transthyretin)14833552458188841009492
(Transthyretin)2453315245818399928987
(Transthyretin)3453305245818334928987
(Transthyretin)42529952458514140048
(tRNA-synt_1b)1541075510871703879798
(tRNA-synt_2b)_(HGTP_anticodon)1254025408265010095100
(tRNA-synt_2b)_(HGTP_anticodon)_(ProRS-C_1)1213621362222948394100
(UDPG_MGDP_dh_N)_(UDPG_MGDP_dh)_(UDPG_MGDP_dh_C)1243924391128799787100
(YgbB)121632168261028100100100
(Lig_chan-Glu_bd)_(Lig_chan)1452727133815910856063
(Lig_chan-Glu_bd)_(Lig_chan)22115771338482831030
(TetR_N)_(TetR_C_1)1346834681524369788100
(TetR_N)_(TetR_C_24)12829282910143310097100
(AAA)_(AAA_lid_3)12735604421102637945
(Asparaginase)_(Asparaginase_C)13050305017213810098100
(Asparaginase)_(Asparaginase_C)22746305017946989890
(Asparaginase)_(Asparaginase_C)322393050439981009773
(Clp_N)_(Clp_N)_(AAA)_(AAA_lid_9)_(AAA_2)_(ClpB_D2-small)128293132292724901490
(V-set)_(C1-set)11911246644563138016991008543
(V-set)_(C1-set)2114713954456313873782526
(V-set)_(C1-set)3103413634456313853832623
(V-set)_(C1-set)4452614445631381372101010
(V-set)_(C1-set)51842194456313810322444
(V-set)_(C1-set)6215287445631383353245
(V-set)_(C1-set)725304456313813356001
(V-set)_(C1-set)820734456313814354000