• Overview

    ProtCAD is a comprehensive database of protein assemblies in PDB. It uses EPPIC assemblies and PDB biological assemblies which are not defined in EPPIC, groups assemblies with same Pfam architectures, and clusters assemblies in same stoichiometry, same symmetry and similar interfaces. A cluster contains multiple numbers including the number of distinct crystal forms (#CFs_clus), the number of entries (#ENT_clus), minimum sequence identity of assembly sequences, the number of unique UniProts (#UNP_clus), the number of crystal forms of these UniProts in a cluster (#CFs_UNPclus), the number of crystal forms of these same UniProts in a Pfam architecture (#CFs_UNParch), the ratio between #CFs_UNPclus and #CFs_UNParch (R_CF_UNPclus), the number of PDB entries which contain PDB biological assemblies which are same as the cluster (#PDBBAs), the ratio between #PDBBAs and #ENT_clus (R_PDB), the number of PISA assemblies which are same as the cluster (#PISABAs), the ratio between #PISABAs and #ENT_clus (R_PISA), and the number of EPPIC predicted biological assemblies which are same as the cluster (#EPPICBAs), the ratio between #EPPICBAs and #ENT_clus (R_EPPIC). These numbers can be combined to provide evidences to identify biological assemblies.

  • Search

    ProtCAD can searched by PDB IDs, Pfams and UniProts.

  • Browse

    Pfams, Pfam architectures and Uniprots in PDB can be browsed.

  • Download

    All coordinates of assemblies of clusters can be downloaded. Clusters text files can also be downloaded.

  • Glossary

    The important terms used in ProtCAD are explained here.