PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 7TCQ

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	heavy	Mus.musculus	Mo_IGHV1-5*01	91.8	Mo_IGHV1-5*01	76.9	H1	13	H1-13-1	6	KASGYTFTNYWIH	BBBLBBAAABBBB
A	heavy	Mus.musculus	Mo_IGHV1-5*01	91.8	Mo_IGHV1-5*01	60.0	H2	10	H2-10-1	14	GTYPGNGDTT	BBBAAALBBB
A	heavy	Mus.musculus	Mo_IGHV1-5*01	91.8	Mo_IGHV1-5*01	100.0	H3	9	H3-9-2	13	TRTGSYFDY	BBBAABBAB
A	heavy	Mus.musculus	Mo_IGHV1-5*01	91.8	Mo_IGHV1-5*01	75.0	H4	8	H4-8-1	7	AVTPTSTA	BBAAALBB
B	kappa	Mus.musculus	Mo_IGKV4-61*01	95.7	Mo_IGKV4-61*01	80.0	L1	10	L1-10-1	6	SATSSVSYIY	BBABBBABBB
B	kappa	Mus.musculus	Mo_IGKV4-61*01	95.7	Mo_IGKV4-61*01	100.0	L2	8	L2-8-1	6	YRTSNLAS	BLLABBBB
B	kappa	Mus.musculus	Mo_IGKV4-61*01	95.7	Mo_IGKV4-61*01	87.5	L3	9	L3-9-cis7-1	16	QQYQSYPPT	BBAABBbBB
B	kappa	Mus.musculus	Mo_IGKV4-61*01	95.7	Mo_IGKV4-61*01	100.0	L4	6	L4-6-1	12	GSGTSY	EEEABB
H	heavy	Mus.musculus	Mo_IGHV1-5*01	91.8	Mo_IGHV1-5*01	76.9	H1	13	H1-13-1	6	KASGYTFTNYWIH	BBBLBBAAABBBB
H	heavy	Mus.musculus	Mo_IGHV1-5*01	91.8	Mo_IGHV1-5*01	60.0	H2	10	H2-10-1	14	GTYPGNGDTT	BBBAAALBBB
H	heavy	Mus.musculus	Mo_IGHV1-5*01	91.8	Mo_IGHV1-5*01	100.0	H3	9	H3-9-2	16	TRTGSYFDY	BBBAABBAB
H	heavy	Mus.musculus	Mo_IGHV1-5*01	91.8	Mo_IGHV1-5*01	75.0	H4	8	H4-8-1	7	AVTPTSTA	BBAAALBB
L	kappa	Mus.musculus	Mo_IGKV4-61*01	95.7	Mo_IGKV4-61*01	80.0	L1	10	L1-10-1	6	SATSSVSYIY	BBABBBABBB
L	kappa	Mus.musculus	Mo_IGKV4-61*01	95.7	Mo_IGKV4-61*01	100.0	L2	8	L2-8-1	7	YRTSNLAS	BLLABBBB
L	kappa	Mus.musculus	Mo_IGKV4-61*01	95.7	Mo_IGKV4-61*01	87.5	L3	9	L3-9-cis7-1	13	QQYQSYPPT	BBAABBbBB
L	kappa	Mus.musculus	Mo_IGKV4-61*01	95.7	Mo_IGKV4-61*01	100.0	L4	6	L4-6-1	11	GSGTSY	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022