PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 6PK8

#CDRs = 8; #Clusters = 10.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	95.6	Rb_IGHV1S69*01	69.2	H1	13	H1-13-1	15	TVSGFSLNTYSMF	BBBLBBAAABBBB
A	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	95.6	Rb_IGHV1S69*01	55.6	H2	9	H2-9-1	10	IISNFGVIY	BBBAALBBB
A	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	95.6	Rb_IGHV1S69*01	50.0	H3	12	H3-12-*	-1	VRKYGSEWGGDL	BBBBAABABBAB
A	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	95.6	Rb_IGHV1S69*01	100.0	H4	6	H4-6-1	8	KTSTTV	BBAABB
A	kappa	Oryctolagus.cuniculus	Rb_IGKV1S49*01	89.4	Rb_IGKV1S49*01	81.8	L1	11	L1-11-1	9	QASQSISSYLA	BBABBAEABBB
A	kappa	Oryctolagus.cuniculus	Rb_IGKV1S49*01	89.4	Rb_IGKV1S49*01	75.0	L2	8	L2-8-1	5	YETSTLAS	BLEABBBB
A	kappa	Oryctolagus.cuniculus	Rb_IGKV1S49*01	89.4	Rb_IGKV1S49*01	9.1	L3	11	L3-11-*	-1	QSTYENPtyVS	BBABBBAAABB
A	kappa	Oryctolagus.cuniculus	Rb_IGKV1S49*01	89.4	Rb_IGKV1S49*01	83.3	L4	6	L4-6-1	11	GSGTEF	EBEABB
B	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	95.6	Rb_IGHV1S69*01	69.2	H1	13	H1-13-1	15	TVSGFSLNTYSMF	BBBLBBAAABBBB
B	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	95.6	Rb_IGHV1S69*01	55.6	H2	9	H2-9-1	10	IISNFGVIY	BBBAALBBB
B	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	95.6	Rb_IGHV1S69*01	50.0	H3	12	H3-12-*	-1	VRKYGSEWGGDL	BBBBAABABBAB
B	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	95.6	Rb_IGHV1S69*01	100.0	H4	6	H4-6-1	8	KTSTTV	BBAABB
B	kappa	Oryctolagus.cuniculus	Rb_IGKV1S49*01	89.4	Rb_IGKV1S49*01	81.8	L1	11	L1-11-1	8	QASQSISSYLA	BBABBAEABBB
B	kappa	Oryctolagus.cuniculus	Rb_IGKV1S49*01	89.4	Rb_IGKV1S49*01	75.0	L2	8	L2-8-1	5	YETSTLAS	BLEABBBB
B	kappa	Oryctolagus.cuniculus	Rb_IGKV1S49*01	89.4	Rb_IGKV1S49*01	9.1	L3	11	L3-11-*	-1	QSTYENPtyVS	BBABBBAAABB
B	kappa	Oryctolagus.cuniculus	Rb_IGKV1S49*01	89.4	Rb_IGKV1S49*01	83.3	L4	6	L4-6-1	10	GSGTEF	EBEABB
C	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	95.6	Rb_IGHV1S69*01	69.2	H1	13	H1-13-1	14	TVSGFSLNTYSMF	BBBLBBAAABBBB
C	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	95.6	Rb_IGHV1S69*01	55.6	H2	9	H2-9-1	10	IISNFGVIY	BBBAALBBB
C	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	95.6	Rb_IGHV1S69*01	50.0	H3	12	H3-12-*	-1	VRKYGSEWGGDL	BBBBAABABBAB
C	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	95.6	Rb_IGHV1S69*01	100.0	H4	6	H4-6-1	7	KTSTTV	BBAABB
C	kappa	Oryctolagus.cuniculus	Rb_IGKV1S49*01	89.4	Rb_IGKV1S49*01	81.8	L1	11	L1-11-1	9	QASQSISSYLA	BBABBAEABBB
C	kappa	Oryctolagus.cuniculus	Rb_IGKV1S49*01	89.4	Rb_IGKV1S49*01	75.0	L2	8	L2-8-1	5	YETSTLAS	BLEABBBB
C	kappa	Oryctolagus.cuniculus	Rb_IGKV1S49*01	89.4	Rb_IGKV1S49*01	9.1	L3	11	L3-11-*	-1	QSTYENPtyVS	BBABBBAAABB
C	kappa	Oryctolagus.cuniculus	Rb_IGKV1S49*01	89.4	Rb_IGKV1S49*01	83.3	L4	6	L4-6-1	10	GSGTEF	EBEABB
D	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	95.6	Rb_IGHV1S69*01	69.2	H1	13	H1-13-1	15	TVSGFSLNTYSMF	BBBLBBAAABBBB
D	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	95.6	Rb_IGHV1S69*01	55.6	H2	9	H2-9-1	10	IISNFGVIY	BBBAALBBB
D	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	95.6	Rb_IGHV1S69*01	50.0	H3	12	H3-12-*	-1	VRKYGSEWGGDL	BBBBBAABBEBB
D	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	95.6	Rb_IGHV1S69*01	100.0	H4	6	H4-6-1	9	KTSTTV	BBAABB
D	kappa	Oryctolagus.cuniculus	Rb_IGKV1S49*01	89.4	Rb_IGKV1S49*01	81.8	L1	11	L1-11-*	-1	QASQSISSYLA	BBABEBBABBB
D	kappa	Oryctolagus.cuniculus	Rb_IGKV1S49*01	89.4	Rb_IGKV1S49*01	75.0	L2	8	L2-8-1	5	YETSTLAS	BLEABBBB
D	kappa	Oryctolagus.cuniculus	Rb_IGKV1S49*01	89.4	Rb_IGKV1S49*01	9.1	L3	11	L3-11-*	-1	QSTYENPtyVS	BBBBAABBBBB
D	kappa	Oryctolagus.cuniculus	Rb_IGKV1S49*01	89.4	Rb_IGKV1S49*01	83.3	L4	6	L4-6-*	-1	GSGTEF	EALABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022