PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 6CWD

#CDRs = 8; #Clusters = 9.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	heavy	Oryctolagus.cuniculus	Rb_IGHV1S44*01	83.1	Rb_IGHV1S44*01	69.2	H1	13	H1-13-1	16	TVSGIDLSSNAIS	BBBLBBAAABBBB
A	heavy	Oryctolagus.cuniculus	Rb_IGHV1S44*01	83.1	Rb_IGHV1S44*01	33.3	H2	9	H2-9-1	22	IIYGGSIPY	BBBAALBBB
A	heavy	Oryctolagus.cuniculus	Rb_IGHV1S44*01	83.1	Rb_IGHV1S44*01	50.0	H3	17	H3-17-*	-1	ARGKSDgdgYAAYRLDP
A	heavy	Oryctolagus.cuniculus	Rb_IGHV1S44*01	83.1	Rb_IGHV1S44*01	0.0	H4	6	H4-6-1	10	KTSTTV	BBAABB
A	kappa	Oryctolagus.cuniculus	Rb_IGKV1S3*01	91.0	Rb_IGKV1S3*01	72.7	L1	11	L1-11-1	22	QASQSISSRLG	BBABBAEAABB
A	kappa	Oryctolagus.cuniculus	Rb_IGKV1S3*01	91.0	Rb_IGKV1S3*01	75.0	L2	8	L2-8-*	-1	YGASTLTS	BLLABBBA
A	kappa	Oryctolagus.cuniculus	Rb_IGKV1S3*01	91.0	Rb_IGKV1S3*01	0.0	L3	10	L3-10-*	-1	LGSDtSTDTA	BBBABAABBB
A	kappa	Oryctolagus.cuniculus	Rb_IGKV1S3*01	91.0	Rb_IGKV1S3*01	83.3	L4	6	L4-6-1	24	GSGTEF	EBEABB
B	heavy	Oryctolagus.cuniculus	Rb_IGHV1S44*01	83.1	Rb_IGHV1S44*01	69.2	H1	13	H1-13-1	14	TVSGIDLSSNAIS	BBBLBBAAABBBB
B	heavy	Oryctolagus.cuniculus	Rb_IGHV1S44*01	83.1	Rb_IGHV1S44*01	33.3	H2	9	H2-9-1	19	IIYGGSIPY	BBBAALBBB
B	heavy	Oryctolagus.cuniculus	Rb_IGHV1S44*01	83.1	Rb_IGHV1S44*01	50.0	H3	17	H3-17-*	-1	ARGKSDgdgYAAYRLDP
B	heavy	Oryctolagus.cuniculus	Rb_IGHV1S44*01	83.1	Rb_IGHV1S44*01	0.0	H4	6	H4-6-1	11	KTSTTV	BBAABB
B	kappa	Oryctolagus.cuniculus	Rb_IGKV1S3*01	91.0	Rb_IGKV1S3*01	72.7	L1	11	L1-11-1	17	QASQSISSRLG	BBABBAEAABB
B	kappa	Oryctolagus.cuniculus	Rb_IGKV1S3*01	91.0	Rb_IGKV1S3*01	75.0	L2	8	L2-8-*	-1	YGASTLTS	BLLABBBA
B	kappa	Oryctolagus.cuniculus	Rb_IGKV1S3*01	91.0	Rb_IGKV1S3*01	0.0	L3	10	L3-10-*	-1	LGSDtSTDTA	BBBABAABBB
B	kappa	Oryctolagus.cuniculus	Rb_IGKV1S3*01	91.0	Rb_IGKV1S3*01	83.3	L4	6	L4-6-1	21	GSGTEF	EBEABB
E	heavy	Oryctolagus.cuniculus	Rb_IGHV1S44*01	83.1	Rb_IGHV1S44*01	69.2	H1	13	H1-13-1	15	TVSGIDLSSNAIS	BBBLBBAAABBBB
E	heavy	Oryctolagus.cuniculus	Rb_IGHV1S44*01	83.1	Rb_IGHV1S44*01	33.3	H2	9	H2-9-1	20	IIYGGSIPY	BBBAALBBB
E	heavy	Oryctolagus.cuniculus	Rb_IGHV1S44*01	83.1	Rb_IGHV1S44*01	50.0	H3	17	H3-17-*	-1	ARGKSDgdgYAAYRLDP
E	heavy	Oryctolagus.cuniculus	Rb_IGHV1S44*01	83.1	Rb_IGHV1S44*01	0.0	H4	6	H4-6-1	11	KTSTTV	BBAABB
E	kappa	Oryctolagus.cuniculus	Rb_IGKV1S3*01	91.0	Rb_IGKV1S3*01	72.7	L1	11	L1-11-1	19	QASQSISSRLG	BBABBAEAABB
E	kappa	Oryctolagus.cuniculus	Rb_IGKV1S3*01	91.0	Rb_IGKV1S3*01	75.0	L2	8	L2-8-1	25	YGASTLTS	BLLABBBB
E	kappa	Oryctolagus.cuniculus	Rb_IGKV1S3*01	91.0	Rb_IGKV1S3*01	0.0	L3	10	L3-10-*	-1	LGSDtSTDTA	BBBABAABBB
E	kappa	Oryctolagus.cuniculus	Rb_IGKV1S3*01	91.0	Rb_IGKV1S3*01	83.3	L4	6	L4-6-1	20	GSGTEF	EBEABB
G	heavy	Oryctolagus.cuniculus	Rb_IGHV1S44*01	83.1	Rb_IGHV1S44*01	69.2	H1	13	H1-13-1	14	TVSGIDLSSNAIS	BBBLBBAAABBBB
G	heavy	Oryctolagus.cuniculus	Rb_IGHV1S44*01	83.1	Rb_IGHV1S44*01	33.3	H2	9	H2-9-1	20	IIYGGSIPY	BBBAALBBB
G	heavy	Oryctolagus.cuniculus	Rb_IGHV1S44*01	83.1	Rb_IGHV1S44*01	50.0	H3	17	H3-17-*	-1	ARGKSDgdgYAAYRLDP
G	heavy	Oryctolagus.cuniculus	Rb_IGHV1S44*01	83.1	Rb_IGHV1S44*01	0.0	H4	6	H4-6-1	12	KTSTTV	BBAABB
G	kappa	Oryctolagus.cuniculus	Rb_IGKV1S3*01	91.0	Rb_IGKV1S3*01	72.7	L1	11	L1-11-1	23	QASQSISSRLG	BBABBAEAABB
G	kappa	Oryctolagus.cuniculus	Rb_IGKV1S3*01	91.0	Rb_IGKV1S3*01	75.0	L2	8	L2-8-*	-1	YGASTLTS	BLLABBBA
G	kappa	Oryctolagus.cuniculus	Rb_IGKV1S3*01	91.0	Rb_IGKV1S3*01	0.0	L3	10	L3-10-*	-1	LGSDtSTDTA	BBBABAABBB
G	kappa	Oryctolagus.cuniculus	Rb_IGKV1S3*01	91.0	Rb_IGKV1S3*01	83.3	L4	6	L4-6-1	29	GSGTEF	EBLABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022