PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 6CSF

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	heavy	Mus.musculus	Mo_IGHV6-6*01	95.9	Mo_IGHV6-6*01	76.9	H1	13	H1-13-1	13	AASGFTSSDFAMD	BBBLBBAAABBBB
A	heavy	Mus.musculus	Mo_IGHV6-6*01	95.9	CDRLenMismatch	-1.0	H2	8	H2-8-*	-1	EIAASERH
A	heavy	Mus.musculus	Mo_IGHV6-6*01	95.9	Mo_IGHV6-6*01	100.0	H3	9	H3-9-2	21	TRTAGACGQ	BBBAABBAB
A	heavy	Mus.musculus	Mo_IGHV6-6*01	95.9	Mo_IGHV6-6*01	100.0	H4	8	H4-8-1	9	RDDSKSSV	BBAAALBB
B	kappa	Mus.musculus	Mo_IGKV12-44*01	95.7	Mo_IGKV12-44*01	72.7	L1	11	L1-11-1	10	RTSENIASALA	BBABBAEABBB
B	kappa	Mus.musculus	Mo_IGKV12-44*01	95.7	Mo_IGKV12-44*01	75.0	L2	8	L2-8-1	15	MNAKTLAA	BLEABBBB
B	kappa	Mus.musculus	Mo_IGKV12-44*01	95.7	Mo_IGKV12-44*01	42.9	L3	9	L3-9-*	-1	QHAAGWLLT	BBABEABBB
B	kappa	Mus.musculus	Mo_IGKV12-44*01	95.7	Mo_IGKV12-44*01	83.3	L4	6	L4-6-1	15	GSGTAF	EBEABB
H	heavy	Mus.musculus	Mo_IGHV6-6*01	95.9	Mo_IGHV6-6*01	76.9	H1	13	H1-13-1	13	AASGFTSSDFAMD	BBBLBBAAABBBB
H	heavy	Mus.musculus	Mo_IGHV6-6*01	95.9	CDRLenMismatch	-1.0	H2	8	H2-8-*	-1	EIAASERH
H	heavy	Mus.musculus	Mo_IGHV6-6*01	95.9	Mo_IGHV6-6*01	100.0	H3	9	H3-9-2	21	TRTAGACGQ	BBBEABBAB
H	heavy	Mus.musculus	Mo_IGHV6-6*01	95.9	Mo_IGHV6-6*01	100.0	H4	8	H4-8-1	9	RDDSKSSV	BBAAALBB
L	kappa	Mus.musculus	Mo_IGKV12-44*01	95.7	Mo_IGKV12-44*01	72.7	L1	11	L1-11-1	10	RTSENIASALA	BBABBAEABBB
L	kappa	Mus.musculus	Mo_IGKV12-44*01	95.7	Mo_IGKV12-44*01	75.0	L2	8	L2-8-1	15	MNAKTLAA	BLEABBBB
L	kappa	Mus.musculus	Mo_IGKV12-44*01	95.7	Mo_IGKV12-44*01	42.9	L3	9	L3-9-*	-1	QHAAGWLLT	BBABEABBB
L	kappa	Mus.musculus	Mo_IGKV12-44*01	95.7	Mo_IGKV12-44*01	83.3	L4	6	L4-6-1	14	GSGTAF	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022