PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 5VTA

#CDRs = 8; #Clusters = 14.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
E	kappa	Mus.musculus	Mo_IGKV4-72*01	94.2	Mo_IGKV4-72*01	80.0	L1	10	L1-10-1	11	RASSSVCNMH	BBABBBABBB
E	kappa	Mus.musculus	Mo_IGKV4-72*01	94.2	Mo_IGKV4-72*01	75.0	L2	8	L2-8-1	13	HGTSNLAS	BLEABBBB
E	kappa	Mus.musculus	Mo_IGKV4-72*01	94.2	Mo_IGKV4-72*01	75.0	L3	9	L3-9-cis7-1	12	QQWSNHPPT	BBAABBbBB
E	kappa	Mus.musculus	Mo_IGKV4-72*01	94.2	Mo_IGKV4-72*01	83.3	L4	6	L4-6-1	23	GSGTSF	EBEABB
F	heavy	Mus.musculus	Mo_IGHV1-39*01	95.8	Mo_IGHV1-39*01	92.3	H1	13	H1-13-1	9	KASGYSFTDYNIN	BBBLBBAAABBBB
F	heavy	Mus.musculus	Mo_IGHV1-39*01	95.8	Mo_IGHV1-39*01	60.0	H2	10	H2-10-1	9	VVIPKYGTTN	BBBAAALBBB
F	heavy	Mus.musculus	Mo_IGHV1-39*01	95.8	Mo_IGHV1-39*01	50.0	H3	9	H3-9-*	-1	TRFRVFFDV	BBBBLBBAB
F	heavy	Mus.musculus	Mo_IGHV1-39*01	95.8	Mo_IGHV1-39*01	100.0	H4	8	H4-8-1	8	VDQSSSTA	BBAAALBB
G	kappa	Mus.musculus	Mo_IGKV4-72*01	94.2	Mo_IGKV4-72*01	80.0	L1	10	L1-10-1	16	RASSSVCNMH	BBABBBABBB
G	kappa	Mus.musculus	Mo_IGKV4-72*01	94.2	Mo_IGKV4-72*01	75.0	L2	8	L2-8-4	24	HGTSNLAS	BEAABBBB
G	kappa	Mus.musculus	Mo_IGKV4-72*01	94.2	Mo_IGKV4-72*01	75.0	L3	9	L3-9-cis7-1	13	QQWSNHPPT	BBAABBbBB
G	kappa	Mus.musculus	Mo_IGKV4-72*01	94.2	Mo_IGKV4-72*01	83.3	L4	6	L4-6-1	17	GSGTSF	EBEABB
H	heavy	Mus.musculus	Mo_IGHV1-39*01	95.8	Mo_IGHV1-39*01	92.3	H1	13	H1-13-1	15	KASGYSFTDYNIN	BBBLBBAAABBBB
H	heavy	Mus.musculus	Mo_IGHV1-39*01	95.8	Mo_IGHV1-39*01	60.0	H2	10	H2-10-1	11	VVIPKYGTTN	BBBAAALBBB
H	heavy	Mus.musculus	Mo_IGHV1-39*01	95.8	Mo_IGHV1-39*01	50.0	H3	9	H3-9-*	-1	TRFRVFFDV	BBBBEBBAB
H	heavy	Mus.musculus	Mo_IGHV1-39*01	95.8	Mo_IGHV1-39*01	100.0	H4	8	H4-8-1	7	VDQSSSTA	BBAAALBB
I	heavy	Mus.musculus	Mo_IGHV1-39*01	95.8	Mo_IGHV1-39*01	92.3	H1	13	H1-13-1	13	KASGYSFTDYNIN	BBBLBBAAABBBB
I	heavy	Mus.musculus	Mo_IGHV1-39*01	95.8	Mo_IGHV1-39*01	60.0	H2	10	H2-10-1	12	VVIPKYGTTN	BBBAAALBBB
I	heavy	Mus.musculus	Mo_IGHV1-39*01	95.8	Mo_IGHV1-39*01	50.0	H3	9	H3-9-2	22	TRFRVFFDV	BBBAABBAB
I	heavy	Mus.musculus	Mo_IGHV1-39*01	95.8	Mo_IGHV1-39*01	100.0	H4	8	H4-8-1	13	VDQSSSTA	BBAAALBB
J	kappa	Mus.musculus	Mo_IGKV4-72*01	94.2	Mo_IGKV4-72*01	80.0	L1	10	L1-10-1	10	RASSSVCNMH	BBABBBABBB
J	kappa	Mus.musculus	Mo_IGKV4-72*01	94.2	Mo_IGKV4-72*01	75.0	L2	8	L2-8-1	10	HGTSNLAS	BLEABBBB
J	kappa	Mus.musculus	Mo_IGKV4-72*01	94.2	Mo_IGKV4-72*01	75.0	L3	9	L3-9-cis7-1	11	QQWSNHPPT	BBAABBbBB
J	kappa	Mus.musculus	Mo_IGKV4-72*01	94.2	Mo_IGKV4-72*01	83.3	L4	6	L4-6-1	26	GSGTSF	EBEABB
K	heavy	Mus.musculus	Mo_IGHV1-39*01	95.8	Mo_IGHV1-39*01	92.3	H1	13	H1-13-*	-1	KASGYSFTdyNIN
K	heavy	Mus.musculus	Mo_IGHV1-39*01	95.8	Mo_IGHV1-39*01	60.0	H2	10	H2-10-*	-1	VVIPKYGTTN	BBBAABABBB
K	heavy	Mus.musculus	Mo_IGHV1-39*01	95.8	Mo_IGHV1-39*01	50.0	H3	9	H3-9-*	-1	TRFRVFFDV	BBBBLBBAB
K	heavy	Mus.musculus	Mo_IGHV1-39*01	95.8	Mo_IGHV1-39*01	100.0	H4	8	H4-8-*	-1	VDQSSSTA	BBAABBBB
L	kappa	Mus.musculus	Mo_IGKV4-72*01	94.2	Mo_IGKV4-72*01	80.0	L1	10	L1-10-1	10	RASSSVCNMH	BBABBBABBB
L	kappa	Mus.musculus	Mo_IGKV4-72*01	94.2	Mo_IGKV4-72*01	75.0	L2	8	L2-8-*	-1	HGTSNLAS	BLEABBBE
L	kappa	Mus.musculus	Mo_IGKV4-72*01	94.2	Mo_IGKV4-72*01	75.0	L3	9	L3-9-cis7-1	12	QQWSNHPPT	BBAABBbBB
L	kappa	Mus.musculus	Mo_IGKV4-72*01	94.2	Mo_IGKV4-72*01	83.3	L4	6	L4-6-1	15	GSGTSF	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022