PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 5GS0

#CDRs = 8; #Clusters = 16.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
C	lambda	Mus.musculus	Hu_IGLV3-21*02	90.9	Hu_IGLV3-21*02	63.6	L1	11	L1-11-3	12	SGDNIGSYYVH	BEBLAAABBBB
C	lambda	Mus.musculus	Hu_IGLV3-21*02	90.9	Hu_IGLV3-21*02	75.0	L2	8	L2-8-1	23	YEDSERPS	BLLABBBB
C	lambda	Mus.musculus	Hu_IGLV3-21*02	90.9	Hu_IGLV3-21*02	11.1	L3	10	L3-10-*	-1	SSYDDPNFQV	BBBBAABABB
C	lambda	Mus.musculus	Hu_IGLV3-21*02	90.9	Hu_IGLV3-21*02	100.0	L4	6	L4-6-2	15	NSGNTA	BBEABB
D	heavy	Mus.musculus	Hu_IGHV6-1*01	94.5	Hu_IGHV6-1*01	93.3	H1	15	H1-15-*	-1	AISGDSVSSnsAAWG	BBBLBBAABBLBBBB
D	heavy	Mus.musculus	Hu_IGHV6-1*01	94.5	Hu_IGHV6-1*01	54.5	H2	11	H2-11-*	-1	IIQKRSKwYNN	BBBBAABBBBB
D	heavy	Mus.musculus	Hu_IGHV6-1*01	94.5	Hu_IGHV6-1*01	100.0	H3	12	H3-12-*	-1	ARYSYPFYSIDY	BBBBBaALBBAB
D	heavy	Mus.musculus	Hu_IGHV6-1*01	94.5	Hu_IGHV6-1*01	100.0	H4	8	H4-8-1	16	PDTSKNQF	BBAAALBB
E	lambda	Mus.musculus	Hu_IGLV3-21*02	90.9	Hu_IGLV3-21*02	63.6	L1	11	L1-11-3	12	SGDNIGSYYVH	BEBLAAABBBB
E	lambda	Mus.musculus	Hu_IGLV3-21*02	90.9	Hu_IGLV3-21*02	75.0	L2	8	L2-8-1	24	YEDSERPS	BLLABBBB
E	lambda	Mus.musculus	Hu_IGLV3-21*02	90.9	Hu_IGLV3-21*02	11.1	L3	10	L3-10-*	-1	SSYDDPNFQV	BBBBAABABB
E	lambda	Mus.musculus	Hu_IGLV3-21*02	90.9	Hu_IGLV3-21*02	100.0	L4	6	L4-6-2	15	NSGNTA	BBEABB
F	heavy	Mus.musculus	Hu_IGHV6-1*01	94.5	Hu_IGHV6-1*01	93.3	H1	15	H1-15-*	-1	AISGDSVSSnsAAWG	BBBLBBAABBLBBBB
F	heavy	Mus.musculus	Hu_IGHV6-1*01	94.5	Hu_IGHV6-1*01	54.5	H2	11	H2-11-*	-1	IIQKRSKwYNN	BBBBAABBBBB
F	heavy	Mus.musculus	Hu_IGHV6-1*01	94.5	Hu_IGHV6-1*01	100.0	H3	12	H3-12-*	-1	ARYSYPFYSIDY	BBBBBaALBBAB
F	heavy	Mus.musculus	Hu_IGHV6-1*01	94.5	Hu_IGHV6-1*01	100.0	H4	8	H4-8-1	16	PDTSKNQF	BBAAALBB
H	heavy	Mus.musculus	Mo_IGHV3-6*01	94.4	Mo_IGHV3-6*01	100.0	H1	14	H1-14-1	18	SVTGYSITSgYYWN	BBBLBBAAABEBBB
H	heavy	Mus.musculus	Mo_IGHV3-6*01	94.4	Mo_IGHV3-6*01	100.0	H2	9	H2-9-1	16	YISYDGSNN	BBBAALBBB
H	heavy	Mus.musculus	Mo_IGHV3-6*01	94.4	Mo_IGHV3-6*01	100.0	H3	9	H3-9-2	19	ARAYIGFAY	BBBAABBAB
H	heavy	Mus.musculus	Mo_IGHV3-6*01	94.4	Mo_IGHV3-6*01	100.0	H4	8	H4-8-1	12	RDTSKNQF	BBAAALBB
L	kappa	Mus.musculus	Mo_IGKV10-96*01	95.7	Mo_IGKV10-96*01	81.8	L1	11	L1-11-*	-1	RAGQDISNHLN	BBAABALLABB
L	kappa	Mus.musculus	Mo_IGKV10-96*01	95.7	Mo_IGKV10-96*01	100.0	L2	8	L2-8-*	-1	YYTSRLHS	BLEBBBBB
L	kappa	Mus.musculus	Mo_IGKV10-96*01	95.7	Mo_IGKV10-96*01	100.0	L3	9	L3-9-cis7-1	15	QQGNTLPWT	BBAABBbBB
L	kappa	Mus.musculus	Mo_IGKV10-96*01	95.7	Mo_IGKV10-96*01	100.0	L4	6	L4-6-1	19	GSGTDY	EBEABB
X	heavy	Mus.musculus	Mo_IGHV3-6*01	94.4	Mo_IGHV3-6*01	100.0	H1	14	H1-14-1	18	SVTGYSITSgYYWN	BBBLBBAAABEBBB
X	heavy	Mus.musculus	Mo_IGHV3-6*01	94.4	Mo_IGHV3-6*01	100.0	H2	9	H2-9-1	16	YISYDGSNN	BBBAALBBB
X	heavy	Mus.musculus	Mo_IGHV3-6*01	94.4	Mo_IGHV3-6*01	100.0	H3	9	H3-9-2	18	ARAYIGFAY	BBBAABBAB
X	heavy	Mus.musculus	Mo_IGHV3-6*01	94.4	Mo_IGHV3-6*01	100.0	H4	8	H4-8-1	12	RDTSKNQF	BBAAALBB
Y	kappa	Mus.musculus	Mo_IGKV10-96*01	95.7	Mo_IGKV10-96*01	81.8	L1	11	L1-11-2	19	RAGQDISNHLN	BBABBALLABB
Y	kappa	Mus.musculus	Mo_IGKV10-96*01	95.7	Mo_IGKV10-96*01	100.0	L2	8	L2-8-*	-1	YYTSRLHS	BLEABBBB
Y	kappa	Mus.musculus	Mo_IGKV10-96*01	95.7	Mo_IGKV10-96*01	100.0	L3	9	L3-9-cis7-1	15	QQGNTLPWT	BBAABBbBB
Y	kappa	Mus.musculus	Mo_IGKV10-96*01	95.7	Mo_IGKV10-96*01	100.0	L4	6	L4-6-1	25	GSGTDY	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022