PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 5FHC

#CDRs = 8; #Clusters = 13.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	heavy	Homo.sapiens	Hu_IGHV4-59*07	90.4	Hu_IGHV4-59*07	84.6	H1	13	H1-13-*	-1	TVSGGSLSSFYWS	BBBBEBAAABBBB
A	heavy	Homo.sapiens	Hu_IGHV4-59*07	90.4	Hu_IGHV4-59*07	88.9	H2	9	H2-9-*	-1	YIYYSGSPN	BBBAABBBB
A	heavy	Homo.sapiens	Hu_IGHV4-59*07	90.4	Hu_IGHV4-59*07	50.0	H3	19	H3-19-*	-1	VRASRSYYWgsyrpTAFDS
A	heavy	Homo.sapiens	Hu_IGHV4-59*07	90.4	Hu_IGHV4-59*07	62.5	H4	8	H4-8-1	9	VDTTRNQI	BBAAALBB
B	lambda	Homo.sapiens	Hu_IGLV3-1*01	86.4	Hu_IGLV3-1*01	81.8	L1	11	L1-11-3	6	SGDNLGDKYVC	BBBLAAABBBB
B	lambda	Homo.sapiens	Hu_IGLV3-1*01	86.4	Hu_IGLV3-1*01	87.5	L2	8	L2-8-1	10	YQDNKRPS	BLLABBBB
B	lambda	Homo.sapiens	Hu_IGLV3-1*01	86.4	Hu_IGLV3-1*01	50.0	L3	8	L3-8-4	12	QTWDSTVV	BBBBABBB
B	lambda	Homo.sapiens	Hu_IGLV3-1*01	86.4	Hu_IGLV3-1*01	100.0	L4	6	L4-6-2	15	NSGNTA	BBEABB
H	heavy	Homo.sapiens	Hu_IGHV3-13*01	83.6	Hu_IGHV3-13*01	69.2	H1	13	H1-13-*	-1	AASGFALRMYDMH	BBBLBBAAABBBB
H	heavy	Homo.sapiens	Hu_IGHV3-13*01	83.6	Hu_IGHV3-13*01	66.7	H2	9	H2-9-1	8	AVGPSGDTY	BBBAALBBB
H	heavy	Homo.sapiens	Hu_IGHV3-13*01	83.6	Hu_IGHV3-13*01	50.0	H3	13	H3-13-*	-1	VRSDRGVAGLFDS	BBBBBEBBLBBAB
H	heavy	Homo.sapiens	Hu_IGHV3-13*01	83.6	Hu_IGHV3-13*01	100.0	H4	8	H4-8-1	10	RENAKNSL	BBAAALBB
L	kappa	Homo.sapiens	Hu_IGKV1-27*01	95.7	Hu_IGKV1-27*01	63.6	L1	11	L1-11-*	-1	RASQAFDNYVA	BBABBALLBBB
L	kappa	Homo.sapiens	Hu_IGKV1-27*01	95.7	Hu_IGKV1-27*01	50.0	L2	8	L2-8-1	13	SAASALHA	BLLABBBB
L	kappa	Homo.sapiens	Hu_IGKV1-27*01	95.7	Hu_IGKV1-27*01	85.7	L3	9	L3-9-cis7-*	-1	QNYNSAPLT	BBBLBBbBB
L	kappa	Homo.sapiens	Hu_IGKV1-27*01	95.7	Hu_IGKV1-27*01	83.3	L4	6	L4-6-1	6	GSGTHF	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022