PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 5DSC

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	90.0	Rb_IGHV1S69*01	69.2	H1	13	H1-13-1	17	TVSGFDISDYAMI	BBBLBBAAABBBB
A	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	90.0	CDRLenMismatch	-1.0	H2	10	H2-10-*	-1	IIYGVINDLA	BBBAABBBBB
A	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	90.0	Rb_IGHV1S69*01	100.0	H3	15	H3-15-*	-1	ARGYGSmDGYDRLNL
A	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	90.0	Rb_IGHV1S69*01	83.3	H4	6	H4-6-1	9	RTSTTV	BBAABB
B	kappa	Oryctolagus.cuniculus	Rb_IGKV1S19*01	91.0	Rb_IGKV1S19*01	46.2	L1	13	L1-13-3	9	RSRQRVYlgDWLS	BBABBBBLLABBB
B	kappa	Oryctolagus.cuniculus	Rb_IGKV1S19*01	91.0	Rb_IGKV1S19*01	50.0	L2	8	L2-8-1	3	YDASFRGD	BLLABBBB
B	kappa	Oryctolagus.cuniculus	Rb_IGKV1S19*01	91.0	Rb_IGKV1S19*01	88.9	L3	11	L3-11-*	-1	LGgyYDDADDT	BBBBABAAABB
B	kappa	Oryctolagus.cuniculus	Rb_IGKV1S19*01	91.0	Rb_IGKV1S19*01	83.3	L4	6	L4-6-1	6	GSGTHF	EBEABB
C	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	90.0	Rb_IGHV1S69*01	69.2	H1	13	H1-13-1	17	TVSGFDISDYAMI	BBBLBBAAABBBB
C	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	90.0	CDRLenMismatch	-1.0	H2	10	H2-10-*	-1	IIYGVINDLA	BBBAABBBBB
C	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	90.0	Rb_IGHV1S69*01	100.0	H3	15	H3-15-*	-1	ARGYGSmDGYDRLNL
C	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	90.0	Rb_IGHV1S69*01	83.3	H4	6	H4-6-1	9	RTSTTV	BBAABB
D	kappa	Oryctolagus.cuniculus	Rb_IGKV1S19*01	91.0	Rb_IGKV1S19*01	46.2	L1	13	L1-13-3	10	RSRQRVYlgDWLS	BBABBBBLLABBB
D	kappa	Oryctolagus.cuniculus	Rb_IGKV1S19*01	91.0	Rb_IGKV1S19*01	50.0	L2	8	L2-8-1	3	YDASFRGD	BLLABBBB
D	kappa	Oryctolagus.cuniculus	Rb_IGKV1S19*01	91.0	Rb_IGKV1S19*01	88.9	L3	11	L3-11-*	-1	LGgyYDDADDT	BBBBABAAABB
D	kappa	Oryctolagus.cuniculus	Rb_IGKV1S19*01	91.0	Rb_IGKV1S19*01	83.3	L4	6	L4-6-1	6	GSGTHF	EBEABB
E	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	90.0	Rb_IGHV1S69*01	69.2	H1	13	H1-13-1	17	TVSGFDISDYAMI	BBBLBBAAABBBB
E	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	90.0	CDRLenMismatch	-1.0	H2	10	H2-10-*	-1	IIYGVINDLA	BBBAABBBBB
E	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	90.0	Rb_IGHV1S69*01	100.0	H3	15	H3-15-*	-1	ARGYGSmDGYDRLNL
E	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	90.0	Rb_IGHV1S69*01	83.3	H4	6	H4-6-1	8	RTSTTV	BBAABB
F	kappa	Oryctolagus.cuniculus	Rb_IGKV1S19*01	91.0	Rb_IGKV1S19*01	46.2	L1	13	L1-13-3	9	RSRQRVYlgDWLS	BBABBBBLLABBB
F	kappa	Oryctolagus.cuniculus	Rb_IGKV1S19*01	91.0	Rb_IGKV1S19*01	50.0	L2	8	L2-8-1	3	YDASFRGD	BLLABBBB
F	kappa	Oryctolagus.cuniculus	Rb_IGKV1S19*01	91.0	Rb_IGKV1S19*01	88.9	L3	11	L3-11-*	-1	LGgyYDDADDT	BBBBABAAABB
F	kappa	Oryctolagus.cuniculus	Rb_IGKV1S19*01	91.0	Rb_IGKV1S19*01	83.3	L4	6	L4-6-1	6	GSGTHF	EBEABB
H	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	90.0	Rb_IGHV1S69*01	69.2	H1	13	H1-13-1	17	TVSGFDISDYAMI	BBBLBBAAABBBB
H	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	90.0	CDRLenMismatch	-1.0	H2	10	H2-10-*	-1	IIYGVINDLA	BBBAABBBBB
H	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	90.0	Rb_IGHV1S69*01	100.0	H3	15	H3-15-*	-1	ARGYGSmDGYDRLNL
H	heavy	Oryctolagus.cuniculus	Rb_IGHV1S69*01	90.0	Rb_IGHV1S69*01	83.3	H4	6	H4-6-1	9	RTSTTV	BBAABB
L	kappa	Oryctolagus.cuniculus	Rb_IGKV1S19*01	91.0	Rb_IGKV1S19*01	46.2	L1	13	L1-13-3	9	RSRQRVYlgDWLS	BBABBBBLLABBB
L	kappa	Oryctolagus.cuniculus	Rb_IGKV1S19*01	91.0	Rb_IGKV1S19*01	50.0	L2	8	L2-8-1	3	YDASFRGD	BLLABBBB
L	kappa	Oryctolagus.cuniculus	Rb_IGKV1S19*01	91.0	Rb_IGKV1S19*01	88.9	L3	11	L3-11-*	-1	LGgyYDDADDT	BBBBABAAABB
L	kappa	Oryctolagus.cuniculus	Rb_IGKV1S19*01	91.0	Rb_IGKV1S19*01	83.3	L4	6	L4-6-1	6	GSGTHF	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022