PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 2GHW

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
B	heavy	Homo.sapiens	Hu_IGHV3-33*03	95.9	Ra_IGHV5-50*01	76.9	H1	13	H1-13-1	10	AASGFAFSSYAMH	BBBLBBAAABBBB
B	heavy	Homo.sapiens	Hu_IGHV3-33*03	95.9	Ra_IGHV5-50*01	70.0	H2	10	H2-10-2	8	VISYDGSNKY	BBBAALABBB
B	heavy	Homo.sapiens	Hu_IGHV3-33*03	95.9	Hu_IGHV3-33*03	50.0	H3	10	H3-10-1	15	ARDRSYYLDY	BBBBLLBBAB
B	heavy	Homo.sapiens	Hu_IGHV3-33*03	95.9	Hu_IGHV3-33*03	100.0	H4	8	H4-8-1	7	RDNSKNTL	BBAAALBB
B	kappa	Homo.sapiens	Hu_IGKV3D-20*02	97.0	Ra_IGKV18S1*01	72.7	L1	11	L1-11-1	10	RASQSVRSNLA	BBABBAEABBB
B	kappa	Homo.sapiens	Hu_IGKV3D-20*02	97.0	Ra_IGKV18S1*01	62.5	L2	8	L2-8-1	7	YDASTRAT	BLLABBBB
B	kappa	Homo.sapiens	Hu_IGKV3D-20*02	97.0	Hu_IGKV3D-20*02	85.7	L3	9	L3-9-cis7-1	16	QQRSNWPPT	BBAABBbBB
B	kappa	Homo.sapiens	Hu_IGKV3D-20*02	97.0	Hu_IGKV3D-20*02	100.0	L4	6	L4-6-1	16	GSGTDF	EBEABB
D	heavy	Homo.sapiens	Hu_IGHV3-33*03	95.9	Ra_IGHV5-50*01	76.9	H1	13	H1-13-1	8	AASGFAFSSYAMH	BBBLBBAAABBBB
D	heavy	Homo.sapiens	Hu_IGHV3-33*03	95.9	Ra_IGHV5-50*01	70.0	H2	10	H2-10-2	10	VISYDGSNKY	BBBAALABBB
D	heavy	Homo.sapiens	Hu_IGHV3-33*03	95.9	Hu_IGHV3-33*03	50.0	H3	10	H3-10-1	15	ARDRSYYLDY	BBBBLLBBAB
D	heavy	Homo.sapiens	Hu_IGHV3-33*03	95.9	Hu_IGHV3-33*03	100.0	H4	8	H4-8-1	4	RDNSKNTL	BBAAALBB
D	kappa	Homo.sapiens	Hu_IGKV3D-20*02	97.0	Ra_IGKV18S1*01	72.7	L1	11	L1-11-1	10	RASQSVRSNLA	BBABBAEAABB
D	kappa	Homo.sapiens	Hu_IGKV3D-20*02	97.0	Ra_IGKV18S1*01	62.5	L2	8	L2-8-1	8	YDASTRAT	BLLABBBB
D	kappa	Homo.sapiens	Hu_IGKV3D-20*02	97.0	Hu_IGKV3D-20*02	85.7	L3	9	L3-9-cis7-1	17	QQRSNWPPT	BBAABBbBB
D	kappa	Homo.sapiens	Hu_IGKV3D-20*02	97.0	Hu_IGKV3D-20*02	100.0	L4	6	L4-6-1	16	GSGTDF	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022