PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 1PG7

#CDRs = 8; #Clusters = 12.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
H	heavy	Mus.musculus.Homo.sapiens	Hu_IGHV3-66*01	86.3	Mo_IGHV14-1*02	84.6	H1	13	H1-13-1	12	AASGFNIKEYYMH	BBBLBBAAABBBB
H	heavy	Mus.musculus.Homo.sapiens	Hu_IGHV3-66*01	86.3	Mo_IGHV14-1*02	80.0	H2	10	H2-10-1	14	LIDPEQGNTI	BBBAAALBBB
H	heavy	Mus.musculus.Homo.sapiens	Hu_IGHV3-66*01	86.3	Hu_IGHV3-66*01	100.0	H3	10	H3-10-1	10	ARDTAAYFDY	BBBBLLBBAB
H	heavy	Mus.musculus.Homo.sapiens	Hu_IGHV3-66*01	86.3	Hu_IGHV3-66*01	75.0	H4	8	H4-8-1	6	ADNSKNTA	BBAAALBB
I	heavy	Mus.musculus.Homo.sapiens	Hu_IGHV3-66*01	86.3	Mo_IGHV14-1*02	84.6	H1	13	H1-13-1	11	AASGFNIKEYYMH	BBBLBBAAABBBB
I	heavy	Mus.musculus.Homo.sapiens	Hu_IGHV3-66*01	86.3	Mo_IGHV14-1*02	80.0	H2	10	H2-10-1	15	LIDPEQGNTI	BBBAAALBBB
I	heavy	Mus.musculus.Homo.sapiens	Hu_IGHV3-66*01	86.3	Hu_IGHV3-66*01	100.0	H3	10	H3-10-1	10	ARDTAAYFDY	BBBBLLBBAB
I	heavy	Mus.musculus.Homo.sapiens	Hu_IGHV3-66*01	86.3	Hu_IGHV3-66*01	75.0	H4	8	H4-8-1	8	ADNSKNTA	BBAAALBB
L	kappa	Mus.musculus.Homo.sapiens	Hu_IGKV1-NL1*01	97.1	Mo_IGKV14-126*01	72.7	L1	11	L1-11-2	6	RASRDIKSYLN	BBABBALLBBB
L	kappa	Mus.musculus.Homo.sapiens	Hu_IGKV1-NL1*01	97.1	Mo_IGKV14-126*01	87.5	L2	8	L2-8-1	4	YYATSLAE	BLLABBBB
L	kappa	Mus.musculus.Homo.sapiens	Hu_IGKV1-NL1*01	97.1	Hu_IGKV1-NL1*01	28.6	L3	9	L3-9-cis7-1	11	LQHGESPWT	BBAABBbBB
L	kappa	Mus.musculus.Homo.sapiens	Hu_IGKV1-NL1*01	97.1	Hu_IGKV1-NL1*01	100.0	L4	6	L4-6-1	6	GSGTDY	EBEABB
M	kappa	Mus.musculus.Homo.sapiens	Hu_IGKV1-NL1*01	97.1	Mo_IGKV14-126*01	72.7	L1	11	L1-11-2	6	RASRDIKSYLN	BBABBALLBBB
M	kappa	Mus.musculus.Homo.sapiens	Hu_IGKV1-NL1*01	97.1	Mo_IGKV14-126*01	87.5	L2	8	L2-8-1	4	YYATSLAE	BLLABBBB
M	kappa	Mus.musculus.Homo.sapiens	Hu_IGKV1-NL1*01	97.1	Hu_IGKV1-NL1*01	28.6	L3	9	L3-9-cis7-1	10	LQHGESPWT	BBAABBbBB
M	kappa	Mus.musculus.Homo.sapiens	Hu_IGKV1-NL1*01	97.1	Hu_IGKV1-NL1*01	100.0	L4	6	L4-6-1	5	GSGTDY	EBEABB
W	lambda	Mus.musculus	Mo_IGLV1*01	97.1	Mo_IGLV1*01	100.0	L1	14	L1-14-1	8	RSSTGAVTtSNYAN	BBAAEBBBAAALBB
W	lambda	Mus.musculus	Mo_IGLV1*01	97.1	Mo_IGLV1*01	100.0	L2	8	L2-8-1	9	GGTNNRAP	BLEABBBB
W	lambda	Mus.musculus	Mo_IGLV1*01	97.1	Mo_IGLV1*01	87.5	L3	9	L3-9-4	6	ALWYSNHWV	BBBBEABBB
W	lambda	Mus.musculus	Mo_IGLV1*01	97.1	Mo_IGLV1*01	100.0	L4	6	L4-6-2	16	LIGDKA	BBEABB
X	heavy	Mus.musculus	Mo_IGHV1-37*01	86.3	Mo_IGHV1-37*01	76.9	H1	13	H1-13-1	12	KASGYSFTGHLLN	BBBLBBAAABBBB
X	heavy	Mus.musculus	Mo_IGHV1-37*01	86.3	Mo_IGHV1-37*01	30.0	H2	10	H2-10-1	13	LVHPHNGAIT	BBBAAALBBB
X	heavy	Mus.musculus	Mo_IGHV1-37*01	86.3	Mo_IGHV1-37*01	100.0	H3	13	H3-13-*	-1	AREDFRYHYSMDY	BBBBAAABABBAB
X	heavy	Mus.musculus	Mo_IGHV1-37*01	86.3	Mo_IGHV1-37*01	75.0	H4	8	H4-8-1	7	VDRSSTTA	BBAAALBB
Y	lambda	Mus.musculus	Mo_IGLV1*01	97.1	Mo_IGLV1*01	100.0	L1	14	L1-14-1	8	RSSTGAVTtSNYAN	BBAAEBBBAAALBB
Y	lambda	Mus.musculus	Mo_IGLV1*01	97.1	Mo_IGLV1*01	100.0	L2	8	L2-8-1	10	GGTNNRAP	BLLABBBB
Y	lambda	Mus.musculus	Mo_IGLV1*01	97.1	Mo_IGLV1*01	87.5	L3	9	L3-9-4	5	ALWYSNHWV	BBBBEABBB
Y	lambda	Mus.musculus	Mo_IGLV1*01	97.1	Mo_IGLV1*01	100.0	L4	6	L4-6-2	18	LIGDKA	BBEABB
Z	heavy	Mus.musculus	Mo_IGHV1-37*01	86.3	Mo_IGHV1-37*01	76.9	H1	13	H1-13-1	10	KASGYSFTGHLLN	BBBLBBAAABBBB
Z	heavy	Mus.musculus	Mo_IGHV1-37*01	86.3	Mo_IGHV1-37*01	30.0	H2	10	H2-10-1	11	LVHPHNGAIT	BBBAAALBBB
Z	heavy	Mus.musculus	Mo_IGHV1-37*01	86.3	Mo_IGHV1-37*01	100.0	H3	13	H3-13-*	-1	AREDFRYHYSMDY	BBBBAAABABBAB
Z	heavy	Mus.musculus	Mo_IGHV1-37*01	86.3	Mo_IGHV1-37*01	75.0	H4	8	H4-8-1	8	VDRSSTTA	BBAAALBB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022