PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 5FGB

#CDRs = 8; #Clusters = 9.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	lambda	Homo.sapiens	Hu_IGLV3-1*01	89.6	Hu_IGLV3-1*01	72.7	L1	11	L1-11-4	16	SGDNLGDKFVC	BBAAAAABBBB
A	lambda	Homo.sapiens	Hu_IGLV3-1*01	89.6	Hu_IGLV3-1*01	75.0	L2	8	L2-8-1	5	YEDTKRPS	BLEABBBB
A	lambda	Homo.sapiens	Hu_IGLV3-1*01	89.6	Hu_IGLV3-1*01	75.0	L3	10	L3-10-3	16	QTWDSSTDVV	BBBBAAAEBB
A	lambda	Homo.sapiens	Hu_IGLV3-1*01	89.6	Hu_IGLV3-1*01	100.0	L4	6	L4-6-2	14	NSGNTA	BBEABB
B	lambda	Homo.sapiens	Hu_IGLV3-1*01	89.6	Hu_IGLV3-1*01	72.7	L1	11	L1-11-3	7	SGDNLGDKFVC	BBBLAAABBBB
B	lambda	Homo.sapiens	Hu_IGLV3-1*01	89.6	Hu_IGLV3-1*01	75.0	L2	8	L2-8-1	5	YEDTKRPS	BLEABBBB
B	lambda	Homo.sapiens	Hu_IGLV3-1*01	89.6	Hu_IGLV3-1*01	75.0	L3	10	L3-10-3	15	QTWDSSTDVV	BBBBAAAEBB
B	lambda	Homo.sapiens	Hu_IGLV3-1*01	89.6	Hu_IGLV3-1*01	100.0	L4	6	L4-6-2	13	NSGNTA	BBEABB
C	heavy	Homo.sapiens	Hu_IGHV3-23*04	94.5	Hu_IGHV3-23*04	100.0	H1	13	H1-13-1	9	AASGFTFSSYAMS	BBBLBBAAABBBB
C	heavy	Homo.sapiens	Hu_IGHV3-23*04	94.5	Hu_IGHV3-23*04	100.0	H2	10	H2-10-2	8	AISGSGGSTY	BBBAALABBB
C	heavy	Homo.sapiens	Hu_IGHV3-23*04	94.5	Hu_IGHV3-23*04	50.0	H3	20	H3-20-*	-1	ARavvftdssayYYSKYFDY
C	heavy	Homo.sapiens	Hu_IGHV3-23*04	94.5	Hu_IGHV3-23*04	87.5	H4	8	H4-8-1	5	RDNSKNIL	BBAAALBB
E	heavy	Homo.sapiens	Hu_IGHV3-23*04	94.5	Hu_IGHV3-23*04	100.0	H1	13	H1-13-1	9	AASGFTFSSYAMS	BBBLBBAAABBBB
E	heavy	Homo.sapiens	Hu_IGHV3-23*04	94.5	Hu_IGHV3-23*04	100.0	H2	10	H2-10-2	9	AISGSGGSTY	BBBAALABBB
E	heavy	Homo.sapiens	Hu_IGHV3-23*04	94.5	Hu_IGHV3-23*04	50.0	H3	20	H3-20-*	-1	ARavvftdssayyySKYFDY
E	heavy	Homo.sapiens	Hu_IGHV3-23*04	94.5	Hu_IGHV3-23*04	87.5	H4	8	H4-8-1	6	RDNSKNIL	BBAAALBB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022