PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDR Structures for L3-10-3

Summary info for L3-10-3
Loop	# of Structures	% of Loop Length	Median PDB	Consensus Sequence	# of Unique Seq	% of Unique Seq	Gene	Loop Conformation	Median Angle	Consensus Sequence Logo
L3-10-3	42	3.70	2L_5FGBB	QVWDSSSDvV	19	5.54	kappa lambda	BBBBAAAEBB	15

Structures in cluster L3-10-3
Cluster	PDB	Resolution	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	Sequence	Ramachandran	Distance(°)
L3-10-3	6Y1NL	2.2	lambda	Homo.sapiens	Hu_IGLV1-47*01	100.0	Hu_IGLV1-47*01	77.8	AAWDDSLGTV	BBBBAAAEBB	18
L3-10-3	7VYRB	2.2	lambda	Homo.sapiens	Hu_IGLV3-21*03	98.5	Hu_IGLV3-21*03	55.6	QVYDLFSDYV	BBBBAAAEBB	10
L3-10-3	7VYRL	2.2	lambda	Homo.sapiens	Hu_IGLV3-21*03	98.5	Hu_IGLV3-21*03	55.6	QVYDLFSDYV	BBBBAAAEBB	12
L3-10-3	4UU9B	2.12	lambda	Homo.sapiens	Hu_IGLV2-14*01	95.6	Hu_IGLV2-14*01	33.3	TSYHPTKTIL	BBBBAAAEBB	16
L3-10-3	4UU9L	2.12	lambda	Homo.sapiens	Hu_IGLV2-14*01	95.6	Hu_IGLV2-14*01	33.3	TSYHPTKTIL	BBBBAAAEBB	16
L3-10-3	7SEMC	2.2	lambda	Homo.sapiens	Hu_IGLV1-40*02	98.5	Hu_IGLV1-40*02	88.9	QSYDRSLSGV	BBBBAAAEBB	17
L3-10-3	8CW9M	EM	lambda	Homo.sapiens	Hu_IGLV1-40*02	98.5	Hu_IGLV1-40*02	88.9	QSYDRSLSGV	BBBBAAAEBB	24
L3-10-3	8CW9B	EM	lambda	Homo.sapiens	Hu_IGLV1-40*02	98.5	Hu_IGLV1-40*02	88.9	QSYDRSLSGV	BBBBAAAEBB	16
L3-10-3	8CW9O	EM	lambda	Homo.sapiens	Hu_IGLV1-40*02	98.5	Hu_IGLV1-40*02	88.9	QSYDRSLSGV	BBBBAAAEBB	25
L3-10-3	4OSUL	1.87	lambda	Homo.sapiens	Hu_IGLV1-51*01	94.1	Hu_IGLV1-51*01	66.7	GTPDRSLSVI	BBBBAAAEBB	19
L3-10-3	4OT1L	2.11	lambda	Homo.sapiens	Hu_IGLV1-51*01	94.1	Hu_IGLV1-51*01	66.7	GTPDRSLSVV	BBBBAAAEBB	18
L3-10-3	6KTRB	2.598	lambda	Homo.sapiens	Hu_IGLV2-14*01	94.0	Hu_IGLV2-14*01	66.7	SSWTRSSGLV	BBBBAAAEBB	18
L3-10-3	6KTRG	2.598	lambda	Homo.sapiens	Hu_IGLV2-14*01	94.0	Hu_IGLV2-14*01	66.7	SSWTRSSGLV	BBBBAAAEBB	20
L3-10-3	2DD8L	2.3	lambda	Homo.sapiens	Hu_IGLV3-21*03	98.5	Hu_IGLV3-21*03	88.9	QVWDSSSDYV	BBBBAAAEBB	11
L3-10-3	2G75B	2.28	lambda	Homo.sapiens	Hu_IGLV3-21*03	98.5	Hu_IGLV3-21*03	88.9	QVWDSSSDYV	BBBBAAAEBB	12
L3-10-3	2G75D	2.28	lambda	Homo.sapiens	Hu_IGLV3-21*03	98.5	Hu_IGLV3-21*03	88.9	QVWDSSSDYV	BBBBAAAEBB	12
L3-10-3	3G6AL	2.1	lambda	Homo.sapiens	Hu_IGLV3-9*01	91.0	Hu_IGLV3-9*01	37.5	GTWDMVTNNV	BBBBAAAEBB	13
L3-10-3	3G6DL	3.2	lambda	Homo.sapiens	Hu_IGLV3-9*01	91.0	Hu_IGLV3-9*01	37.5	GTWDMVTNNV	BBBBAAAEBB	15
L3-10-3	3G6AA	2.1	lambda	Homo.sapiens	Hu_IGLV3-9*01	91.0	Hu_IGLV3-9*01	37.5	GTWDMVTNNV	BBBBAAAEBB	13
L3-10-3	3UJIL	1.6	lambda	Homo.sapiens	Hu_IGLV3-1*01	94.0	Hu_IGLV3-1*01	62.5	QAWDSTLGVV	BBBBAAAEBB	18
L3-10-3	3ULSA	2.495	lambda	Homo.sapiens	Hu_IGLV3-21*02	90.9	Hu_IGLV3-21*02	11.1	SSYDDPNFQV	BBBBAAAEBB	18
L3-10-3	4QHMF	3.23	lambda	Homo.sapiens	Hu_IGLV3-1*01	85.1	Hu_IGLV3-1*01	50.0	QVWDSFSTFV	BBBBAAAEBB	19
L3-10-3	4QHNB	3	lambda	Homo.sapiens	Hu_IGLV3-1*01	85.1	Hu_IGLV3-1*01	50.0	QVWDSFSTFV	BBBBAAAEBB	13
L3-10-3	4QHMD	3.23	lambda	Homo.sapiens	Hu_IGLV3-1*01	85.1	Hu_IGLV3-1*01	50.0	QVWDSFSTFV	BBBBAAAEBB	20
L3-10-3	4QHMB	3.23	lambda	Homo.sapiens	Hu_IGLV3-1*01	85.1	Hu_IGLV3-1*01	50.0	QVWDSFSTFV	BBBBAAALBB	22
L3-10-3	4QHMH	3.23	lambda	Homo.sapiens	Hu_IGLV3-1*01	85.1	Hu_IGLV3-1*01	50.0	QVWDSFSTFV	BBBBAAAEBB	20
L3-10-3	5FGBA	1.65	lambda	Homo.sapiens	Hu_IGLV3-1*01	89.6	Hu_IGLV3-1*01	75.0	QTWDSSTDVV	BBBBAAAEBB	16
L3-10-3	5FGCB	1.9	lambda	Homo.sapiens	Hu_IGLV3-1*01	88.1	Hu_IGLV3-1*01	87.5	QAWDSSTDVV	BBBBAAAEBB	17
L3-10-3	5FGBB	1.65	lambda	Homo.sapiens	Hu_IGLV3-1*01	89.6	Hu_IGLV3-1*01	75.0	QTWDSSTDVV	BBBBAAAEBB	15
L3-10-3	6FY1L	3.132	lambda	Homo.sapiens	Hu_IGLV3-21*03	89.6	Hu_IGLV3-21*03	55.6	QVWHSTSAVI	BBBBAAAEBB	18
L3-10-3	6FY1Z	3.132	lambda	Homo.sapiens	Hu_IGLV3-21*03	89.6	Hu_IGLV3-21*03	55.6	QVWHSTSAVI	BBBBAAAEBB	14
L3-10-3	6VPYB	2.36	lambda	Homo.sapiens	Hu_IGLV3-1*01	97.0	Hu_IGLV3-1*01	62.5	QAWDSFSTFV	BBBBAAAEBB	14
L3-10-3	6VPYL	2.36	lambda	Homo.sapiens	Hu_IGLV3-1*01	97.0	Hu_IGLV3-1*01	62.5	QAWDSFSTFV	BBBBAAAEBB	14
L3-10-3	7KZCD	2.3	lambda	Homo.sapiens	Hu_IGLV3-21*03	98.5	Hu_IGLV3-21*03	66.7	QVWDTYSDYV	BBBBAAAEBB	13
L3-10-3	7KZCL	2.3	lambda	Homo.sapiens	Hu_IGLV3-21*03	98.5	Hu_IGLV3-21*03	66.7	QVWDTYSDYV	BBBBAAAEBB	14
L3-10-3	4JAMB	1.65	lambda	Homo.sapiens	Hu_IGLV3-1*01	86.4	Hu_IGLV3-1*01	50.0	QVWDSFSTFV	BBBBAAAEBB	15
L3-10-3	4JANB	3.15	lambda	Homo.sapiens	Hu_IGLV3-1*01	86.4	Hu_IGLV3-1*01	50.0	QVWDSFSTFV	BBBBAAAEBB	15
L3-10-3	4JAML	1.65	lambda	Homo.sapiens	Hu_IGLV3-1*01	86.4	Hu_IGLV3-1*01	50.0	QVWDSFSTFV	BBBBAAAEBB	16
L3-10-3	4JANL	3.15	lambda	Homo.sapiens	Hu_IGLV3-1*01	86.4	Hu_IGLV3-1*01	50.0	QVWDSFSTFV	BBBBAAAEBB	20
L3-10-3	7AHUL	2.6	kappa	Homo.sapiens	Hu_IGKV3-20*01	100.0	Hu_IGKV3-20*01	57.1	QQFGdSQLFT	BBBBAAAEBB	18
L3-10-3	7AHUA	2.6	kappa	Homo.sapiens	Hu_IGKV3-20*01	100.0	Hu_IGKV3-20*01	57.1	QQFGdSQLFT	BBBBAAAEBB	18
L3-10-3	4K94L	2.4	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	28.6	QQWAvHSLIT	BBBBAAAEBB	11

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022