PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDR Structures for L2-12-2

Summary info for L2-12-2
Loop	# of Structures	% of Loop Length	Median PDB	Consensus Sequence	# of Unique Seq	% of Unique Seq	Gene	Loop Conformation	Median Angle	Consensus Sequence Logo
L2-12-2	45	59.21	1L_5EORL	KlNSDGShTKGD	11	50.00	lambda	BBBAALBBBBBB	7

Structures in cluster L2-12-2
Cluster	PDB	Resolution	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	Sequence	Ramachandran	Distance(°)
L2-12-2	2OTUC	1.68	lambda	Mus.musculus	Hu_IGLV4-69*01	77.9	Hu_IGLV4-69*01	66.7	ELKKdgshSTGD	BBBAALBBBBBB	6
L2-12-2	2OTWA	2.35	lambda	Mus.musculus	Hu_IGLV4-69*01	77.9	Hu_IGLV4-69*01	66.7	ELKKdgshSTGD	BBBAALBBBBBB	7
L2-12-2	2OTUA	1.68	lambda	Mus.musculus	Hu_IGLV4-69*01	77.9	Hu_IGLV4-69*01	66.7	ELKKdgshSTGD	BBBAALBBBBBB	8
L2-12-2	2OTWC	2.35	lambda	Mus.musculus	Hu_IGLV4-69*01	77.9	Hu_IGLV4-69*01	66.7	ELKKdgshSTGD	BBBAALBBBBBB	9
L2-12-2	2OTUE	1.68	lambda	Mus.musculus	Hu_IGLV4-69*01	77.9	Hu_IGLV4-69*01	66.7	ELKKdgshSTGD	BBBAALBBBBBB	5
L2-12-2	2OTUG	1.68	lambda	Mus.musculus	Hu_IGLV4-69*01	77.9	Hu_IGLV4-69*01	66.7	ELKKdgshSTGD	BBBAALBBBBBB	5
L2-12-2	5EORL	2.27	lambda	Mus.musculus	Hu_IGLV4-69*01	77.9	Hu_IGLV4-69*01	58.3	ElrrdGSHNTGD	BBBAALBBBBBB	5
L2-12-2	5KG9B	2.3	lambda	Mus.musculus.Homo.sapiens	Hu_IGLV4-69*01	76.5	Hu_IGLV4-69*01	58.3	ElrkdGSHNTGD	BBBAALBBBBBB	9
L2-12-2	5KG9L	2.3	lambda	Mus.musculus.Homo.sapiens	Hu_IGLV4-69*01	76.5	Hu_IGLV4-69*01	58.3	ElrkdGSHNTGD	BBBAALBBBBBB	11
L2-12-2	6A4KN	3.15	lambda	Homo.sapiens	Hu_IGLV4-69*01	89.7	Hu_IGLV4-69*01	50.0	NlssgGRHTRGD	BBBAALBBBBBB	10
L2-12-2	6JP7L	1.909	lambda	Homo.sapiens	Hu_IGLV4-69*01	89.7	Hu_IGLV4-69*01	50.0	NlssgGRHTRGD	BBBAALBBBBBB	12
L2-12-2	7RYUL	1.51	lambda	Macaca.mulatta	Ma_IGLV4S4*01	86.8	Ma_IGLV4S4*01	75.0	RldsvGSHTKVD	BBBAALBBBBBB	13
L2-12-2	6A4KL	3.15	lambda	Homo.sapiens	Hu_IGLV4-69*01	89.7	Hu_IGLV4-69*01	50.0	NlssgGRHTRGD	BBBAALBBBBBB	14
L2-12-2	7TFNQ	EM	lambda	Macaca.mulatta	Ma_IGLV4S4*01	86.8	Ma_IGLV4S4*01	75.0	RldsvGSHTKVD	BBBAALBBBBBB	15
L2-12-2	6A4KO	3.15	lambda	Homo.sapiens	Hu_IGLV4-69*01	89.7	Hu_IGLV4-69*01	50.0	NlssgGRHTRGD	BBBAALBBBBBB	11
L2-12-2	5IHZF	1.64	lambda	Homo.sapiens	Hu_IGLV4-69*01	97.1	Hu_IGLV4-69*01	91.7	KVNsdgsHSKGD	BBBAALBBBBBB	12
L2-12-2	7RKSL	2.7	lambda	Homo.sapiens	Hu_IGLV4-69*01	98.5	Hu_IGLV4-69*01	91.7	KLNtdgsHSKGD	BBBAALBBBBBB	7
L2-12-2	5IHZD	1.64	lambda	Homo.sapiens	Hu_IGLV4-69*01	97.1	Hu_IGLV4-69*01	91.7	KVNsdgsHSKGD	BBBAALBBBBBB	12
L2-12-2	7RKVL	EM	lambda	Homo.sapiens	Hu_IGLV4-69*01	98.5	Hu_IGLV4-69*01	91.7	KLNtdgsHSKGD	BBBAALBBBBBB	10
L2-12-2	7RKSM	2.7	lambda	Homo.sapiens	Hu_IGLV4-69*01	98.5	Hu_IGLV4-69*01	91.7	KLNtdgsHSKGD	BBBAALBBBBBB	6
L2-12-2	7UAPL	EM	lambda	Homo.sapiens	Hu_IGLV4-69*01	97.1	Hu_IGLV4-69*01	83.3	SLNsdgsHTKGD	BBBAALBBBBBB	14
L2-12-2	7UAQL	EM	lambda	Homo.sapiens	Hu_IGLV4-69*01	97.1	Hu_IGLV4-69*01	83.3	SLNsdgsHTKGD	BBBAALBBBBBB	14
L2-12-2	7RKVF	EM	lambda	Homo.sapiens	Hu_IGLV4-69*01	98.5	Hu_IGLV4-69*01	91.7	KLNtdgsHSKGD	BBBAALBBBBBB	10
L2-12-2	7UAPN	EM	lambda	Homo.sapiens	Hu_IGLV4-69*01	97.1	Hu_IGLV4-69*01	83.3	SLNsdgsHTKGD	BBBAALBBBBBB	20
L2-12-2	5IHZL	1.64	lambda	Homo.sapiens	Hu_IGLV4-69*01	97.1	Hu_IGLV4-69*01	91.7	KVNsdgsHSKGD	BBBAALBBBBBB	14
L2-12-2	7UAPP	EM	lambda	Homo.sapiens	Hu_IGLV4-69*01	97.1	Hu_IGLV4-69*01	83.3	SLNsdgsHTKGD	BBBAALBBBBBB	22
L2-12-2	7RKVH	EM	lambda	Homo.sapiens	Hu_IGLV4-69*01	98.5	Hu_IGLV4-69*01	91.7	KLNtdgsHSKGD	BBBAALBBBBBB	10
L2-12-2	2GSGA	2.1	lambda	Mus.musculus	Hu_IGLV4-69*01	77.9	Hu_IGLV4-69*01	66.7	ELKKdgshSTGD	BBBAALBBBBBB	8
L2-12-2	2QHRL	2	lambda	Mus.musculus	Hu_IGLV4-69*01	79.4	Hu_IGLV4-69*01	66.7	ELKKdgshSTGD	BBBAALBBBBBB	5
L2-12-2	2GSGC	2.1	lambda	Mus.musculus	Hu_IGLV4-69*01	77.9	Hu_IGLV4-69*01	66.7	ELKKdgshSTGD	BBBAALBBBBBB	9
L2-12-2	3FFDB	2	lambda	Mus.musculus	Hu_IGLV4-69*01	77.9	Hu_IGLV4-69*01	66.7	DLKQdgshSTGD	BBBAALBBBBBB	7
L2-12-2	4ISVA	1.497	lambda	Mus.musculus	Hu_IGLV4-69*01	76.5	Hu_IGLV4-69*01	66.7	ELKKdgshSTGD	BBBAALBBBBBB	8
L2-12-2	3S96D	1.9	lambda	Mus.musculus	Hu_IGLV4-69*01	77.9	Hu_IGLV4-69*01	66.7	ELKKdgshSTGD	BBBAALBBBBBB	8
L2-12-2	4JJ5A	2.445	lambda	Mus.musculus	Hu_IGLV4-69*01	76.5	Hu_IGLV4-69*01	66.7	ELKKdgshSTGD	BBBAALBBBBBB	8
L2-12-2	6F7TA	2.6	lambda	Mus.musculus	Hu_IGLV4-69*01	77.9	Hu_IGLV4-69*01	66.7	ELKKdgshSTGD	BBBAALBBBBBB	7
L2-12-2	6LRAL	1.9	lambda	Mus.musculus	Hu_IGLV4-69*01	77.9	Hu_IGLV4-69*01	66.7	ELKKdgshSTGD	BBBAALBBBBBB	6
L2-12-2	7FGJL	1.89	lambda	Mus.musculus	Hu_IGLV4-69*01	77.9	Hu_IGLV4-69*01	66.7	ELKKdgshSTGD	BBBAALBBBBBB	7
L2-12-2	6F7TL	2.6	lambda	Mus.musculus	Hu_IGLV4-69*01	77.9	Hu_IGLV4-69*01	66.7	ELKKdgshSTGD	BBBAALBBBBBB	7
L2-12-2	7FGLL	2.1	lambda	Mus.musculus	Hu_IGLV4-69*01	77.9	Hu_IGLV4-69*01	66.7	ELKKdgshSTGD	BBBAALBBBBBB	9
L2-12-2	7FGRL	2.2	lambda	Mus.musculus	Hu_IGLV4-69*01	77.9	Hu_IGLV4-69*01	66.7	ELKKdgshSTGD	BBBAALBBBBBB	14
L2-12-2	7CR5L	2.08	lambda	Homo.sapiens	Hu_IGLV4-69*01	100.0	Hu_IGLV4-69*01	83.3	KVNSdgshTKGD	BBBAALBBBBBB	7
L2-12-2	6BE2L	1.7	lambda	Homo.sapiens	Hu_IGLV4-69*01	97.1	Hu_IGLV4-69*01	66.7	KVNRDgshiRGD	BBBAALBBBBBB	7
L2-12-2	6BE3L	1.6	lambda	Homo.sapiens	Hu_IGLV4-69*01	97.1	Hu_IGLV4-69*01	66.7	KVNRDgshiRGD	BBBAALBBBBBB	7
L2-12-2	6BE4L	1.9	lambda	Homo.sapiens	Hu_IGLV4-69*01	97.1	Hu_IGLV4-69*01	66.7	KVNRDgshiRGD	BBBAALBBBBBB	7
L2-12-2	4DCQA	1.94	lambda	Mus.musculus	Hu_IGLV4-69*01	77.3	Hu_IGLV4-69*01	66.7	ELKKdgshSTGD	BBBAALBBBBBB	9

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