PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDR Structures for L1-13-3

Summary info for L1-13-3
Loop	# of Structures	% of Loop Length	Median PDB	Consensus Sequence	# of Unique Seq	% of Unique Seq	Gene	Loop Conformation	Median Angle	Consensus Sequence Logo
L1-13-3	59	7.17	1K_5I8KL	QSSQSVyNNNrLa	18	10.00	kappa	BBABBBBLLABBB	6

Structures in cluster L1-13-3
Cluster	PDB	Resolution	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	Sequence	Ramachandran	Distance(°)
L1-13-3	6LDWL	1.6	kappa	Oryctolagus.cuniculus	Rb_IGKV1S2*01	92.5	Rb_IGKV1S2*01	84.6	QASQSVynNNWLG	BBABBBBLLABBB	4
L1-13-3	4JO1L	2.033	kappa	Oryctolagus.cuniculus	Rb_IGKV1S30*01	83.6	Rb_IGKV1S30*01	76.9	QSSQNVysNNNLA	BBABBBBLLABBB	6
L1-13-3	6LDWA	1.6	kappa	Oryctolagus.cuniculus	Rb_IGKV1S2*01	92.5	Rb_IGKV1S2*01	84.6	QASQSVynNNWLG	BBABBBBLLABBB	4
L1-13-3	4JO1M	2.033	kappa	Oryctolagus.cuniculus	Rb_IGKV1S30*01	83.6	Rb_IGKV1S30*01	76.9	QSSQNVysNNNLA	BBABBBBLLABBB	5
L1-13-3	4JO2L	2.5	kappa	Oryctolagus.cuniculus	Rb_IGKV1S30*01	83.6	Rb_IGKV1S30*01	76.9	QSSQNVysNNNLA	BBABBBBLLABBB	7
L1-13-3	4JO2M	2.5	kappa	Oryctolagus.cuniculus	Rb_IGKV1S30*01	83.6	Rb_IGKV1S30*01	76.9	QSSQNVysNNNLA	BBABBBBLLABBB	7
L1-13-3	4O51C	2.204	kappa	Oryctolagus.cuniculus.Homo.sapiens	Rb_IGKV1S9*01	89.6	Rb_IGKV1S9*01	92.3	QASQSVynKNYLA	BBABBBBLLABBB	7
L1-13-3	4O51A	2.204	kappa	Oryctolagus.cuniculus.Homo.sapiens	Rb_IGKV1S9*01	89.6	Rb_IGKV1S9*01	92.3	QASQSVynKNYLA	BBABBBBLLABBB	7
L1-13-3	4MA3L	2	kappa	Oryctolagus.cuniculus.Homo.sapiens	Rb_IGKV1S45*01	88.1	Rb_IGKV1S45*01	92.3	QASQSVynKNYLA	BBABBBBLLABBB	4
L1-13-3	4MA3A	2	kappa	Oryctolagus.cuniculus.Homo.sapiens	Rb_IGKV1S45*01	88.1	Rb_IGKV1S45*01	92.3	QASQSVynKNYLA	BBABBBBLLABBB	4
L1-13-3	4O51E	2.204	kappa	Oryctolagus.cuniculus.Homo.sapiens	Rb_IGKV1S9*01	89.6	Rb_IGKV1S9*01	92.3	QASQSVynKNYLA	BBABBBBLLABBB	8
L1-13-3	4O4YL	1.85	kappa	Oryctolagus.cuniculus.Homo.sapiens	Rb_IGKV1S45*01	88.1	Rb_IGKV1S45*01	92.3	QASQSVynKNYLA	BBABBBBLLABBB	5
L1-13-3	4O51L	2.204	kappa	Oryctolagus.cuniculus.Homo.sapiens	Rb_IGKV1S9*01	89.6	Rb_IGKV1S9*01	92.3	QASQSVynKNYLA	BBABBBBLLABBB	8
L1-13-3	5I8KL	1.771	kappa	Homo.sapiens	Rb_IGKV1S15*01	92.3	Rb_IGKV1S15*01	53.8	QSSRSVwnNNFLS	BBABBBBLLABBB	4
L1-13-3	5M63L	2.74	kappa	Oryctolagus.cuniculus	Rb_IGKV1S12*01	89.6	Rb_IGKV1S12*01	76.9	QSSQSLynNNRLA	BBABBBBLLABBB	10
L1-13-3	5M63N	2.74	kappa	Oryctolagus.cuniculus	Rb_IGKV1S12*01	89.6	Rb_IGKV1S12*01	76.9	QSSQSLynNNRLA	BBABBBBLLABBB	10
L1-13-3	6LDYB	1.77	kappa	Oryctolagus.cuniculus	Rb_IGKV1S40*01	94.0	Rb_IGKV1S40*01	61.5	QSSQNIYkdNELS	BBABBBBLLABBB	6
L1-13-3	6LDYL	1.77	kappa	Oryctolagus.cuniculus	Rb_IGKV1S40*01	94.0	Rb_IGKV1S40*01	61.5	QSSQNIYkdNELS	BBABBBBLLABBB	8
L1-13-3	6X1WL	1.95	kappa	Oryctolagus.cuniculus	Rb_IGKV1S15*01	92.3	Rb_IGKV1S15*01	53.8	QSSESIynNKNLA	BBABBBBLLABBB	11
L1-13-3	6LDVL	1.9	kappa	Oryctolagus.cuniculus	Rb_IGKV1S12*01	92.4	Rb_IGKV1S12*01	76.9	QSSQSVygNNRLA	BBABBBBLLABBB	7
L1-13-3	6X1SF	1.65	kappa	Oryctolagus.cuniculus	Rb_IGKV1S15*01	90.8	Rb_IGKV1S15*01	76.9	QASESVysNNRLS	BBABBBBLLABBB	6
L1-13-3	6X1TL	2.34	kappa	Oryctolagus.cuniculus	Rb_IGKV1S15*01	90.8	Rb_IGKV1S15*01	76.9	QASESVysNNRLS	BBABBBBLLABBB	7
L1-13-3	6X1SL	1.65	kappa	Oryctolagus.cuniculus	Rb_IGKV1S15*01	90.8	Rb_IGKV1S15*01	76.9	QASESVysNNRLS	BBABBBBLLABBB	6
L1-13-3	6I9IB	1.98	kappa	Oryctolagus.cuniculus	Rb_IGKV1S18*01	93.9	Rb_IGKV1S18*01	76.9	QASQSVYNNylLS	BBABBBBLLABBB	9
L1-13-3	6X1TI	2.34	kappa	Oryctolagus.cuniculus	Rb_IGKV1S15*01	90.8	Rb_IGKV1S15*01	76.9	QASESVysNNRLS	BBABBBBLLABBB	6
L1-13-3	6X1SB	1.65	kappa	Oryctolagus.cuniculus	Rb_IGKV1S15*01	90.8	Rb_IGKV1S15*01	76.9	QASESVysNNRLS	BBABBBBLLABBB	5
L1-13-3	6I9IL	1.98	kappa	Oryctolagus.cuniculus	Rb_IGKV1S18*01	93.9	Rb_IGKV1S18*01	76.9	QASQSVYNNylLS	BBABBBBLLABBB	9
L1-13-3	6X1TD	2.34	kappa	Oryctolagus.cuniculus	Rb_IGKV1S15*01	90.8	Rb_IGKV1S15*01	76.9	QASESVysNNRLS	BBABBBBLLABBB	6
L1-13-3	6X1SD	1.65	kappa	Oryctolagus.cuniculus	Rb_IGKV1S15*01	90.8	Rb_IGKV1S15*01	76.9	QASESVysNNRLS	BBABBBBLLABBB	5
L1-13-3	6X1TF	2.34	kappa	Oryctolagus.cuniculus	Rb_IGKV1S15*01	90.8	Rb_IGKV1S15*01	76.9	QASESVysNNRLS	BBABBBBLLABBB	7
L1-13-3	6X1VL	2.11	kappa	Oryctolagus.cuniculus	Rb_IGKV1S12*01	89.6	Rb_IGKV1S12*01	61.5	QSSQSVwrNKNLA	BBABBBBLLABBB	13
L1-13-3	6X1TK	2.34	kappa	Oryctolagus.cuniculus	Rb_IGKV1S15*01	90.8	Rb_IGKV1S15*01	76.9	QASESVysNNRLS	BBABBBBLLABBB	6
L1-13-3	5DRNB	1.994	kappa	Oryctolagus.cuniculus	Rb_IGKV1S19*01	91.0	Rb_IGKV1S19*01	53.8	QSSETVYrgDWLS	BBABBBBLLABBB	6
L1-13-3	6X1TB	2.34	kappa	Oryctolagus.cuniculus	Rb_IGKV1S15*01	90.8	Rb_IGKV1S15*01	76.9	QASESVysNNRLS	BBABBBBLLABBB	7
L1-13-3	5DRNL	1.994	kappa	Oryctolagus.cuniculus	Rb_IGKV1S19*01	91.0	Rb_IGKV1S19*01	53.8	QSSETVYrgDWLS	BBABBBBLLABBB	5
L1-13-3	5DSCF	2.4	kappa	Oryctolagus.cuniculus	Rb_IGKV1S19*01	91.0	Rb_IGKV1S19*01	46.2	RSRQRVYlgDWLS	BBABBBBLLABBB	9
L1-13-3	5DSCD	2.4	kappa	Oryctolagus.cuniculus	Rb_IGKV1S19*01	91.0	Rb_IGKV1S19*01	46.2	RSRQRVYlgDWLS	BBABBBBLLABBB	10
L1-13-3	5DSCB	2.4	kappa	Oryctolagus.cuniculus	Rb_IGKV1S19*01	91.0	Rb_IGKV1S19*01	46.2	RSRQRVYlgDWLS	BBABBBBLLABBB	9
L1-13-3	6LDXL	1.8	kappa	Oryctolagus.cuniculus	Rb_IGKV1S12*01	91.0	Rb_IGKV1S12*01	76.9	QSSQSVYNndNLA	BBABBBBLLABBB	4
L1-13-3	5DSCL	2.4	kappa	Oryctolagus.cuniculus	Rb_IGKV1S19*01	91.0	Rb_IGKV1S19*01	46.2	RSRQRVYlgDWLS	BBABBBBLLABBB	9
L1-13-3	7MFRA	2.848	kappa	Oryctolagus.cuniculus	Rb_IGKV1S12*01	87.0	Rb_IGKV1S12*01	76.9	QSSQSVytNNRLA	BBABBBBLLABBB	9
L1-13-3	7MFRX	2.848	kappa	Oryctolagus.cuniculus	Rb_IGKV1S12*01	87.0	Rb_IGKV1S12*01	76.9	QSSQSVytNNRLA	BBABBBBLLABBB	12
L1-13-3	7JWPF	3	kappa	Homo.sapiens	Rb_IGKV1S10*01	88.4	CDRLenMismatch	-1.0	QASQSVanNNYLK	BBABBBBLLABBB	6
L1-13-3	7JWQB	2.001	kappa	Homo.sapiens	Rb_IGKV1S10*01	88.4	CDRLenMismatch	-1.0	QASQSVanNNYLK	BBABBBBLLABBB	6
L1-13-3	7JWPD	3	kappa	Homo.sapiens	Rb_IGKV1S10*01	88.4	CDRLenMismatch	-1.0	QASQSVanNNYLK	BBABBBBLLABBB	6
L1-13-3	7JWQD	2.001	kappa	Homo.sapiens	Rb_IGKV1S10*01	88.4	CDRLenMismatch	-1.0	QASQSVanNNYLK	BBABBBBLLABBB	6
L1-13-3	7JWPJ	3	kappa	Homo.sapiens	Rb_IGKV1S10*01	88.4	CDRLenMismatch	-1.0	QASQSVanNNYLK	BBABBBBLLABBB	6
L1-13-3	7JWPH	3	kappa	Homo.sapiens	Rb_IGKV1S10*01	88.4	CDRLenMismatch	-1.0	QASQSVanNNYLK	BBABBBBLLABBB	6
L1-13-3	7JWPN	3	kappa	Homo.sapiens	Rb_IGKV1S10*01	88.4	CDRLenMismatch	-1.0	QASQSVanNNYLK	BBABBBBLLABBB	6
L1-13-3	7JWPL	3	kappa	Homo.sapiens	Rb_IGKV1S10*01	88.4	CDRLenMismatch	-1.0	QASQSVanNNYLK	BBABBBBLLABBB	6
L1-13-3	7JWPB	3	kappa	Homo.sapiens	Rb_IGKV1S10*01	88.4	CDRLenMismatch	-1.0	QASQSVanNNYLK	BBABBBBLLABBB	6
L1-13-3	7JWPP	3	kappa	Homo.sapiens	Rb_IGKV1S10*01	88.4	CDRLenMismatch	-1.0	QASQSVanNNYLK	BBABBBBLLABBB	6
L1-13-3	6XM2C	1.91	kappa	Homo.sapiens	Hu_IGKV3-20*01	95.5	Rb_IGKV1S12*01	92.3	QSSQSVynNNYLS	BBABBBBLLABBB	6
L1-13-3	5I8OL	1.8	kappa	Homo.sapiens	Rb_IGKV1S37*01	89.4	CDRLenMismatch	-1.0	QSSQSVygNNYLA	BBABBBBLLABBB	4
L1-13-3	6XM2A	1.91	kappa	Homo.sapiens	Hu_IGKV3-20*01	95.5	Rb_IGKV1S12*01	92.3	QSSQSVynNNYLS	BBABBBBLLABBB	5
L1-13-3	6XM2E	1.91	kappa	Homo.sapiens	Hu_IGKV3-20*01	95.5	Rb_IGKV1S12*01	92.3	QSSQSVynNNYLS	BBABBBBLLABBB	5
L1-13-3	6XM2G	1.91	kappa	Homo.sapiens	Hu_IGKV3-20*01	95.5	Rb_IGKV1S12*01	92.3	QSSQSVynNNYLS	BBABBBBLLABBB	5
L1-13-3	7RCOC	2.9	kappa	Homo.sapiens	Hu_IGKV1-27*01	92.8	CDRLenMismatch	-1.0	QSSQSVynNNYLS	BBABBBBLLABBB	7
L1-13-3	7RCOE	2.9	kappa	Homo.sapiens	Hu_IGKV1-27*01	92.8	CDRLenMismatch	-1.0	QSSQSVynNNYLS	BBABBBBLLABBB	10

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022