PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDR Structures for L1-13-2

Summary info for L1-13-2
Loop	# of Structures	% of Loop Length	Median PDB	Consensus Sequence	# of Unique Seq	% of Unique Seq	Gene	Loop Conformation	Median Angle	Consensus Sequence Logo
L1-13-2	105	12.76	2L_4YNYD	TRSSGSIaSnYVQ	16	8.89	lambda	BBABEBAAABBBB	7

Structures in cluster L1-13-2
Cluster	PDB	Resolution	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	Sequence	Ramachandran	Distance(°)
L1-13-2	4YNYB	1.584	lambda	Rattus.norvegicus	Ra_IGLV3S2*01	100.0	Ra_IGLV3S2*01	100.0	KRSTGNIGSNYVN	BBABEBAAABBBB	4
L1-13-2	4YO0B	1.56	lambda	Rattus.norvegicus	Ra_IGLV3S2*01	100.0	Ra_IGLV3S2*01	100.0	KRSTGNIGSNYVN	BBABEBAAABBBB	5
L1-13-2	4YNYD	1.584	lambda	Rattus.norvegicus	Ra_IGLV3S2*01	100.0	Ra_IGLV3S2*01	100.0	KRSTGNIGSNYVN	BBABEBAAABBBB	4
L1-13-2	5XCVB	2.143	lambda	Homo.sapiens	Ra_IGLV3S2*01	100.0	Ra_IGLV3S2*01	100.0	KRSTGNIGSNYVN	BBABEBAAABBBB	5
L1-13-2	4YO0D	1.56	lambda	Rattus.norvegicus	Ra_IGLV3S2*01	100.0	Ra_IGLV3S2*01	100.0	KRSTGNIGSNYVN	BBABEBAAABBBB	7
L1-13-2	6E62C	2.7	lambda	Rattus.norvegicus	Ra_IGLV3S2*01	92.9	Ra_IGLV3S2*01	92.3	KRSTGNIGSNYVS	BBABEBAAABBBB	10
L1-13-2	5XCVE	2.143	lambda	Homo.sapiens	Ra_IGLV3S2*01	100.0	Ra_IGLV3S2*01	100.0	KRSTGNIGSNYVN	BBABEBAAABBBB	13
L1-13-2	6E64B	3.15	lambda	Rattus.norvegicus	Ra_IGLV3S2*01	92.9	Ra_IGLV3S2*01	92.3	KRSTGNIGSNYVS	BBABEBAAABBBB	13
L1-13-2	6E62L	2.7	lambda	Rattus.norvegicus	Ra_IGLV3S2*01	92.9	Ra_IGLV3S2*01	92.3	KRSTGNIGSNYVS	BBABEBAAABBBB	10
L1-13-2	6H5NB	3.23	lambda	Rattus.norvegicus	Ra_IGLV3S2*01	94.3	Ra_IGLV3S2*01	92.3	KRSTGNIGSNYVS	BBABEBAAABBBB	11
L1-13-2	6E64L	3.15	lambda	Rattus.norvegicus	Ra_IGLV3S2*01	92.9	Ra_IGLV3S2*01	92.3	KRSTGNIGSNYVS	BBABEBAAABBBB	12
L1-13-2	6WASB	1.904	lambda	Homo.sapiens	Hu_IGLV6-57*03	85.3	Hu_IGLV6-57*03	69.2	TRSSGSIDNEYVR	BBABEBAAABBBB	6
L1-13-2	6H5NE	3.23	lambda	Rattus.norvegicus	Ra_IGLV3S2*01	94.3	Ra_IGLV3S2*01	92.3	KRSTGNIGSNYVS	BBABEBAAABBBB	18
L1-13-2	7CQCL	2.5	lambda	Rattus.norvegicus	Ra_IGLV3S2*01	100.0	Ra_IGLV3S2*01	100.0	KRSTGNIGSNYVN	BBABEBAAABBBB	8
L1-13-2	6WASL	1.904	lambda	Homo.sapiens	Hu_IGLV6-57*03	85.3	Hu_IGLV6-57*03	69.2	TRSSGSIDNEYVR	BBABEBAAABBBB	9
L1-13-2	7CQDL	3.2	lambda	Rattus.norvegicus	Ra_IGLV3S2*01	100.0	Ra_IGLV3S2*01	100.0	KRSTGNIGSNYVN	BBABEBAAABBBB	7
L1-13-2	7CQDM	3.2	lambda	Rattus.norvegicus	Ra_IGLV3S2*01	100.0	Ra_IGLV3S2*01	100.0	KRSTGNIGSNYVN	BBABEBAAABBBB	5
L1-13-2	7ZXFC	3.72	lambda	Rattus.norvegicus	Ra_IGLV3S2*01	94.3	Ra_IGLV3S2*01	92.3	KRSTGNIGSNYVS	BBABEBAAABBBB	17
L1-13-2	2W0KA	2.35	lambda	Homo.sapiens	Hu_IGLV6-57*01	100.0	Hu_IGLV6-57*01	100.0	TRSSGSIASNYVQ	BBABEBAAABBBB	13
L1-13-2	2VXSN	2.63	lambda	Homo.sapiens	Hu_IGLV6-57*01	98.6	Hu_IGLV6-57*01	76.9	TRSSGSLANYYVQ	BBABEBAAABBBB	7
L1-13-2	2W0LA	2.2	lambda	Homo.sapiens	Hu_IGLV6-57*01	98.6	Hu_IGLV6-57*01	100.0	TRSSGSIASNYVQ	BBABEBAAABBBB	5
L1-13-2	2W0LC	2.2	lambda	Homo.sapiens	Hu_IGLV6-57*01	98.6	Hu_IGLV6-57*01	100.0	TRSSGSIASNYVQ	BBABEBAAABBBB	5
L1-13-2	2VXSM	2.63	lambda	Homo.sapiens	Hu_IGLV6-57*01	98.6	Hu_IGLV6-57*01	76.9	TRSSGSLANYYVQ	BBABEBAAABBBB	9
L1-13-2	3B5GA	1.9	lambda	Homo.sapiens	Hu_IGLV6-57*01	98.6	Hu_IGLV6-57*01	100.0	TRSSGSIASNYVQ	BBABEBAAABBBB	4
L1-13-2	2W0LB	2.2	lambda	Homo.sapiens	Hu_IGLV6-57*01	98.6	Hu_IGLV6-57*01	100.0	TRSSGSIASNYVQ	BBABEBAAABBBB	6
L1-13-2	3B5GB	1.9	lambda	Homo.sapiens	Hu_IGLV6-57*01	98.6	Hu_IGLV6-57*01	100.0	TRSSGSIASNYVQ	BBABEBAAABBBB	7
L1-13-2	2W0LD	2.2	lambda	Homo.sapiens	Hu_IGLV6-57*01	98.6	Hu_IGLV6-57*01	100.0	TRSSGSIASNYVQ	BBABEBAAABBBB	6
L1-13-2	2VXSL	2.63	lambda	Homo.sapiens	Hu_IGLV6-57*01	98.6	Hu_IGLV6-57*01	76.9	TRSSGSLANYYVQ	BBABEBAAABBBB	10
L1-13-2	3BDXA	2.3	lambda	Homo.sapiens	Hu_IGLV6-57*01	98.6	Hu_IGLV6-57*01	100.0	TRSSGSIASNYVQ	BBABEBAAABBBB	7
L1-13-2	3BDXB	2.3	lambda	Homo.sapiens	Hu_IGLV6-57*01	98.6	Hu_IGLV6-57*01	100.0	TRSSGSIASNYVQ	BBABEBAAABBBB	8
L1-13-2	3H0TA	1.89	lambda	Homo.sapiens	Hu_IGLV6-57*01	100.0	Hu_IGLV6-57*01	92.3	TRSSGSIASYYVQ	BBABEBAAABBBB	7
L1-13-2	3BDXC	2.3	lambda	Homo.sapiens	Hu_IGLV6-57*01	98.6	Hu_IGLV6-57*01	100.0	TRSSGSIASNYVQ	BBABEBAAABBBB	9
L1-13-2	2VXSO	2.63	lambda	Homo.sapiens	Hu_IGLV6-57*01	98.6	Hu_IGLV6-57*01	76.9	TRSSGSLANYYVQ	BBABEBAAABBBB	11
L1-13-2	4HPOL	1.694	lambda	Homo.sapiens	Hu_IGLV6-57*03	98.6	Hu_IGLV6-57*03	84.6	TRSSGSVASDYVQ	BBABEBAAABBBB	6
L1-13-2	4HQQL	2.4	lambda	Homo.sapiens	Hu_IGLV6-57*03	98.6	Hu_IGLV6-57*03	84.6	TRSSGSVASDYVQ	BBABEBAAABBBB	6
L1-13-2	4RIRB	2.5	lambda	Homo.sapiens	Hu_IGLV6-57*01	100.0	Hu_IGLV6-57*01	100.0	TRSSGSIASNYVQ	BBABEBAAABBBB	9
L1-13-2	4RISL	2.3	lambda	Homo.sapiens	Hu_IGLV6-57*01	100.0	Hu_IGLV6-57*01	100.0	TRSSGSIASNYVQ	BBABEBAAABBBB	7
L1-13-2	4RIRL	2.5	lambda	Homo.sapiens	Hu_IGLV6-57*01	100.0	Hu_IGLV6-57*01	100.0	TRSSGSIASNYVQ	BBABEBAAABBBB	8
L1-13-2	5C9KF	1.92	lambda	Homo.sapiens	Hu_IGLV6-57*02	98.6	Hu_IGLV6-57*02	100.0	TGSSGSIASNYVQ	BBABEBAAABBBB	11
L1-13-2	5HHVL	2.2	lambda	Homo.sapiens	Hu_IGLV6-57*01	98.6	Hu_IGLV6-57*01	76.9	TRSSGSLANYYVQ	BBABEBAAABBBB	19
L1-13-2	5HI3D	2.15	lambda	Homo.sapiens	Hu_IGLV6-57*01	98.6	Hu_IGLV6-57*01	76.9	TRSSGSLANYYVQ	BBABEBAAABBBB	7
L1-13-2	5HI4D	1.8	lambda	Homo.sapiens	Hu_IGLV6-57*01	98.6	Hu_IGLV6-57*01	76.9	TRSSGSLANYYVQ	BBABEBAAABBBB	6
L1-13-2	5HI3L	2.15	lambda	Homo.sapiens	Hu_IGLV6-57*01	98.6	Hu_IGLV6-57*01	76.9	TRSSGSLANYYVQ	BBABEBAAABBBB	8
L1-13-2	5HI5D	1.8	lambda	Homo.sapiens	Hu_IGLV6-57*01	98.6	Hu_IGLV6-57*01	76.9	TRSSGSLANYYVQ	BBABEBAAABBBB	7
L1-13-2	5HI4L	1.8	lambda	Homo.sapiens	Hu_IGLV6-57*01	98.6	Hu_IGLV6-57*01	76.9	TRSSGSLANYYVQ	BBABEBAAABBBB	7
L1-13-2	5HI5L	1.8	lambda	Homo.sapiens	Hu_IGLV6-57*01	98.6	Hu_IGLV6-57*01	76.9	TRSSGSLANYYVQ	BBABEBAAABBBB	7
L1-13-2	5UTZG	2.747	lambda	Homo.sapiens	Hu_IGLV6-57*01	100.0	Hu_IGLV6-57*01	100.0	TRSSGSIASNYVQ	BBABEBAAABBBB	7
L1-13-2	6AL0L	2.6	lambda	Rattus.norvegicus	Ra_IGLV3S2*01	100.0	Ra_IGLV3S2*01	100.0	KRSTGNIGSNYVN	BBABEBAAABBBB	7
L1-13-2	5UTZC	2.747	lambda	Homo.sapiens	Hu_IGLV6-57*01	100.0	Hu_IGLV6-57*01	100.0	TRSSGSIASNYVQ	BBABEBAAABBBB	6
L1-13-2	6AL1L	3.2	lambda	Rattus.norvegicus	Ra_IGLV3S2*01	100.0	Ra_IGLV3S2*01	100.0	KRSTGNIGSNYVN	BBABEBAAABBBB	11
L1-13-2	5UTZL	2.747	lambda	Homo.sapiens	Hu_IGLV6-57*01	100.0	Hu_IGLV6-57*01	100.0	TRSSGSIASNYVQ	BBABEBAAABBBB	6
L1-13-2	6E63C	2.6	lambda	Homo.sapiens	Hu_IGLV6-57*01	98.6	Hu_IGLV6-57*01	69.2	TRSTGNIGSNYVS	BBABEBAAABBBB	6
L1-13-2	6E65L	1.5	lambda	Homo.sapiens	Hu_IGLV6-57*01	98.6	Hu_IGLV6-57*01	69.2	TRSTGNIGSNYVS	BBABEBAAABBBB	6
L1-13-2	5UTZK	2.747	lambda	Homo.sapiens	Hu_IGLV6-57*01	100.0	Hu_IGLV6-57*01	100.0	TRSSGSIASNYVQ	BBABEBAAABBBB	6
L1-13-2	6E63L	2.6	lambda	Homo.sapiens	Hu_IGLV6-57*01	98.6	Hu_IGLV6-57*01	69.2	TRSTGNIGSNYVS	BBABEBAAABBBB	8
L1-13-2	6FY3L	2.6	lambda	Homo.sapiens	Hu_IGLV6-57*01	100.0	Hu_IGLV6-57*01	92.3	TRSSGSIASDYVQ	BBABEBAAABBBB	6
L1-13-2	6FY3Y	2.6	lambda	Homo.sapiens	Hu_IGLV6-57*01	100.0	Hu_IGLV6-57*01	92.3	TRSSGSIASDYVQ	BBABEBAAABBBB	6
L1-13-2	6ICCL	2	lambda	Rattus.norvegicus	Ra_IGLV3S2*01	100.0	Ra_IGLV3S2*01	100.0	KRSTGNIGSNYVN	BBABEBAAABBBB	4
L1-13-2	6ICFL	4	lambda	Rattus.norvegicus	Ra_IGLV3S2*01	100.0	Ra_IGLV3S2*01	100.0	KRSTGNIGSNYVN	BBABEBAAABBBB	13
L1-13-2	6II4F	3.3	lambda	Homo.sapiens	Hu_IGLV6-57*01	100.0	Hu_IGLV6-57*01	100.0	TRSSGSIASNYVQ	BBABEBAAABBBB	9
L1-13-2	6II8K	3.32	lambda	Homo.sapiens	Hu_IGLV6-57*01	100.0	Hu_IGLV6-57*01	100.0	TRSSGSIASNYVQ	BBABEBAAABBBB	17
L1-13-2	6II4L	3.3	lambda	Homo.sapiens	Hu_IGLV6-57*01	100.0	Hu_IGLV6-57*01	100.0	TRSSGSIASNYVQ	BBABEBAAABBBB	10
L1-13-2	6VJNL	2	lambda	Homo.sapiens	Hu_IGLV6-57*03	89.7	Hu_IGLV6-57*03	76.9	TRTSGSIDSEYVQ	BBABEBAAABBBB	7
L1-13-2	6II8I	3.32	lambda	Homo.sapiens	Hu_IGLV6-57*01	100.0	Hu_IGLV6-57*01	100.0	TRSSGSIASNYVQ	BBABEBAAABBBB	17
L1-13-2	6XLZL	2.8	lambda	Macaca.mulatta	Ma_IGLV6-2*01	97.1	Ma_IGLV6-2*01	92.3	TRSSGSLDSEYVQ	BBABEBAAABBBB	5
L1-13-2	6II8L	3.32	lambda	Homo.sapiens	Hu_IGLV6-57*01	100.0	Hu_IGLV6-57*01	100.0	TRSSGSIASNYVQ	BBABEBAAABBBB	11
L1-13-2	7JXCL	2.47	lambda	Homo.sapiens	Hu_IGLV6-57*01	100.0	Hu_IGLV6-57*01	100.0	TRSSGSIASNYVQ	BBABEBAAABBBB	9
L1-13-2	7JX3D	2.65	lambda	Homo.sapiens	Hu_IGLV6-57*01	100.0	Hu_IGLV6-57*01	100.0	TRSSGSIASNYVQ	BBABEBAAABBBB	9
L1-13-2	7N4ML	3.79	lambda	Homo.sapiens	Hu_IGLV6-57*03	98.6	Hu_IGLV6-57*03	100.0	TRSSGSIASNYVQ	BBABEBAAABBBB	11
L1-13-2	7SD5L	1.53	lambda	Homo.sapiens	Hu_IGLV6-57*01	98.6	Hu_IGLV6-57*01	100.0	TRSSGSIASNYVQ	BBABEBAAABBBB	6
L1-13-2	7TTML	2.24	lambda	Homo.sapiens	Hu_IGLV6-57*01	98.6	Hu_IGLV6-57*01	100.0	TRSSGSIASNYVQ	BBABEBAAABBBB	6
L1-13-2	7TTXL	2.8	lambda	Homo.sapiens	Hu_IGLV6-57*01	98.6	Hu_IGLV6-57*01	100.0	TRSSGSIASNYVQ	BBABEBAAABBBB	13
L1-13-2	7TTYL	3.11	lambda	Homo.sapiens	Hu_IGLV6-57*01	98.6	Hu_IGLV6-57*01	100.0	TRSSGSIASNYVQ	BBABEBAAABBBB	16
L1-13-2	7WO7B	EM	lambda	Homo.sapiens	Hu_IGLV6-57*01	95.7	Hu_IGLV6-57*01	100.0	TRSSGSIASNYVQ	BBABEBAAABBBB	19
L1-13-2	7UMS5	EM	lambda	Homo.sapiens	Hu_IGLV6-57*02	92.8	Hu_IGLV6-57*02	100.0	TGSSGSIASNYVQ	BBABEBAAABBBB	22
L1-13-2	7UMS7	EM	lambda	Homo.sapiens	Hu_IGLV6-57*02	92.8	Hu_IGLV6-57*02	100.0	TGSSGSIASNYVQ	BBABEBAAABBBB	20
L1-13-2	7WO5G	EM	lambda	Homo.sapiens	Hu_IGLV6-57*01	95.7	Hu_IGLV6-57*01	100.0	TRSSGSIASNYVQ	BBABEBAAABBBB	17
L1-13-2	7WO4P	EM	lambda	Homo.sapiens	Hu_IGLV6-57*01	95.7	Hu_IGLV6-57*01	100.0	TRSSGSIASNYVQ	BBABEBAAABBBB	16
L1-13-2	7WO4G	EM	lambda	Homo.sapiens	Hu_IGLV6-57*01	95.7	Hu_IGLV6-57*01	100.0	TRSSGSIASNYVQ	BBABEBAAABBBB	16
L1-13-2	1CD0A	1.9	lambda	Homo.sapiens	Hu_IGLV6-57*03	94.1	Hu_IGLV6-57*03	84.6	TRSSGNIDSNYVQ	BBABEBAAABBBB	8
L1-13-2	1CD0B	1.9	lambda	Homo.sapiens	Hu_IGLV6-57*03	94.1	Hu_IGLV6-57*03	84.6	TRSSGNIDSNYVQ	BBABEBAAABBBB	5
L1-13-2	1PEWA	1.6	lambda	Homo.sapiens	Hu_IGLV6-57*03	91.2	Hu_IGLV6-57*03	92.3	TRSSGNIASNYVQ	BBABEBAAABBBB	7
L1-13-2	1PEWB	1.6	lambda	Homo.sapiens	Hu_IGLV6-57*03	91.2	Hu_IGLV6-57*03	92.3	TRSSGNIASNYVQ	BBABEBAAABBBB	8
L1-13-2	1PW3A	1.9	lambda	Homo.sapiens	Hu_IGLV6-57*03	95.6	Hu_IGLV6-57*03	84.6	TRSSGNIDSNYVQ	BBABEBAAABBBB	8
L1-13-2	1PW3B	1.9	lambda	Homo.sapiens	Hu_IGLV6-57*03	95.6	Hu_IGLV6-57*03	84.6	TRSSGNIDSNYVQ	BBABEBAAABBBB	5
L1-13-2	2CD0A	1.8	lambda	Homo.sapiens	Hu_IGLV6-57*01	95.6	Hu_IGLV6-57*01	84.6	TRSSGSIANNYVH	BBABEBAAABBBB	13
L1-13-2	2CD0B	1.8	lambda	Homo.sapiens	Hu_IGLV6-57*01	95.6	Hu_IGLV6-57*01	84.6	TRSSGSIANNYVH	BBABEBAAABBBB	16
L1-13-2	6MG4A	1.75	lambda	Homo.sapiens	Hu_IGLV6-57*03	94.1	Hu_IGLV6-57*03	84.6	TRSSGNIDSNYVQ	BBABEBAAABBBB	6
L1-13-2	6MG4B	1.75	lambda	Homo.sapiens	Hu_IGLV6-57*03	94.1	Hu_IGLV6-57*03	84.6	TRSSGNIDSNYVQ	BBABEBAAABBBB	5
L1-13-2	6MG5A	1.8	lambda	Homo.sapiens	Hu_IGLV6-57*03	94.1	Hu_IGLV6-57*03	84.6	TRSSGNIDSNYVQ	BBABEBAAABBBB	9
L1-13-2	6MG5B	1.8	lambda	Homo.sapiens	Hu_IGLV6-57*03	94.1	Hu_IGLV6-57*03	84.6	TRSSGNIDSNYVQ	BBABEBAAABBBB	5
L1-13-2	6W4YA	1.91	lambda	Homo.sapiens	Hu_IGLV6-57*03	94.1	Hu_IGLV6-57*03	84.6	TRSSGNIDSNYVQ	BBABEBAAABBBB	8
L1-13-2	6W4YB	1.91	lambda	Homo.sapiens	Hu_IGLV6-57*03	94.1	Hu_IGLV6-57*03	84.6	TRSSGNIDSNYVQ	BBABEBAAABBBB	4
L1-13-2	7LMNB	2.01	lambda	Homo.sapiens	Hu_IGLV6-57*03	94.1	Hu_IGLV6-57*03	84.6	TRSSGNIDSNYVQ	BBABEBAAABBBB	4
L1-13-2	7LMOA	1.99	lambda	Homo.sapiens	Hu_IGLV6-57*03	94.1	Hu_IGLV6-57*03	84.6	TRSSGNIDSNYVQ	BBABEBAAABBBB	5
L1-13-2	6WITL	2.79	lambda	Macaca.mulatta	Ma_IGLV6-1*01	98.5	Ma_IGLV6-1*01	100.0	TRSSGSIDSEYVQ	BBABEBAAABBBB	7
L1-13-2	7LMOB	1.99	lambda	Homo.sapiens	Hu_IGLV6-57*03	94.1	Hu_IGLV6-57*03	84.6	TRSSGNIDSNYVQ	BBABEBAAABBBB	6
L1-13-2	7LMPA	2.29	lambda	Homo.sapiens	Hu_IGLV6-57*03	94.1	Hu_IGLV6-57*03	84.6	TRSSGNIDSNYVQ	BBABEBAAABBBB	6
L1-13-2	7LMPB	2.29	lambda	Homo.sapiens	Hu_IGLV6-57*03	94.1	Hu_IGLV6-57*03	84.6	TRSSGNIDSNYVQ	BBABEBAAABBBB	7
L1-13-2	7LMQA	1.91	lambda	Homo.sapiens	Hu_IGLV6-57*03	94.1	Hu_IGLV6-57*03	84.6	TRSSGNIDSNYVQ	BBABEBAAABBBB	10
L1-13-2	7LMQB	1.91	lambda	Homo.sapiens	Hu_IGLV6-57*03	94.1	Hu_IGLV6-57*03	84.6	TRSSGNIDSNYVQ	BBABEBAAABBBB	6
L1-13-2	7LMRA	2.09	lambda	Homo.sapiens	Hu_IGLV6-57*03	94.1	Hu_IGLV6-57*03	84.6	TRSSGNIDSNYVQ	BBABEBAAABBBB	11
L1-13-2	7LMRB	2.09	lambda	Homo.sapiens	Hu_IGLV6-57*03	94.1	Hu_IGLV6-57*03	84.6	TRSSGNIDSNYVQ	BBABEBAAABBBB	5
L1-13-2	7RTPA	2.09	lambda	Homo.sapiens	Hu_IGLV6-57*03	94.1	Hu_IGLV6-57*03	84.6	TRSSGNIDSNYVQ	BBABEBAAABBBB	7
L1-13-2	7RTPB	2.09	lambda	Homo.sapiens	Hu_IGLV6-57*03	94.1	Hu_IGLV6-57*03	84.6	TRSSGNIDSNYVQ	BBABEBAAABBBB	4

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022