PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDR Structures for H4-7-1

Summary info for H4-7-1
Loop	# of Structures	% of Loop Length	Median PDB	Consensus Sequence	# of Unique Seq	% of Unique Seq	Gene	Loop Conformation	Median Angle	Consensus Sequence Logo
H4-7-1	63	86.30	4H_4ZTOI	ktSSTTV	7	70.00	heavy	BABAABB	7

Structures in cluster H4-7-1
Cluster	PDB	Resolution	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	Sequence	Ramachandran	Distance(°)
H4-7-1	4JO1H	2.033	heavy	Oryctolagus.cuniculus	Rb_IGHV1S40*01	95.7	Rb_IGHV1S40*01	100.0	KTSSTTV	BABAABB	5
H4-7-1	4JO1I	2.033	heavy	Oryctolagus.cuniculus	Rb_IGHV1S40*01	95.7	Rb_IGHV1S40*01	100.0	KTSSTTV	BABAABB	6
H4-7-1	4JO2H	2.5	heavy	Oryctolagus.cuniculus	Rb_IGHV1S40*01	95.7	Rb_IGHV1S40*01	100.0	KTSSTTV	BABAABB	12
H4-7-1	4JO2I	2.5	heavy	Oryctolagus.cuniculus	Rb_IGHV1S40*01	95.7	Rb_IGHV1S40*01	100.0	KTSSTTV	BABAABB	9
H4-7-1	7RA7A	2.2	heavy	Oryctolagus.cuniculus	Rb_IGHV1S40*01	89.9	Rb_IGHV1S40*01	100.0	KTSSTTV	BABAABB	7
H4-7-1	7RA7H	2.2	heavy	Oryctolagus.cuniculus	Rb_IGHV1S40*01	89.9	Rb_IGHV1S40*01	100.0	KTSSTTV	BABAABB	6
H4-7-1	4O51D	2.204	heavy	Oryctolagus.cuniculus.Homo.sapiens	Rb_IGHV1S69*01	92.8	Rb_IGHV1S69*01	0.0	RASSTTV	BABAABB	12
H4-7-1	4MA3H	2	heavy	Oryctolagus.cuniculus.Homo.sapiens	Rb_IGHV1S69*01	92.8	Rb_IGHV1S69*01	0.0	RASSTTV	BABAABB	6
H4-7-1	4O51B	2.204	heavy	Oryctolagus.cuniculus.Homo.sapiens	Rb_IGHV1S69*01	92.8	Rb_IGHV1S69*01	0.0	RASSTTV	BABAABB	12
H4-7-1	4O4YH	1.85	heavy	Oryctolagus.cuniculus.Homo.sapiens	Rb_IGHV1S69*01	92.8	Rb_IGHV1S69*01	0.0	RASSTTV	BABAABB	8
H4-7-1	4MA3B	2	heavy	Oryctolagus.cuniculus.Homo.sapiens	Rb_IGHV1S69*01	92.8	Rb_IGHV1S69*01	0.0	RASSTTV	BABAABB	7
H4-7-1	4O51F	2.204	heavy	Oryctolagus.cuniculus.Homo.sapiens	Rb_IGHV1S69*01	92.8	Rb_IGHV1S69*01	0.0	RASSTTV	BABAABB	12
H4-7-1	4O51H	2.204	heavy	Oryctolagus.cuniculus.Homo.sapiens	Rb_IGHV1S69*01	92.8	Rb_IGHV1S69*01	0.0	RASSTTV	BABAABB	12
H4-7-1	6VO0I	EM	heavy	Oryctolagus.cuniculus	Rb_IGHV1S45*01	88.6	Rb_IGHV1S45*01	100.0	KTSSTTV	BABAABB	11
H4-7-1	6CJKB	1.795	heavy	Oryctolagus.cuniculus	Rb_IGHV1S40*01	94.2	Rb_IGHV1S40*01	100.0	KTSSTTV	BABAABB	4
H4-7-1	6VO0H	EM	heavy	Oryctolagus.cuniculus	Rb_IGHV1S45*01	88.6	Rb_IGHV1S45*01	100.0	KTSSTTV	BABAABB	11
H4-7-1	6CJKD	1.795	heavy	Oryctolagus.cuniculus	Rb_IGHV1S40*01	94.2	Rb_IGHV1S40*01	100.0	KTSSTTV	BABAABB	5
H4-7-1	6VO0G	EM	heavy	Oryctolagus.cuniculus	Rb_IGHV1S45*01	88.6	Rb_IGHV1S45*01	100.0	KTSSTTV	BABAABB	11
H4-7-1	6DIDL	EM	heavy	Oryctolagus.cuniculus	Rb_IGHV1S40*01	94.2	Rb_IGHV1S40*01	100.0	KTSSTTV	BABAABB	5
H4-7-1	6X96J	EM	heavy	Oryctolagus.cuniculus	Rb_IGHV1S40*01	94.2	Rb_IGHV1S40*01	100.0	KTSSTTV	BABAABB	9
H4-7-1	6DIDD	EM	heavy	Oryctolagus.cuniculus	Rb_IGHV1S40*01	94.2	Rb_IGHV1S40*01	100.0	KTSSTTV	BABAABB	5
H4-7-1	4JO3H	2.6	heavy	Oryctolagus.cuniculus	Rb_IGHV1S40*01	98.6	Rb_IGHV1S40*01	100.0	KTSSTTV	BABAABB	7
H4-7-1	6X96E	EM	heavy	Oryctolagus.cuniculus	Rb_IGHV1S40*01	94.2	Rb_IGHV1S40*01	100.0	KTSSTTV	BABAABB	9
H4-7-1	6DIDK	EM	heavy	Oryctolagus.cuniculus	Rb_IGHV1S40*01	94.2	Rb_IGHV1S40*01	100.0	KTSSTTV	BABAABB	5
H4-7-1	4JO4H	2.27	heavy	Oryctolagus.cuniculus	Rb_IGHV1S40*01	98.6	Rb_IGHV1S40*01	100.0	KTSSTTV	BAEAABB	10
H4-7-1	4JO3I	2.6	heavy	Oryctolagus.cuniculus	Rb_IGHV1S40*01	98.6	Rb_IGHV1S40*01	100.0	KTSSTTV	BAEAABB	8
H4-7-1	6X96H	EM	heavy	Oryctolagus.cuniculus	Rb_IGHV1S40*01	94.2	Rb_IGHV1S40*01	100.0	KTSSTTV	BABAABB	9
H4-7-1	4JO4I	2.27	heavy	Oryctolagus.cuniculus	Rb_IGHV1S40*01	98.6	Rb_IGHV1S40*01	100.0	KTSSTTV	BABAABB	8
H4-7-1	6P62H	EM	heavy	Oryctolagus.cuniculus	Rb_IGHV1S40*01	92.9	Rb_IGHV1S40*01	100.0	KTSSTTV	BABAABB	13
H4-7-1	6P62C	EM	heavy	Oryctolagus.cuniculus	Rb_IGHV1S40*01	92.9	Rb_IGHV1S40*01	100.0	KTSSTTV	BABAABB	13
H4-7-1	6P62F	EM	heavy	Oryctolagus.cuniculus	Rb_IGHV1S40*01	92.9	Rb_IGHV1S40*01	100.0	KTSSTTV	BABAABB	13
H4-7-1	5M63H	2.74	heavy	Oryctolagus.cuniculus	Rb_IGHV1S40*01	100.0	Rb_IGHV1S40*01	100.0	KTSSTTV	BABAABB	8
H4-7-1	5M63M	2.74	heavy	Oryctolagus.cuniculus	Rb_IGHV1S40*01	100.0	Rb_IGHV1S40*01	100.0	KTSSTTV	BABAABB	7
H4-7-1	6PEHA	2.296	heavy	Homo.sapiens	Rb_IGHV1S40*01	94.3	Rb_IGHV1S40*01	85.7	KTSSTAV	BABAABB	11
H4-7-1	6PEHH	2.296	heavy	Homo.sapiens	Rb_IGHV1S40*01	94.3	Rb_IGHV1S40*01	85.7	KTSSTAV	BABAABB	13
H4-7-1	5V6LH	2.549	heavy	Oryctolagus.cuniculus	Rb_IGHV1S45*01	90.3	Rb_IGHV1S45*01	100.0	KTSSTTV	BABAABB	10
H4-7-1	5V6LI	2.549	heavy	Oryctolagus.cuniculus	Rb_IGHV1S45*01	90.3	Rb_IGHV1S45*01	100.0	KTSSTTV	BABAABB	10
H4-7-1	5V6MH	1.9	heavy	Oryctolagus.cuniculus	Rb_IGHV1S45*01	91.7	Rb_IGHV1S45*01	71.4	NPSSTTV	BABAABB	16
H4-7-1	4RZCE	2.723	heavy	Oryctolagus.cuniculus	Rb_IGHV1S40*01	92.8	Rb_IGHV1S40*01	85.7	KASSTTV	BABAABB	14
H4-7-1	4RZCH	2.723	heavy	Oryctolagus.cuniculus	Rb_IGHV1S40*01	92.8	Rb_IGHV1S40*01	85.7	KASSTTV	BABAABB	14
H4-7-1	4RZCA	2.723	heavy	Oryctolagus.cuniculus	Rb_IGHV1S40*01	92.8	Rb_IGHV1S40*01	85.7	KASSTTV	BABAABB	15
H4-7-1	4RZCC	2.723	heavy	Oryctolagus.cuniculus	Rb_IGHV1S40*01	92.8	Rb_IGHV1S40*01	85.7	KASSTTV	BABAABB	14
H4-7-1	7JWPE	3	heavy	Homo.sapiens	Rb_IGHV1S69*01	97.1	Rb_IGHV1S69*01	0.0	KTSPTTV	BABAABB	6
H4-7-1	7JWQA	2.001	heavy	Homo.sapiens	Rb_IGHV1S69*01	97.1	Rb_IGHV1S69*01	0.0	KTSPTTV	BABAABB	6
H4-7-1	7JWPC	3	heavy	Homo.sapiens	Rb_IGHV1S69*01	97.1	Rb_IGHV1S69*01	0.0	KTSPTTV	BABAABB	6
H4-7-1	7JWQC	2.001	heavy	Homo.sapiens	Rb_IGHV1S69*01	97.1	Rb_IGHV1S69*01	0.0	KTSPTTV	BABAABB	6
H4-7-1	7JWPI	3	heavy	Homo.sapiens	Rb_IGHV1S69*01	97.1	Rb_IGHV1S69*01	0.0	KTSPTTV	BABAABB	6
H4-7-1	7JWPG	3	heavy	Homo.sapiens	Rb_IGHV1S69*01	97.1	Rb_IGHV1S69*01	0.0	KTSPTTV	BABAABB	6
H4-7-1	7JWPM	3	heavy	Homo.sapiens	Rb_IGHV1S69*01	97.1	Rb_IGHV1S69*01	0.0	KTSPTTV	BABAABB	6
H4-7-1	7JWPK	3	heavy	Homo.sapiens	Rb_IGHV1S69*01	97.1	Rb_IGHV1S69*01	0.0	KTSPTTV	BABAABB	6
H4-7-1	7JWPA	3	heavy	Homo.sapiens	Rb_IGHV1S69*01	97.1	Rb_IGHV1S69*01	0.0	KTSPTTV	BABAABB	6
H4-7-1	7JWPO	3	heavy	Homo.sapiens	Rb_IGHV1S69*01	97.1	Rb_IGHV1S69*01	0.0	KTSPTTV	BABAABB	6
H4-7-1	5I8OH	1.8	heavy	Homo.sapiens	Rb_IGHV1S69*01	88.6	Rb_IGHV1S69*01	0.0	KTSSTTV	BABAABB	5
H4-7-1	4ZTOH	2.3	heavy	Oryctolagus.cuniculus	Rb_IGHV1S40*01	91.4	Rb_IGHV1S40*01	100.0	KTSSTTV	BABAABB	6
H4-7-1	4ZTOI	2.3	heavy	Oryctolagus.cuniculus	Rb_IGHV1S40*01	91.4	Rb_IGHV1S40*01	100.0	KTSSTTV	BABAABB	5
H4-7-1	4ZTPH	1.63	heavy	Oryctolagus.cuniculus	Rb_IGHV1S40*01	91.4	Rb_IGHV1S40*01	100.0	KTSSTTV	BABAABB	7
H4-7-1	7NKSC	3.5	heavy	Oryctolagus.cuniculus	Rb_IGHV1S45*01	95.7	Rb_IGHV1S45*01	100.0	KTSSTTV	BABAABB	16
H4-7-1	7NKSH	3.5	heavy	Oryctolagus.cuniculus	Rb_IGHV1S45*01	95.7	Rb_IGHV1S45*01	100.0	KTSSTTV	BABAABB	16
H4-7-1	7NRHH	EM	heavy	Oryctolagus.cuniculus	Rb_IGHV1S45*01	95.7	Rb_IGHV1S45*01	100.0	KTSSTTV	BABAABB	16
H4-7-1	6DBDA	1.755	heavy	Lama.glama	La_IGHV1S3*01_VHH	74.0	La_IGHV1S3*01_VHH	0.0	RENANTV	BABAABB	7
H4-7-1	6DBDC	1.755	heavy	Lama.glama	La_IGHV1S3*01_VHH	74.0	La_IGHV1S3*01_VHH	0.0	RENANTV	BABAABB	15
H4-7-1	6DBDD	1.755	heavy	Lama.glama	La_IGHV1S3*01_VHH	74.0	La_IGHV1S3*01_VHH	0.0	RENANTV	BABAABB	8
H4-7-1	6DBDB	1.755	heavy	Lama.glama	La_IGHV1S3*01_VHH	74.0	La_IGHV1S3*01_VHH	0.0	RENANTV	BABAABB	9

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022