PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDR Structures for H3-14-2

Summary info for H3-14-2
Loop	# of Structures	% of Loop Length	Median PDB	Consensus Sequence	# of Unique Seq	% of Unique Seq	Gene	Loop Conformation	Median Angle	Consensus Sequence Logo
H3-14-2	64	4.51	5H_7SHZC	ARELYyGGMwyFDv	13	3.99	heavy	BBBBBBLLBBBBAB	11

Structures in cluster H3-14-2
Cluster	PDB	Resolution	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	Sequence	Ramachandran	Distance(°)
H3-14-2	3ULUH	3.52	heavy	Homo.sapiens	Hu_IGHV5-10-1*04	97.3	Hu_IGHV5-10-1*04	100.0	ARELYQGYMDTFDS	BBBBBBLLBBBBAB	17
H3-14-2	3ULVH	3.522	heavy	Homo.sapiens	Hu_IGHV5-10-1*04	97.3	Hu_IGHV5-10-1*04	100.0	ARELYQGYMDTFDS	BBBBBBLLBBBBAB	19
H3-14-2	7RLVE	2.2	heavy	Mus.musculus	Mo_IGHV1S30*02	85.7	Mo_IGHV1S30*02	100.0	AREGHWDGDWYFDV	BBBBBBLLBBBBAB	17
H3-14-2	7RLWA	2.54	heavy	Mus.musculus	Mo_IGHV1S30*02	85.7	Mo_IGHV1S30*02	100.0	AREGHWDGDWYFDV	BBBBBBLLBBBBAB	16
H3-14-2	7RLVA	2.2	heavy	Mus.musculus	Mo_IGHV1S30*02	85.7	Mo_IGHV1S30*02	100.0	AREGHWDGDWYFDV	BBBBBBLLBBBBAB	17
H3-14-2	7RLXA	1.97	heavy	Mus.musculus	Mo_IGHV1S30*02	85.7	Mo_IGHV1S30*02	100.0	AREGHWDGDWYFDV	BBBBBBLLBBBBAB	18
H3-14-2	7RLWC	2.54	heavy	Mus.musculus	Mo_IGHV1S30*02	85.7	Mo_IGHV1S30*02	100.0	AREGHWDGDWYFDV	BBBBBBLLBBBBAB	16
H3-14-2	7RLVC	2.2	heavy	Mus.musculus	Mo_IGHV1S30*02	85.7	Mo_IGHV1S30*02	100.0	AREGHWDGDWYFDV	BBBBBBLLBBBBAB	17
H3-14-2	7RLYE	2.67	heavy	Mus.musculus	Mo_IGHV1S30*02	85.7	Mo_IGHV1S30*02	100.0	AREGHWDGDWYFDV	BBBBBBLLBBBBAB	16
H3-14-2	7RLZA	2.27	heavy	Mus.musculus	Mo_IGHV1S30*02	85.7	Mo_IGHV1S30*02	100.0	AREGHWDGDWYFDV	BBBBBBLLBBBBAB	16
H3-14-2	7RLYA	2.67	heavy	Mus.musculus	Mo_IGHV1S30*02	85.7	Mo_IGHV1S30*02	100.0	AREGHWDGDWYFDV	BBBBBBLLBBBBAB	15
H3-14-2	7RLZD	2.27	heavy	Mus.musculus	Mo_IGHV1S30*02	85.7	Mo_IGHV1S30*02	100.0	AREGHWDGDWYFDV	BBBBBBLLBBBBAB	16
H3-14-2	7RLYC	2.67	heavy	Mus.musculus	Mo_IGHV1S30*02	85.7	Mo_IGHV1S30*02	100.0	AREGHWDGDWYFDV	BBBBBBLLBBBBAB	15
H3-14-2	1IQWH	2.5	heavy	Mus.musculus	Mo_IGHV1-50*01	100.0	Mo_IGHV1-50*01	100.0	ARNRDYSNNWYFDV	BBBBBBLLBBBBAB	14
H3-14-2	1IT9H	2.8	heavy	Mus.musculus	Hu_IGHV1-46*02	89.0	Hu_IGHV1-46*02	100.0	ARNRDYSNNWYFDV	BBBBBBLLBBBBAB	16
H3-14-2	5G64H	3.715	heavy	Homo.sapiens	Hu_IGHV3-66*01	90.4	Hu_IGHV3-66*01	100.0	ARGSHYFGHWHFAV	BBBBBBLLBBBBAB	18
H3-14-2	5HYSE	2.5	heavy	Homo.sapiens	Hu_IGHV3-66*01	90.4	Hu_IGHV3-66*01	100.0	ARGSHYFGHWHFAV	BBBBBBLLBBBBAB	9
H3-14-2	5HYSH	2.5	heavy	Homo.sapiens	Hu_IGHV3-66*01	90.4	Hu_IGHV3-66*01	100.0	ARGSHYFGHWHFAV	BBBBBBLLBBBBAB	9
H3-14-2	5HYSA	2.5	heavy	Homo.sapiens	Hu_IGHV3-66*01	90.4	Hu_IGHV3-66*01	100.0	ARGSHYFGHWHFAV	BBBBBBLLBBBBAB	10
H3-14-2	5HYSC	2.5	heavy	Homo.sapiens	Hu_IGHV3-66*01	90.4	Hu_IGHV3-66*01	100.0	ARGSHYFGHWHFAV	BBBBBBLLBBBBAB	9
H3-14-2	6TCQH	2.05	heavy	Homo.sapiens	Hu_IGHV3-66*01	90.4	Hu_IGHV3-66*01	100.0	ARGSHYFGHWHFAV	BBBBBBLLBBBBAB	11
H3-14-2	6TCRH	1.45	heavy	Homo.sapiens	Hu_IGHV3-66*01	90.4	Hu_IGHV3-66*01	100.0	ARGSHYFGHWHFAV	BBBBBBLLBBBBAB	11
H3-14-2	7SHTH	EM	heavy	Homo.sapiens	Hu_IGHV3-30*02	86.3	Hu_IGHV3-30*02	100.0	AKGNNYFGHWHFAV	BBBBBBLLBBBBAB	19
H3-14-2	7SHUC	2.75	heavy	Homo.sapiens	Hu_IGHV3-30*02	86.3	Hu_IGHV3-30*02	100.0	AKGNNYFGHWHFAV	BBBBBBLLBBBBAB	11
H3-14-2	7SHTJ	EM	heavy	Homo.sapiens	Hu_IGHV3-30*02	86.3	Hu_IGHV3-30*02	100.0	AKGNNYFGHWHFAV	BBBBBBLLBBBBAB	19
H3-14-2	7SHYI	3	heavy	Homo.sapiens	Hu_IGHV3-66*01	90.4	Hu_IGHV3-66*01	100.0	ARGSHYFGHWHFAV	BBBBBBLLBBBBAB	9
H3-14-2	7SHUE	2.75	heavy	Homo.sapiens	Hu_IGHV3-30*02	86.3	Hu_IGHV3-30*02	100.0	AKGNNYFGHWHFAV	BBBBBBLLBBBBAB	11
H3-14-2	7SHZI	3	heavy	Homo.sapiens	Hu_IGHV3-66*01	90.4	Hu_IGHV3-66*01	100.0	ARGSHYFGHWHFAV	BBBBBBLLBBBBAB	9
H3-14-2	7SHYK	3	heavy	Homo.sapiens	Hu_IGHV3-66*01	90.4	Hu_IGHV3-66*01	100.0	ARGSHYFGHWHFAV	BBBBBBLLBBBBAB	9
H3-14-2	7SI0I	3	heavy	Homo.sapiens	Hu_IGHV3-66*01	89.0	Hu_IGHV3-66*01	100.0	ARGSHYFGHWHFAV	BBBBBBLLBBBBAB	11
H3-14-2	7SHZK	3	heavy	Homo.sapiens	Hu_IGHV3-66*01	90.4	Hu_IGHV3-66*01	100.0	ARGSHYFGHWHFAV	BBBBBBLLBBBBAB	8
H3-14-2	7SI0E	3	heavy	Homo.sapiens	Hu_IGHV3-66*01	89.0	Hu_IGHV3-66*01	100.0	ARGSHYFGHWHFAV	BBBBBBLLBBBBAB	11
H3-14-2	7SHYC	3	heavy	Homo.sapiens	Hu_IGHV3-66*01	90.4	Hu_IGHV3-66*01	100.0	ARGSHYFGHWHFAV	BBBBBBLLBBBBAB	9
H3-14-2	7SHZC	3	heavy	Homo.sapiens	Hu_IGHV3-66*01	90.4	Hu_IGHV3-66*01	100.0	ARGSHYFGHWHFAV	BBBBBBLLBBBBAB	9
H3-14-2	7SHYE	3	heavy	Homo.sapiens	Hu_IGHV3-66*01	90.4	Hu_IGHV3-66*01	100.0	ARGSHYFGHWHFAV	BBBBBBLLBBBBAB	9
H3-14-2	7SI0C	3	heavy	Homo.sapiens	Hu_IGHV3-66*01	89.0	Hu_IGHV3-66*01	100.0	ARGSHYFGHWHFAV	BBBBBBLLBBBBAB	12
H3-14-2	7SHZE	3	heavy	Homo.sapiens	Hu_IGHV3-66*01	90.4	Hu_IGHV3-66*01	100.0	ARGSHYFGHWHFAV	BBBBBBLLBBBBAB	9
H3-14-2	7SI0K	3	heavy	Homo.sapiens	Hu_IGHV3-66*01	89.0	Hu_IGHV3-66*01	100.0	ARGSHYFGHWHFAV	BBBBBBLLBBBBAB	10
H3-14-2	1IAIH	2.9	heavy	Mus.musculus	Mo_IGHV9-3-1*01	98.6	Mo_IGHV9-3-1*01	100.0	ARDGYYENYYAMDY	BBBBBBLLBBBBAB	13
H3-14-2	1JFQH	1.9	heavy	Mus.musculus	Mo_IGHV1-58*01	89.0	Mo_IGHV1-58*01	100.0	ARSEYYGGSYKFDY	BBBBBBBLBBBBAB	22
H3-14-2	2A6JH	2.7	heavy	Mus.musculus	Mo_IGHV1-58*01	91.8	Mo_IGHV1-58*01	100.0	ARSVYYGGSYYFDY	BBBBBBLLBBBBAB	13
H3-14-2	3NA9H	1.7	heavy	Homo.sapiens	Hu_IGHV5-10-1*04	97.3	Hu_IGHV5-10-1*04	100.0	ARELYQGYMDTFDS	BBBBBBLLBBBBAB	12
H3-14-2	3NAAH	1.7	heavy	Homo.sapiens	Hu_IGHV5-10-1*04	97.3	Hu_IGHV5-10-1*04	100.0	ARQLYQGYMDTFDS	BBBBBBLLBBBBAB	13
H3-14-2	3NABH	2.32	heavy	Homo.sapiens	Hu_IGHV5-10-1*01	98.6	Hu_IGHV5-10-1*01	100.0	ARELYQGYMDTFDS	BBBBBBLLBBBBAB	14
H3-14-2	3NACH	1.8	heavy	Homo.sapiens	Hu_IGHV5-10-1*01	98.6	Hu_IGHV5-10-1*01	100.0	ARQLYQGYMDTFDS	BBBBBBLLBBBBAB	12
H3-14-2	3NCJH	1.6	heavy	Homo.sapiens	Hu_IGHV5-10-1*04	97.3	Hu_IGHV5-10-1*04	100.0	ARQLYQGYMDTFDS	BBBBBBLLBBBBAB	14
H3-14-2	4KAQH	2.48	heavy	Homo.sapiens.Mus.musculus	Mo_IGHV1S121*01	98.4	Mo_IGHV1S121*01	0.0	ARSTYYGGDWYFNV	BBBBBBLLBBBBAB	14
H3-14-2	5F72S	1.85	heavy	Homo.sapiens	Hu_IGHV3-66*01	90.4	Hu_IGHV3-66*01	100.0	ARAYAGDGVYYADV	BBBBBBLLBBBBAB	10
H3-14-2	5F72T	1.85	heavy	Homo.sapiens	Hu_IGHV3-66*01	90.4	Hu_IGHV3-66*01	100.0	ARAYAGDGVYYADV	BBBBBBLLBBBBAB	10
H3-14-2	5VGAB	2.5	heavy	Mus.musculus	Mo_IGHV1-58*01	91.8	Mo_IGHV1-58*01	100.0	ARSVYYGGSYYFDY	BBBBBBLLBBBBAB	12
H3-14-2	6FABH	1.9	heavy	Mus.musculus	Mo_IGHV1-58*01	90.4	Mo_IGHV1-58*01	100.0	ARSEYYGGSYKFDY	BBBBBBLLBBBBAB	20
H3-14-2	6VJAH	EM	heavy	Homo.sapiens	Mo_IGHV1S121*01	98.4	Mo_IGHV1S121*01	0.0	ARSTYYGGDWYFNV	BBBBBBLLBBBBAB	12
H3-14-2	6VJAI	EM	heavy	Homo.sapiens	Mo_IGHV1S121*01	98.4	Mo_IGHV1S121*01	0.0	ARSTYYGGDWYFNV	BBBBBBLLBBBBAB	11
H3-14-2	6Y90C	EM	heavy	Mus.musculus	Mo_IGHV1S121*01	98.4	Mo_IGHV1S121*01	0.0	ARSTYYGGDWYFNV	BBBBBBLLBBBBAB	21
H3-14-2	6Y90H	EM	heavy	Mus.musculus	Mo_IGHV1S121*01	98.4	Mo_IGHV1S121*01	0.0	ARSTYYGGDWYFNV	BBBBBBLLBBBBAB	21
H3-14-2	7RAHB	2.6	heavy	Mus.musculus	Mo_IGHV5-6*01	98.6	Mo_IGHV5-6*01	100.0	AREIMRGGGYYFDY	BBBBBBLLBBBBAB	13
H3-14-2	7S8GH	2.57	heavy	Homo.sapiens	Hu_IGHV3-21*01	90.4	Hu_IGHV3-21*01	100.0	AREIRRASTWSADL	BBBBBBLLBBBBAB	10
H3-14-2	7S8Gh	2.57	heavy	Homo.sapiens	Hu_IGHV3-21*01	90.4	Hu_IGHV3-21*01	100.0	AREIRRASTWSADL	BBBBBBLLBBBBAB	13
H3-14-2	7TYVH	EM	heavy	Homo.sapiens	Hu_IGHV3-21*01	90.4	Hu_IGHV3-21*01	100.0	AREIRRASTWSADL	BBBBBBLLBBBBAB	17
H3-14-2	7TYVD	EM	heavy	Homo.sapiens	Hu_IGHV3-21*01	90.4	Hu_IGHV3-21*01	100.0	AREIRRASTWSADL	BBBBBBLLBBBBAB	16
H3-14-2	7UDSH	EM	heavy	Homo.sapiens	Hu_IGHV3-21*01	90.4	Hu_IGHV3-21*01	100.0	AREIRRASTWSADL	BBBBBBLLBBBBAB	19
H3-14-2	7TYVG	EM	heavy	Homo.sapiens	Hu_IGHV3-21*01	90.4	Hu_IGHV3-21*01	100.0	AREIRRASTWSADL	BBBBBBLLBBBBAB	15
H3-14-2	7UDSD	EM	heavy	Homo.sapiens	Hu_IGHV3-21*01	90.4	Hu_IGHV3-21*01	100.0	AREIRRASTWSADL	BBBBBBLLBBBBAB	17
H3-14-2	7UDSF	EM	heavy	Homo.sapiens	Hu_IGHV3-21*01	90.4	Hu_IGHV3-21*01	100.0	AREIRRASTWSADL	BBBBBBLLBBBBAB	19

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022