PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 7M6D

#CDRs = 8; #Clusters = 12.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	heavy	Homo.sapiens	Hu_IGHV5-51*01	93.2	Hu_IGHV5-51*01	76.9	H1	13	H1-13-*	-1	KGSGYGFITYWIG	BBBEBLAAABBBB
A	heavy	Homo.sapiens	Hu_IGHV5-51*01	93.2	Hu_IGHV5-51*01	90.0	H2	10	H2-10-1	14	IIYPGDSETR	BBBAAALBBB
A	heavy	Homo.sapiens	Hu_IGHV5-51*01	93.2	Hu_IGHV5-51*01	50.0	H3	12	H3-12-*	-1	AGGSGISTPMDV	BBBABABBBBAB
A	heavy	Homo.sapiens	Hu_IGHV5-51*01	93.2	Hu_IGHV5-51*01	87.5	H4	8	H4-8-1	11	ADKSINTA	BBAAALBB
B	kappa	Homo.sapiens	Hu_IGKV4-1*01	97.1	Hu_IGKV4-1*01	94.1	L1	17	L1-17-*	-1	KSSQSVlyssinKNYLA	BBABBBBBAAALBBBBB
B	kappa	Homo.sapiens	Hu_IGKV4-1*01	97.1	Hu_IGKV4-1*01	100.0	L2	8	L2-8-4	21	YWASTRES	BEAABBBB
B	kappa	Homo.sapiens	Hu_IGKV4-1*01	97.1	Hu_IGKV4-1*01	100.0	L3	9	L3-9-cis7-1	12	QQYYSTPYT	BBAABBbBB
B	kappa	Homo.sapiens	Hu_IGKV4-1*01	97.1	Hu_IGKV4-1*01	100.0	L4	6	L4-6-1	8	GSGTDF	EBEABB
H	heavy	Homo.sapiens	Hu_IGHV3-53*01	97.3	Hu_IGHV3-53*01	69.2	H1	13	H1-13-1	17	AASGITVVRNYMT	BBBLBBAAABBBB
H	heavy	Homo.sapiens	Hu_IGHV3-53*01	97.3	Hu_IGHV3-53*01	88.9	H2	9	H2-9-1	7	VIYSGGTTY	BBBAALBBB
H	heavy	Homo.sapiens	Hu_IGHV3-53*01	97.3	Hu_IGHV3-53*01	100.0	H3	12	H3-12-*	-1	ARDLEVVGAMDV	BBBAEAAEBLAB
H	heavy	Homo.sapiens	Hu_IGHV3-53*01	97.3	Hu_IGHV3-53*01	87.5	H4	8	H4-8-1	12	RDNSKNTM	BBAAALBB
L	kappa	Homo.sapiens	Hu_IGKV3-20*01	100.0	Hu_IGKV3-20*01	91.7	L1	12	L1-12-1	16	RASQSVpSSYLA	BBABBBBAABBB
L	kappa	Homo.sapiens	Hu_IGKV3-20*01	100.0	Hu_IGKV3-20*01	100.0	L2	8	L2-8-4	22	YGASSRAT	BEAABBBB
L	kappa	Homo.sapiens	Hu_IGKV3-20*01	100.0	Hu_IGKV3-20*01	71.4	L3	9	L3-9-2	12	QQYGSPMYT	BBAABABBB
L	kappa	Homo.sapiens	Hu_IGKV3-20*01	100.0	Hu_IGKV3-20*01	100.0	L4	6	L4-6-1	7	GSGTDF	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on July 15, 2024