PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 7E5R

#CDRs = 8; #Clusters = 15.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
D	kappa	Homo.sapiens	Hu_IGKV6D-21*02	89.7	Hu_IGKV6D-21*02	81.8	L1	11	L1-11-*	-1	RASQSISSNLH	BBBABBBABBB
D	kappa	Homo.sapiens	Hu_IGKV6D-21*02	89.7	Hu_IGKV6D-21*02	100.0	L2	8	L2-8-1	21	KYASQSIS	BLLABBBB
D	kappa	Homo.sapiens	Hu_IGKV6D-21*02	89.7	Hu_IGKV6D-21*02	28.6	L3	9	L3-9-*	-1	QQTNFWPYI	BBBABABBB
D	kappa	Homo.sapiens	Hu_IGKV6D-21*02	89.7	Hu_IGKV6D-21*02	100.0	L4	6	L4-6-1	22	GSGTDF	EBEABB
E	kappa	Homo.sapiens	Hu_IGKV6D-21*02	89.7	Hu_IGKV6D-21*02	81.8	L1	11	L1-11-*	-1	RASQSISSNLH	BBBABBBABBB
E	kappa	Homo.sapiens	Hu_IGKV6D-21*02	89.7	Hu_IGKV6D-21*02	100.0	L2	8	L2-8-1	21	KYASQSIS	BLLABBBB
E	kappa	Homo.sapiens	Hu_IGKV6D-21*02	89.7	Hu_IGKV6D-21*02	28.6	L3	9	L3-9-*	-1	QQTNFWPYI	BBBABABBB
E	kappa	Homo.sapiens	Hu_IGKV6D-21*02	89.7	Hu_IGKV6D-21*02	100.0	L4	6	L4-6-1	22	GSGTDF	EBEABB
H	kappa	Homo.sapiens	Hu_IGKV6D-21*02	89.7	Hu_IGKV6D-21*02	81.8	L1	11	L1-11-*	-1	RASQSISSNLH	BBBABBBABBB
H	kappa	Homo.sapiens	Hu_IGKV6D-21*02	89.7	Hu_IGKV6D-21*02	100.0	L2	8	L2-8-1	21	KYASQSIS	BLLABBBB
H	kappa	Homo.sapiens	Hu_IGKV6D-21*02	89.7	Hu_IGKV6D-21*02	28.6	L3	9	L3-9-*	-1	QQTNFWPYI	BBBABABBB
H	kappa	Homo.sapiens	Hu_IGKV6D-21*02	89.7	Hu_IGKV6D-21*02	100.0	L4	6	L4-6-1	22	GSGTDF	EBEABB
I	heavy	Homo.sapiens	Hu_IGHV3-30*01	100.0	Hu_IGHV3-30*01	100.0	H1	13	H1-13-*	-1	AASGFTFSSYAMH	BBBEBBAAABBBB
I	heavy	Homo.sapiens	Hu_IGHV3-30*01	100.0	Hu_IGHV3-30*01	100.0	H2	10	H2-10-*	-1	VISYDGSNKY	BBBAABBBBB
I	heavy	Homo.sapiens	Hu_IGHV3-30*01	100.0	Hu_IGHV3-30*01	100.0	H3	12	H3-12-*	-1	ARHATLMNNKDI	BBBBBLABBABB
I	heavy	Homo.sapiens	Hu_IGHV3-30*01	100.0	Hu_IGHV3-30*01	100.0	H4	8	H4-8-1	18	RDNSKNTL	BBAAALBB
K	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	100.0	L1	11	L1-11-*	-1	RASQSISSYLN	BBABBBAABBB
K	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	100.0	L2	8	L2-8-1	26	YAASSLQS	BLLABBBB
K	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	100.0	L3	9	L3-9-cis7-1	12	QQSYSTPRT	BBAABBbBB
K	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	100.0	L4	6	L4-6-1	11	GSGTDF	EBEABB
L	heavy	Homo.sapiens	Hu_IGHV1-69-2*01	86.3	Hu_IGHV1-69-2*01	69.2	H1	13	H1-13-1	21	KVSGYSFSNYYIH	BBBLBBAAABBBB
L	heavy	Homo.sapiens	Hu_IGHV1-69-2*01	86.3	Hu_IGHV1-69-2*01	40.0	H2	10	H2-10-*	-1	YIDPFNGGTS	BBBAABBBBB
L	heavy	Homo.sapiens	Hu_IGHV1-69-2*01	86.3	Hu_IGHV1-69-2*01	50.0	H3	13	H3-13-*	-1	ARSEYDPYYVMDY	BBBBABBABBBAB
L	heavy	Homo.sapiens	Hu_IGHV1-69-2*01	86.3	Hu_IGHV1-69-2*01	100.0	H4	8	H4-8-1	15	ADTSTDTA	BBAAALBB
M	heavy	Homo.sapiens	Hu_IGHV3-30*01	100.0	Hu_IGHV3-30*01	100.0	H1	13	H1-13-*	-1	AASGFTFSSYAMH	BBBEBBAAABBBB
M	heavy	Homo.sapiens	Hu_IGHV3-30*01	100.0	Hu_IGHV3-30*01	100.0	H2	10	H2-10-*	-1	VISYDGSNKY	BBBAABBBBB
M	heavy	Homo.sapiens	Hu_IGHV3-30*01	100.0	Hu_IGHV3-30*01	100.0	H3	12	H3-12-*	-1	ARHATLMNNKDI	BBBBBLABBABB
M	heavy	Homo.sapiens	Hu_IGHV3-30*01	100.0	Hu_IGHV3-30*01	100.0	H4	8	H4-8-1	18	RDNSKNTL	BBAAALBB
N	heavy	Homo.sapiens	Hu_IGHV1-69-2*01	86.3	Hu_IGHV1-69-2*01	69.2	H1	13	H1-13-1	21	KVSGYSFSNYYIH	BBBLBBAAABBBB
N	heavy	Homo.sapiens	Hu_IGHV1-69-2*01	86.3	Hu_IGHV1-69-2*01	40.0	H2	10	H2-10-*	-1	YIDPFNGGTS	BBBAABBBBB
N	heavy	Homo.sapiens	Hu_IGHV1-69-2*01	86.3	Hu_IGHV1-69-2*01	50.0	H3	13	H3-13-*	-1	ARSEYDPYYVMDY	BBBBABAABBBAB
N	heavy	Homo.sapiens	Hu_IGHV1-69-2*01	86.3	Hu_IGHV1-69-2*01	100.0	H4	8	H4-8-1	15	ADTSTDTA	BBAAALBB
O	heavy	Homo.sapiens	Hu_IGHV1-69-2*01	86.3	Hu_IGHV1-69-2*01	69.2	H1	13	H1-13-1	21	KVSGYSFSNYYIH	BBBLBBAAABBBB
O	heavy	Homo.sapiens	Hu_IGHV1-69-2*01	86.3	Hu_IGHV1-69-2*01	40.0	H2	10	H2-10-*	-1	YIDPFNGGTS	BBBAABBBBB
O	heavy	Homo.sapiens	Hu_IGHV1-69-2*01	86.3	Hu_IGHV1-69-2*01	50.0	H3	13	H3-13-*	-1	ARSEYDPYYVMDY	BBBBABAABBBAB
O	heavy	Homo.sapiens	Hu_IGHV1-69-2*01	86.3	Hu_IGHV1-69-2*01	100.0	H4	8	H4-8-1	15	ADTSTDTA	BBAAALBB
P	heavy	Homo.sapiens	Hu_IGHV1-24*01	97.1	Hu_IGHV1-24*01	76.9	H1	13	H1-13-*	-1	KVSGYTLPEVAMH	BBBLBBAAABBBB
P	heavy	Homo.sapiens	Hu_IGHV1-24*01	97.1	Hu_IGHV1-24*01	90.0	H2	10	H2-10-*	-1	GFDPEDGETM	EBBABLLBBB
P	heavy	Homo.sapiens	Hu_IGHV1-24*01	97.1	Hu_IGHV1-24*01	100.0	H3	14	H3-14-*	-1	ATTTPFSSSYWFDP	BBBBAAELBABAAB
P	heavy	Homo.sapiens	Hu_IGHV1-24*01	97.1	Hu_IGHV1-24*01	100.0	H4	8	H4-8-1	18	EDTSTDTA	BBAAALBB
Q	lambda	Homo.sapiens	Hu_IGLV1-51*01	97.0	Hu_IGLV1-51*01	100.0	L1	13	L1-13-1	13	SGSSSNIGNNYVS	BBBAAAAAABBBB
Q	lambda	Homo.sapiens	Hu_IGLV1-51*01	97.0	Hu_IGLV1-51*01	100.0	L2	8	L2-8-1	20	YDNNKRPS	BLLABBBB
Q	lambda	Homo.sapiens	Hu_IGLV1-51*01	97.0	Hu_IGLV1-51*01	100.0	L3	11	L3-11-1	14	GTWDSSLSAVV	BBBBAAALBBB
Q	lambda	Homo.sapiens	Hu_IGLV1-51*01	97.0	Hu_IGLV1-51*01	100.0	L4	6	L4-6-2	20	KSGTSA	BBEABB
R	lambda	Homo.sapiens	Hu_IGLV1-51*01	97.0	Hu_IGLV1-51*01	100.0	L1	13	L1-13-1	13	SGSSSNIGNNYVS	BBBAAAAAABBBB
R	lambda	Homo.sapiens	Hu_IGLV1-51*01	97.0	Hu_IGLV1-51*01	100.0	L2	8	L2-8-1	20	YDNNKRPS	BLLABBBB
R	lambda	Homo.sapiens	Hu_IGLV1-51*01	97.0	Hu_IGLV1-51*01	100.0	L3	11	L3-11-1	14	GTWDSSLSAVV	BBBBAAALBBB
R	lambda	Homo.sapiens	Hu_IGLV1-51*01	97.0	Hu_IGLV1-51*01	100.0	L4	6	L4-6-2	20	KSGTSA	BBEABB
S	lambda	Homo.sapiens	Hu_IGLV1-51*01	97.0	Hu_IGLV1-51*01	100.0	L1	13	L1-13-1	13	SGSSSNIGNNYVS	BBBAAAAAABBBB
S	lambda	Homo.sapiens	Hu_IGLV1-51*01	97.0	Hu_IGLV1-51*01	100.0	L2	8	L2-8-1	20	YDNNKRPS	BLLABBBB
S	lambda	Homo.sapiens	Hu_IGLV1-51*01	97.0	Hu_IGLV1-51*01	100.0	L3	11	L3-11-1	14	GTWDSSLSAVV	BBBBAAALBBB
S	lambda	Homo.sapiens	Hu_IGLV1-51*01	97.0	Hu_IGLV1-51*01	100.0	L4	6	L4-6-2	20	KSGTSA	BBEABB
T	heavy	Homo.sapiens	Hu_IGHV3-30*01	100.0	Hu_IGHV3-30*01	100.0	H1	13	H1-13-*	-1	AASGFTFSSYAMH	BBBEBBAAABBBB
T	heavy	Homo.sapiens	Hu_IGHV3-30*01	100.0	Hu_IGHV3-30*01	100.0	H2	10	H2-10-*	-1	VISYDGSNKY	BBBAABBBBB
T	heavy	Homo.sapiens	Hu_IGHV3-30*01	100.0	Hu_IGHV3-30*01	100.0	H3	12	H3-12-*	-1	ARHATLMNNKDI	BBBBBLABBABB
T	heavy	Homo.sapiens	Hu_IGHV3-30*01	100.0	Hu_IGHV3-30*01	100.0	H4	8	H4-8-1	18	RDNSKNTL	BBAAALBB
U	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	100.0	L1	11	L1-11-*	-1	RASQSISSYLN	BBABBBAABBB
U	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	100.0	L2	8	L2-8-1	26	YAASSLQS	BLLABBBB
U	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	100.0	L3	9	L3-9-cis7-1	12	QQSYSTPRT	BBAABBbBB
U	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	100.0	L4	6	L4-6-1	11	GSGTDF	EBEABB
V	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	100.0	L1	11	L1-11-*	-1	RASQSISSYLN	BBABBBAABBB
V	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	100.0	L2	8	L2-8-1	26	YAASSLQS	BLLABBBB
V	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	100.0	L3	9	L3-9-cis7-1	18	QQSYSTPRT	BBAABBbBB
V	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	100.0	L4	6	L4-6-1	11	GSGTDF	EBEABB
W	heavy	Homo.sapiens	Hu_IGHV1-24*01	97.1	Hu_IGHV1-24*01	76.9	H1	13	H1-13-*	-1	KVSGYTLPEVAMH	BBBLBBAAABBBB
W	heavy	Homo.sapiens	Hu_IGHV1-24*01	97.1	Hu_IGHV1-24*01	90.0	H2	10	H2-10-*	-1	GFDPEDGETM	EBBABLLBBB
W	heavy	Homo.sapiens	Hu_IGHV1-24*01	97.1	Hu_IGHV1-24*01	100.0	H3	14	H3-14-*	-1	ATTTPFSSSYWFDP	BBBBAAELBABAAB
W	heavy	Homo.sapiens	Hu_IGHV1-24*01	97.1	Hu_IGHV1-24*01	100.0	H4	8	H4-8-1	18	EDTSTDTA	BBAAALBB
X	heavy	Homo.sapiens	Hu_IGHV1-24*01	97.1	Hu_IGHV1-24*01	76.9	H1	13	H1-13-*	-1	KVSGYTLPEVAMH	BBBLBBAAABBBB
X	heavy	Homo.sapiens	Hu_IGHV1-24*01	97.1	Hu_IGHV1-24*01	90.0	H2	10	H2-10-*	-1	GFDPEDGETM	EBBABLLBBB
X	heavy	Homo.sapiens	Hu_IGHV1-24*01	97.1	Hu_IGHV1-24*01	100.0	H3	14	H3-14-*	-1	ATTTPFSSSYWFDP	BBBBAAELBABAAB
X	heavy	Homo.sapiens	Hu_IGHV1-24*01	97.1	Hu_IGHV1-24*01	100.0	H4	8	H4-8-1	18	EDTSTDTA	BBAAALBB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on July 15, 2024