PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 3EYO

#CDRs = 8; #Clusters = 10.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	kappa	Homo.sapiens	Hu_IGKV3-11*01	95.7	Hu_IGKV3-11*01	72.7	L1	11	L1-11-*	-1	RASQSVGGYLT	BBABBAEALBB
A	kappa	Homo.sapiens	Hu_IGKV3-11*01	95.7	Hu_IGKV3-11*01	75.0	L2	8	L2-8-1	11	FDASIRAT	BLLABBBB
A	kappa	Homo.sapiens	Hu_IGKV3-11*01	95.7	Hu_IGKV3-11*01	85.7	L3	10	L3-10-cis78-1	12	QQRSMWpPVT	BBAABBbbBB
A	kappa	Homo.sapiens	Hu_IGKV3-11*01	95.7	Hu_IGKV3-11*01	100.0	L4	6	L4-6-1	16	GSGTDF	EBEABB
B	heavy	Homo.sapiens	Hu_IGHV3-30*10	82.2	Hu_IGHV3-30*10	38.5	H1	13	H1-13-1	16	EGSGFKFGDHGIH	BBBLBBAAABBBB
B	heavy	Homo.sapiens	Hu_IGHV3-30*10	82.2	Hu_IGHV3-30*10	50.0	H2	10	H2-10-2	27	VISSDGTDER	BBBAALABBB
B	heavy	Homo.sapiens	Hu_IGHV3-30*10	82.2	Hu_IGHV3-30*10	100.0	H3	18	H3-18-*	-1	ARDGKcgggrcYSGLLDY
B	heavy	Homo.sapiens	Hu_IGHV3-30*10	82.2	Hu_IGHV3-30*10	87.5	H4	8	H4-8-1	29	RDNSKNTM	BBAAALBE
C	kappa	Homo.sapiens	Hu_IGKV3-11*01	95.7	Hu_IGKV3-11*01	72.7	L1	11	L1-11-1	13	RASQSVGGYLT	BBABBAEABBB
C	kappa	Homo.sapiens	Hu_IGKV3-11*01	95.7	Hu_IGKV3-11*01	75.0	L2	8	L2-8-1	7	FDASIRAT	BLLABBBB
C	kappa	Homo.sapiens	Hu_IGKV3-11*01	95.7	Hu_IGKV3-11*01	85.7	L3	10	L3-10-cis78-1	7	QQRSMWpPVT	BBAABBbbBB
C	kappa	Homo.sapiens	Hu_IGKV3-11*01	95.7	Hu_IGKV3-11*01	100.0	L4	6	L4-6-1	4	GSGTDF	EBEABB
D	heavy	Homo.sapiens	Hu_IGHV3-30*10	82.2	Hu_IGHV3-30*10	38.5	H1	13	H1-13-1	19	EGSGFKFGDHGIH	BBELBBAAABBBB
D	heavy	Homo.sapiens	Hu_IGHV3-30*10	82.2	Hu_IGHV3-30*10	50.0	H2	10	H2-10-2	18	VISSDGTDER	BBBAALABBB
D	heavy	Homo.sapiens	Hu_IGHV3-30*10	82.2	Hu_IGHV3-30*10	100.0	H3	18	H3-18-*	-1	ARDGKCGggrcYSGLLDY
D	heavy	Homo.sapiens	Hu_IGHV3-30*10	82.2	Hu_IGHV3-30*10	87.5	H4	8	H4-8-*	-1	RDNSKNTM	EBAAALBB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on July 15, 2024