PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 3CFK

#CDRs = 8; #Clusters = 10.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	lambda	Homo.sapiens	Mo_IGLV1*01	98.5	Mo_IGLV1*01	85.7	L1	14	L1-14-1	9	RSSSGAVTtSNYAT	BBAAEBBBAAALBB
A	lambda	Homo.sapiens	Mo_IGLV1*01	98.5	Mo_IGLV1*01	87.5	L2	8	L2-8-1	7	GGTNKRAP	BLEABBBB
A	lambda	Homo.sapiens	Mo_IGLV1*01	98.5	Mo_IGLV1*01	75.0	L3	9	L3-9-4	25	ALWNSNHLV	BBBBEABBB
A	lambda	Homo.sapiens	Mo_IGLV1*01	98.5	Mo_IGLV1*01	83.3	L4	6	L4-6-2	22	LIGDRA	BBEABB
B	heavy	Homo.sapiens	Mo_IGHV4-1*02	90.4	Mo_IGHV4-1*02	84.6	H1	13	H1-13-1	11	AASGFDFRRYWMT	BBBLBBAAABBBB
B	heavy	Homo.sapiens	Mo_IGHV4-1*02	90.4	Mo_IGHV4-1*02	90.0	H2	10	H2-10-2	15	EINPDSRTIN	BBBAALABBB
B	heavy	Homo.sapiens	Mo_IGHV4-1*02	90.4	Mo_IGHV4-1*02	50.0	H3	16	H3-16-*	-1	VRLDFdvYNHYYVLDY
B	heavy	Homo.sapiens	Mo_IGHV4-1*02	90.4	Mo_IGHV4-1*02	87.5	H4	8	H4-8-1	5	RDNAKNSL	BBAAALBB
C	lambda	Homo.sapiens	Mo_IGLV1*01	98.5	Mo_IGLV1*01	85.7	L1	14	L1-14-1	10	RSSSGAVTtSNYAT	BBAAEBBBAAALBB
C	lambda	Homo.sapiens	Mo_IGLV1*01	98.5	Mo_IGLV1*01	87.5	L2	8	L2-8-1	8	GGTNKRAP	BLEABBBB
C	lambda	Homo.sapiens	Mo_IGLV1*01	98.5	Mo_IGLV1*01	75.0	L3	9	L3-9-1	11	ALWNSNHLV	BBBBLLBBB
C	lambda	Homo.sapiens	Mo_IGLV1*01	98.5	Mo_IGLV1*01	83.3	L4	6	L4-6-2	22	LIGDRA	BBEABB
D	heavy	Homo.sapiens	Mo_IGHV4-1*02	90.4	Mo_IGHV4-1*02	84.6	H1	13	H1-13-1	11	AASGFDFRRYWMT	BBBLBBAAABBBB
D	heavy	Homo.sapiens	Mo_IGHV4-1*02	90.4	Mo_IGHV4-1*02	90.0	H2	10	H2-10-2	15	EINPDSRTIN	BBBAALABBB
D	heavy	Homo.sapiens	Mo_IGHV4-1*02	90.4	Mo_IGHV4-1*02	50.0	H3	16	H3-16-*	-1	VRLDFdvYNHYYVLDY
D	heavy	Homo.sapiens	Mo_IGHV4-1*02	90.4	Mo_IGHV4-1*02	87.5	H4	8	H4-8-1	6	RDNAKNSL	BBAAALBB
E	lambda	Homo.sapiens	Mo_IGLV1*01	98.5	Mo_IGLV1*01	85.7	L1	14	L1-14-1	9	RSSSGAVTtSNYAT	BBAAEBBBAAALBB
E	lambda	Homo.sapiens	Mo_IGLV1*01	98.5	Mo_IGLV1*01	87.5	L2	8	L2-8-1	7	GGTNKRAP	BLEABBBB
E	lambda	Homo.sapiens	Mo_IGLV1*01	98.5	Mo_IGLV1*01	75.0	L3	9	L3-9-*	-1	ALWNSNHLV	BBBBEABBB
E	lambda	Homo.sapiens	Mo_IGLV1*01	98.5	Mo_IGLV1*01	83.3	L4	6	L4-6-2	22	LIGDRA	BBEABB
F	heavy	Homo.sapiens	Mo_IGHV4-1*02	90.4	Mo_IGHV4-1*02	84.6	H1	13	H1-13-1	11	AASGFDFRRYWMT	BBBLBBAAABBBB
F	heavy	Homo.sapiens	Mo_IGHV4-1*02	90.4	Mo_IGHV4-1*02	90.0	H2	10	H2-10-2	15	EINPDSRTIN	BBBAALABBB
F	heavy	Homo.sapiens	Mo_IGHV4-1*02	90.4	Mo_IGHV4-1*02	50.0	H3	16	H3-16-*	-1	VRLDFdvYNHYYVLDY
F	heavy	Homo.sapiens	Mo_IGHV4-1*02	90.4	Mo_IGHV4-1*02	87.5	H4	8	H4-8-1	5	RDNAKNSL	BBAAALBB
G	lambda	Homo.sapiens	Mo_IGLV1*01	98.5	Mo_IGLV1*01	85.7	L1	14	L1-14-1	10	RSSSGAVTtSNYAT	BBAAEBBBAAALBB
G	lambda	Homo.sapiens	Mo_IGLV1*01	98.5	Mo_IGLV1*01	87.5	L2	8	L2-8-1	7	GGTNKRAP	BLEABBBB
G	lambda	Homo.sapiens	Mo_IGLV1*01	98.5	Mo_IGLV1*01	75.0	L3	9	L3-9-4	27	ALWNSNHLV	BBBBEABBB
G	lambda	Homo.sapiens	Mo_IGLV1*01	98.5	Mo_IGLV1*01	83.3	L4	6	L4-6-2	22	LIGDRA	BBEABB
H	heavy	Homo.sapiens	Mo_IGHV4-1*02	90.4	Mo_IGHV4-1*02	84.6	H1	13	H1-13-1	11	AASGFDFRRYWMT	BBBLBBAAABBBB
H	heavy	Homo.sapiens	Mo_IGHV4-1*02	90.4	Mo_IGHV4-1*02	90.0	H2	10	H2-10-2	16	EINPDSRTIN	BBBAALABBB
H	heavy	Homo.sapiens	Mo_IGHV4-1*02	90.4	Mo_IGHV4-1*02	50.0	H3	16	H3-16-*	-1	VRLDFdvYNHYYVLDY
H	heavy	Homo.sapiens	Mo_IGHV4-1*02	90.4	Mo_IGHV4-1*02	87.5	H4	8	H4-8-1	5	RDNAKNSL	BBAAALBB
I	heavy	Homo.sapiens	Mo_IGHV4-1*02	90.4	Mo_IGHV4-1*02	84.6	H1	13	H1-13-1	11	AASGFDFRRYWMT	BBBLBBAAABBBB
I	heavy	Homo.sapiens	Mo_IGHV4-1*02	90.4	Mo_IGHV4-1*02	90.0	H2	10	H2-10-2	17	EINPDSRTIN	BBBAALABBB
I	heavy	Homo.sapiens	Mo_IGHV4-1*02	90.4	Mo_IGHV4-1*02	50.0	H3	16	H3-16-*	-1	VRLDFdvYNHYYVLDY
I	heavy	Homo.sapiens	Mo_IGHV4-1*02	90.4	Mo_IGHV4-1*02	87.5	H4	8	H4-8-1	5	RDNAKNSL	BBAAALBB
J	lambda	Homo.sapiens	Mo_IGLV1*01	98.5	Mo_IGLV1*01	85.7	L1	14	L1-14-1	10	RSSSGAVTtSNYAT	BBAAEBBBAAALBB
J	lambda	Homo.sapiens	Mo_IGLV1*01	98.5	Mo_IGLV1*01	87.5	L2	8	L2-8-1	7	GGTNKRAP	BLEABBBB
J	lambda	Homo.sapiens	Mo_IGLV1*01	98.5	Mo_IGLV1*01	75.0	L3	9	L3-9-4	21	ALWNSNHLV	BBBBEABBB
J	lambda	Homo.sapiens	Mo_IGLV1*01	98.5	Mo_IGLV1*01	83.3	L4	6	L4-6-2	22	LIGDRA	BBEABB
K	heavy	Homo.sapiens	Mo_IGHV4-1*02	90.4	Mo_IGHV4-1*02	84.6	H1	13	H1-13-1	12	AASGFDFRRYWMT	BBBLBBAAABBBB
K	heavy	Homo.sapiens	Mo_IGHV4-1*02	90.4	Mo_IGHV4-1*02	90.0	H2	10	H2-10-2	15	EINPDSRTIN	BBBAALABBB
K	heavy	Homo.sapiens	Mo_IGHV4-1*02	90.4	Mo_IGHV4-1*02	50.0	H3	16	H3-16-*	-1	VRLDFdvYNHYYVLDY
K	heavy	Homo.sapiens	Mo_IGHV4-1*02	90.4	Mo_IGHV4-1*02	87.5	H4	8	H4-8-1	5	RDNAKNSL	BBAAALBB
L	lambda	Homo.sapiens	Mo_IGLV1*01	98.5	Mo_IGLV1*01	85.7	L1	14	L1-14-1	10	RSSSGAVTtSNYAT	BBAAEBBBAAALBB
L	lambda	Homo.sapiens	Mo_IGLV1*01	98.5	Mo_IGLV1*01	87.5	L2	8	L2-8-1	7	GGTNKRAP	BLEABBBB
L	lambda	Homo.sapiens	Mo_IGLV1*01	98.5	Mo_IGLV1*01	75.0	L3	9	L3-9-4	29	ALWNSNHLV	BBBBEABBB
L	lambda	Homo.sapiens	Mo_IGLV1*01	98.5	Mo_IGLV1*01	83.3	L4	6	L4-6-2	22	LIGDRA	BBEABB
M	lambda	Homo.sapiens	Mo_IGLV1*01	98.5	Mo_IGLV1*01	85.7	L1	14	L1-14-1	9	RSSSGAVTtSNYAT	BBAAEBBBAAALBB
M	lambda	Homo.sapiens	Mo_IGLV1*01	98.5	Mo_IGLV1*01	87.5	L2	8	L2-8-1	7	GGTNKRAP	BLEABBBB
M	lambda	Homo.sapiens	Mo_IGLV1*01	98.5	Mo_IGLV1*01	75.0	L3	9	L3-9-4	15	ALWNSNHLV	BBBBEABBB
M	lambda	Homo.sapiens	Mo_IGLV1*01	98.5	Mo_IGLV1*01	83.3	L4	6	L4-6-2	21	LIGDRA	BBEABB
N	heavy	Homo.sapiens	Mo_IGHV4-1*02	90.4	Mo_IGHV4-1*02	84.6	H1	13	H1-13-1	11	AASGFDFRRYWMT	BBBLBBAAABBBB
N	heavy	Homo.sapiens	Mo_IGHV4-1*02	90.4	Mo_IGHV4-1*02	90.0	H2	10	H2-10-2	17	EINPDSRTIN	BBBAALABBB
N	heavy	Homo.sapiens	Mo_IGHV4-1*02	90.4	Mo_IGHV4-1*02	50.0	H3	16	H3-16-*	-1	VRLDFdvYNHYYVLDY
N	heavy	Homo.sapiens	Mo_IGHV4-1*02	90.4	Mo_IGHV4-1*02	87.5	H4	8	H4-8-1	5	RDNAKNSL	BBAAALBB
O	lambda	Homo.sapiens	Mo_IGLV1*01	98.5	Mo_IGLV1*01	85.7	L1	14	L1-14-1	9	RSSSGAVTtSNYAT	BBAAEBBBAAALBB
O	lambda	Homo.sapiens	Mo_IGLV1*01	98.5	Mo_IGLV1*01	87.5	L2	8	L2-8-1	7	GGTNKRAP	BLEABBBB
O	lambda	Homo.sapiens	Mo_IGLV1*01	98.5	Mo_IGLV1*01	75.0	L3	9	L3-9-4	12	ALWNSNHLV	BBBBEABBB
O	lambda	Homo.sapiens	Mo_IGLV1*01	98.5	Mo_IGLV1*01	83.3	L4	6	L4-6-2	22	LIGDRA	BBEABB
P	heavy	Homo.sapiens	Mo_IGHV4-1*02	90.4	Mo_IGHV4-1*02	84.6	H1	13	H1-13-1	11	AASGFDFRRYWMT	BBBLBBAAABBBB
P	heavy	Homo.sapiens	Mo_IGHV4-1*02	90.4	Mo_IGHV4-1*02	90.0	H2	10	H2-10-2	16	EINPDSRTIN	BBBAALABBB
P	heavy	Homo.sapiens	Mo_IGHV4-1*02	90.4	Mo_IGHV4-1*02	50.0	H3	16	H3-16-*	-1	VRLDFdvYNHYYVLDY
P	heavy	Homo.sapiens	Mo_IGHV4-1*02	90.4	Mo_IGHV4-1*02	87.5	H4	8	H4-8-1	5	RDNAKNSL	BBAAALBB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on July 15, 2024