PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 7WCD

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	heavy	Homo.sapiens	Hu_IGHV1-2*04	100.0	Hu_IGHV1-2*04	100.0	H1	13	H1-13-1	12	KASGYTFTGYYMH	BBBLBBAAABBBB
A	heavy	Homo.sapiens	Hu_IGHV1-2*04	100.0	Hu_IGHV1-2*04	100.0	H2	10	H2-10-1	11	WINPNSGGTN	BBBAAALBBB
A	heavy	Homo.sapiens	Hu_IGHV1-2*04	100.0	Hu_IGHV1-2*04	100.0	H3	19	H3-19-*	-1	ARGWATYYdiltgYSLFDY
A	heavy	Homo.sapiens	Hu_IGHV1-2*04	100.0	Hu_IGHV1-2*04	100.0	H4	8	H4-8-1	11	RDTSISTA	BBAAALBB
B	lambda	Homo.sapiens	Hu_IGLV2-23*02	100.0	Hu_IGLV2-23*02	100.0	L1	14	L1-14-*	-1	TGTSSDVGSyNLVS	BBBAAAAAABBABB
B	lambda	Homo.sapiens	Hu_IGLV2-23*02	100.0	Hu_IGLV2-23*02	100.0	L2	8	L2-8-*	-1	YEVSKRPS	ABAABBBB
B	lambda	Homo.sapiens	Hu_IGLV2-23*02	100.0	Hu_IGLV2-23*02	88.9	L3	12	L3-12-*	-1	CSYAGSsTPHVV
B	lambda	Homo.sapiens	Hu_IGLV2-23*02	100.0	Hu_IGLV2-23*02	100.0	L4	6	L4-6-2	14	KSGNTA	BBEABB
E	heavy	Homo.sapiens	Hu_IGHV1-2*04	100.0	Hu_IGHV1-2*04	100.0	H1	13	H1-13-1	12	KASGYTFTGYYMH	BBBLBBAAABBBB
E	heavy	Homo.sapiens	Hu_IGHV1-2*04	100.0	Hu_IGHV1-2*04	100.0	H2	10	H2-10-1	11	WINPNSGGTN	BBBAAALBBB
E	heavy	Homo.sapiens	Hu_IGHV1-2*04	100.0	Hu_IGHV1-2*04	100.0	H3	19	H3-19-*	-1	ARGWATYYdiltgYSLFDY
E	heavy	Homo.sapiens	Hu_IGHV1-2*04	100.0	Hu_IGHV1-2*04	100.0	H4	8	H4-8-1	11	RDTSISTA	BBAAALBB
F	lambda	Homo.sapiens	Hu_IGLV2-23*02	100.0	Hu_IGLV2-23*02	100.0	L1	14	L1-14-*	-1	TGTSSDVGSyNLVS	BBBAAAAAABBABB
F	lambda	Homo.sapiens	Hu_IGLV2-23*02	100.0	Hu_IGLV2-23*02	100.0	L2	8	L2-8-*	-1	YEVSKRPS	ABAABBBB
F	lambda	Homo.sapiens	Hu_IGLV2-23*02	100.0	Hu_IGLV2-23*02	88.9	L3	12	L3-12-*	-1	CSYAGSsTPHVV
F	lambda	Homo.sapiens	Hu_IGLV2-23*02	100.0	Hu_IGLV2-23*02	100.0	L4	6	L4-6-2	14	KSGNTA	BBEABB
G	heavy	Homo.sapiens	Hu_IGHV1-2*04	100.0	Hu_IGHV1-2*04	100.0	H1	13	H1-13-1	12	KASGYTFTGYYMH	BBBLBBAAABBBB
G	heavy	Homo.sapiens	Hu_IGHV1-2*04	100.0	Hu_IGHV1-2*04	100.0	H2	10	H2-10-1	11	WINPNSGGTN	BBBAAALBBB
G	heavy	Homo.sapiens	Hu_IGHV1-2*04	100.0	Hu_IGHV1-2*04	100.0	H3	19	H3-19-*	-1	ARGWATYYdiltgYSLFDY
G	heavy	Homo.sapiens	Hu_IGHV1-2*04	100.0	Hu_IGHV1-2*04	100.0	H4	8	H4-8-1	11	RDTSISTA	BBAAALBB
I	lambda	Homo.sapiens	Hu_IGLV2-23*02	100.0	Hu_IGLV2-23*02	100.0	L1	14	L1-14-*	-1	TGTSSDVGSyNLVS	BBBAAAAAABBABB
I	lambda	Homo.sapiens	Hu_IGLV2-23*02	100.0	Hu_IGLV2-23*02	100.0	L2	8	L2-8-*	-1	YEVSKRPS	ABAABBBB
I	lambda	Homo.sapiens	Hu_IGLV2-23*02	100.0	Hu_IGLV2-23*02	88.9	L3	12	L3-12-*	-1	CSYAGSsTPHVV
I	lambda	Homo.sapiens	Hu_IGLV2-23*02	100.0	Hu_IGLV2-23*02	100.0	L4	6	L4-6-2	14	KSGNTA	BBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022