PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 7TPG

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
H	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Mo_IGHV5-12-1*01	46.2	H1	13	H1-13-1	21	AASGFNVYSSSIH	BBBLBBAAABBBB
H	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Mo_IGHV5-12-1*01	80.0	H2	10	H2-10-1	23	YISSYYGSTY	BBBAAALBBB
H	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	100.0	H3	16	H3-16-*	-1	ARIMFKwvSPNMAFDY
H	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	62.5	H4	8	H4-8-1	7	ADTSKNTA	BBAAALBB
L	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Mo_IGKV6-17*01	72.7	L1	11	L1-11-*	-1	RASQSVSSAVA	BBABBBAABBB
L	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Mo_IGKV6-17*01	62.5	L2	8	L2-8-1	19	YSASSLYS	BLLABBBB
L	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	57.1	L3	9	L3-9-2	15	QQSYYSLVT	BBAABABBB
L	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	83.3	L4	6	L4-6-2	16	RSGTDF	BBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022