PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 7TOW

#CDRs = 8; #Clusters = 9.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	heavy	Homo.sapiens	Hu_IGHV3-30*18	90.4	Hu_IGHV3-30*18	69.2	H1	13	H1-13-1	10	AASGFNFGDFGMH	BBBLBBAAABBBB
A	heavy	Homo.sapiens	Hu_IGHV3-30*18	90.4	Hu_IGHV3-30*18	70.0	H2	10	H2-10-2	9	VISYEGRNKN	BBBAALABBB
A	heavy	Homo.sapiens	Hu_IGHV3-30*18	90.4	Hu_IGHV3-30*18	100.0	H3	25	H3-25-*	-1	AKENrdrnydswsasYSDYYYGMDV
A	heavy	Homo.sapiens	Hu_IGHV3-30*18	90.4	Hu_IGHV3-30*18	75.0	H4	8	H4-8-1	6	RDNSRNML	BBAAALBB
B	kappa	Homo.sapiens	Hu_IGKV1-9*01	91.3	Hu_IGKV1-9*01	81.8	L1	11	L1-11-1	6	RASQGIDRYLA	BBABBAEABBB
B	kappa	Homo.sapiens	Hu_IGKV1-9*01	91.3	Hu_IGKV1-9*01	100.0	L2	8	L2-8-1	6	YAASTLQS	BLLABBBB
B	kappa	Homo.sapiens	Hu_IGKV1-9*01	91.3	Hu_IGKV1-9*01	71.4	L3	10	L3-10-*	-1	QQLSTYPtIT	BBAAABaBBB
B	kappa	Homo.sapiens	Hu_IGKV1-9*01	91.3	Hu_IGKV1-9*01	66.7	L4	6	L4-6-1	6	GSETDF	EBEABB
H	heavy	Homo.sapiens	Hu_IGHV3-30*18	90.4	Hu_IGHV3-30*18	69.2	H1	13	H1-13-1	9	AASGFNFGDFGMH	BBBLBBAAABBBB
H	heavy	Homo.sapiens	Hu_IGHV3-30*18	90.4	Hu_IGHV3-30*18	70.0	H2	10	H2-10-2	13	VISYEGRNKN	BBBAALABBB
H	heavy	Homo.sapiens	Hu_IGHV3-30*18	90.4	Hu_IGHV3-30*18	100.0	H3	25	H3-25-*	-1	AKENrdrnydswsasYSDYYYGMDV
H	heavy	Homo.sapiens	Hu_IGHV3-30*18	90.4	Hu_IGHV3-30*18	75.0	H4	8	H4-8-1	8	RDNSRNML	BBAAALBB
L	kappa	Homo.sapiens	Hu_IGKV1-9*01	91.3	Hu_IGKV1-9*01	81.8	L1	11	L1-11-1	7	RASQGIDRYLA	BBABBAEABBB
L	kappa	Homo.sapiens	Hu_IGKV1-9*01	91.3	Hu_IGKV1-9*01	100.0	L2	8	L2-8-1	5	YAASTLQS	BLLABBBB
L	kappa	Homo.sapiens	Hu_IGKV1-9*01	91.3	Hu_IGKV1-9*01	71.4	L3	10	L3-10-cis78-*	-1	QQLSTYPtIT	BBAAABaBBB
L	kappa	Homo.sapiens	Hu_IGKV1-9*01	91.3	Hu_IGKV1-9*01	66.7	L4	6	L4-6-1	6	GSETDF	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022