PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 7TLZ

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	kappa	Homo.sapiens	Hu_IGKV1-33*01	98.5	Hu_IGKV1-33*01	81.8	L1	11	L1-11-1	10	QASQDIRFYLN	BBABBAEABBB
A	kappa	Homo.sapiens	Hu_IGKV1-33*01	98.5	Hu_IGKV1-33*01	75.0	L2	8	L2-8-1	4	SDASNMET	BLEABBBB
A	kappa	Homo.sapiens	Hu_IGKV1-33*01	98.5	Hu_IGKV1-33*01	100.0	L3	9	L3-9-cis7-1	7	QQYDNlPFT	BBAABBbBB
A	kappa	Homo.sapiens	Hu_IGKV1-33*01	98.5	Hu_IGKV1-33*01	100.0	L4	6	L4-6-1	9	GSGTDF	EBEABB
B	heavy	Homo.sapiens	Hu_IGHV3-30*02	97.3	Hu_IGHV3-30*02	92.3	H1	13	H1-13-1	11	AASGFTFNSYGMH	BBBLBBAAABBBB
B	heavy	Homo.sapiens	Hu_IGHV3-30*02	97.3	Hu_IGHV3-30*02	90.0	H2	10	H2-10-2	19	FIRYDGGNKY	BBBAALABBB
B	heavy	Homo.sapiens	Hu_IGHV3-30*02	97.3	Hu_IGHV3-30*02	50.0	H3	15	H3-15-*	-1	ANLKDSrYSGSYYDY
B	heavy	Homo.sapiens	Hu_IGHV3-30*02	97.3	Hu_IGHV3-30*02	100.0	H4	8	H4-8-1	11	RDNSKNTL	BBAAALBB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022