PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 7TBF

#CDRs = 8; #Clusters = 14.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
D	heavy	Homo.sapiens	Hu_IGHV3-30*01	98.6	Hu_IGHV3-30*01	92.3	H1	13	H1-13-1	17	AASGFTFSSYAFH	BBBLBBAAABBBB
D	heavy	Homo.sapiens	Hu_IGHV3-30*01	98.6	Hu_IGHV3-30*01	90.0	H2	10	H2-10-2	9	VISYDGSNQY	BBBAALABBB
D	heavy	Homo.sapiens	Hu_IGHV3-30*01	98.6	Hu_IGHV3-30*01	100.0	H3	20	H3-20-*	-1	ARDlaiavaGTWHYYNGMDV
D	heavy	Homo.sapiens	Hu_IGHV3-30*01	98.6	Hu_IGHV3-30*01	100.0	H4	8	H4-8-1	11	RDNSKNTL	BBAAALBB
E	kappa	Homo.sapiens	Hu_IGKV1-12*01	94.2	Hu_IGKV1-12*01	100.0	L1	11	L1-11-1	21	RASQGISSWLA	BBABBAEBBBB
E	kappa	Homo.sapiens	Hu_IGKV1-12*01	94.2	Hu_IGKV1-12*01	87.5	L2	8	L2-8-1	21	YDASSLQS	BLLABBBB
E	kappa	Homo.sapiens	Hu_IGKV1-12*01	94.2	Hu_IGKV1-12*01	85.7	L3	9	L3-9-cis7-1	9	QQAKSFPIT	BBAABBbBB
E	kappa	Homo.sapiens	Hu_IGKV1-12*01	94.2	Hu_IGKV1-12*01	83.3	L4	6	L4-6-1	21	GYGTDF	EBEABB
H	heavy	Homo.sapiens	Hu_IGHV1-58*01	100.0	Hu_IGHV1-58*01	100.0	H1	13	H1-13-1	27	KASGFTFTSSAVQ	BBBLBBAABBBBB
H	heavy	Homo.sapiens	Hu_IGHV1-58*01	100.0	Hu_IGHV1-58*01	100.0	H2	10	H2-10-1	15	WIVVGSGNTN	BBBAAALBBB
H	heavy	Homo.sapiens	Hu_IGHV1-58*01	100.0	Hu_IGHV1-58*01	100.0	H3	16	H3-16-*	-1	AAPYCSggSCFDGFDI
H	heavy	Homo.sapiens	Hu_IGHV1-58*01	100.0	Hu_IGHV1-58*01	100.0	H4	8	H4-8-*	-1	RDMSTSTA	ALABLLBB
L	kappa	Homo.sapiens	Hu_IGKV3-20*01	98.6	Hu_IGKV3-20*01	100.0	L1	12	L1-12-*	-1	RASQSVSsSYLA	BBBABBBBLABB
L	kappa	Homo.sapiens	Hu_IGKV3-20*01	98.6	Hu_IGKV3-20*01	100.0	L2	8	L2-8-*	-1	YGASSRAT	AALABBBA
L	kappa	Homo.sapiens	Hu_IGKV3-20*01	98.6	Hu_IGKV3-20*01	85.7	L3	9	L3-9-cis7-1	22	QQYGNSPWT	BBAABBbBB
L	kappa	Homo.sapiens	Hu_IGKV3-20*01	98.6	Hu_IGKV3-20*01	100.0	L4	6	L4-6-3	31	GSGTDF	BBAABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022