PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 7TB8

#CDRs = 8; #Clusters = 15.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
D	heavy	Homo.sapiens	Hu_IGHV3-30*01	98.6	Hu_IGHV3-30*01	92.3	H1	13	H1-13-1	13	AASGFTFSSYAFH	BBBLBBAAABBBB
D	heavy	Homo.sapiens	Hu_IGHV3-30*01	98.6	Hu_IGHV3-30*01	90.0	H2	10	H2-10-2	8	VISYDGSNQY	BBBAALABBB
D	heavy	Homo.sapiens	Hu_IGHV3-30*01	98.6	Hu_IGHV3-30*01	100.0	H3	20	H3-20-*	-1	ARDlaiavaGTWHYYNGMDV
D	heavy	Homo.sapiens	Hu_IGHV3-30*01	98.6	Hu_IGHV3-30*01	100.0	H4	8	H4-8-1	13	RDNSKNTL	BBAAALBB
E	kappa	Homo.sapiens	Hu_IGKV1-12*01	94.2	Hu_IGKV1-12*01	100.0	L1	11	L1-11-1	20	RASQGISSWLA	BBABBAEBBBB
E	kappa	Homo.sapiens	Hu_IGKV1-12*01	94.2	Hu_IGKV1-12*01	87.5	L2	8	L2-8-1	20	YDASSLQS	BLLABBBB
E	kappa	Homo.sapiens	Hu_IGKV1-12*01	94.2	Hu_IGKV1-12*01	85.7	L3	9	L3-9-cis7-1	14	QQAKSFPIT	BBAABBbBB
E	kappa	Homo.sapiens	Hu_IGKV1-12*01	94.2	Hu_IGKV1-12*01	83.3	L4	6	L4-6-1	18	GYGTDF	EBEABB
F	heavy	Homo.sapiens	Hu_IGHV3-30*01	98.6	Hu_IGHV3-30*01	92.3	H1	13	H1-13-1	15	AASGFTFSSYAFH	BBBLBBAAABBBB
F	heavy	Homo.sapiens	Hu_IGHV3-30*01	98.6	Hu_IGHV3-30*01	90.0	H2	10	H2-10-2	8	VISYDGSNQY	BBBAALABBB
F	heavy	Homo.sapiens	Hu_IGHV3-30*01	98.6	Hu_IGHV3-30*01	100.0	H3	20	H3-20-*	-1	ARDlaiavaGTWHYYNGMDV
F	heavy	Homo.sapiens	Hu_IGHV3-30*01	98.6	Hu_IGHV3-30*01	100.0	H4	8	H4-8-1	13	RDNSKNTL	BBAAALBB
G	kappa	Homo.sapiens	Hu_IGKV1-12*01	94.2	Hu_IGKV1-12*01	100.0	L1	11	L1-11-1	17	RASQGISSWLA	BBABBAEBBBB
G	kappa	Homo.sapiens	Hu_IGKV1-12*01	94.2	Hu_IGKV1-12*01	87.5	L2	8	L2-8-1	20	YDASSLQS	BLLABBBB
G	kappa	Homo.sapiens	Hu_IGKV1-12*01	94.2	Hu_IGKV1-12*01	85.7	L3	9	L3-9-cis7-1	13	QQAKSFPIT	BBAABBbBB
G	kappa	Homo.sapiens	Hu_IGKV1-12*01	94.2	Hu_IGKV1-12*01	83.3	L4	6	L4-6-1	20	GYGTDF	EBEABB
H	heavy	Homo.sapiens	Hu_IGHV1-58*01	100.0	Hu_IGHV1-58*01	100.0	H1	13	H1-13-1	27	KASGFTFTSSAVQ	BBBLBBAABBBBB
H	heavy	Homo.sapiens	Hu_IGHV1-58*01	100.0	Hu_IGHV1-58*01	100.0	H2	10	H2-10-*	-1	WIVVGSGNTN	BBBAABBBBB
H	heavy	Homo.sapiens	Hu_IGHV1-58*01	100.0	Hu_IGHV1-58*01	100.0	H3	16	H3-16-*	-1	AAPYCSggSCFDGFDI
H	heavy	Homo.sapiens	Hu_IGHV1-58*01	100.0	Hu_IGHV1-58*01	100.0	H4	8	H4-8-*	-1	RDMSTSTA	ALABLLBB
J	heavy	Homo.sapiens	Hu_IGHV3-30*01	98.6	Hu_IGHV3-30*01	92.3	H1	13	H1-13-1	20	AASGFTFSSYAFH	BBBLBBAAABBBB
J	heavy	Homo.sapiens	Hu_IGHV3-30*01	98.6	Hu_IGHV3-30*01	90.0	H2	10	H2-10-2	7	VISYDGSNQY	BBBAALABBB
J	heavy	Homo.sapiens	Hu_IGHV3-30*01	98.6	Hu_IGHV3-30*01	100.0	H3	20	H3-20-*	-1	ARDlaiavaGTWHYYNGMDV
J	heavy	Homo.sapiens	Hu_IGHV3-30*01	98.6	Hu_IGHV3-30*01	100.0	H4	8	H4-8-1	12	RDNSKNTL	BBAAALBB
K	kappa	Homo.sapiens	Hu_IGKV1-12*01	94.2	Hu_IGKV1-12*01	100.0	L1	11	L1-11-1	22	RASQGISSWLA	BBABBAEBBBB
K	kappa	Homo.sapiens	Hu_IGKV1-12*01	94.2	Hu_IGKV1-12*01	87.5	L2	8	L2-8-1	21	YDASSLQS	BLLABBBB
K	kappa	Homo.sapiens	Hu_IGKV1-12*01	94.2	Hu_IGKV1-12*01	85.7	L3	9	L3-9-cis7-1	13	QQAKSFPIT	BBAABBbBB
K	kappa	Homo.sapiens	Hu_IGKV1-12*01	94.2	Hu_IGKV1-12*01	83.3	L4	6	L4-6-1	25	GYGTDF	EBEABB
L	kappa	Homo.sapiens	Hu_IGKV3-20*01	98.6	Hu_IGKV3-20*01	100.0	L1	12	L1-12-*	-1	RASQSVSsSYLA	BBABBBBBLABB
L	kappa	Homo.sapiens	Hu_IGKV3-20*01	98.6	Hu_IGKV3-20*01	100.0	L2	8	L2-8-*	-1	YGASSRAT	BLLABBBA
L	kappa	Homo.sapiens	Hu_IGKV3-20*01	98.6	Hu_IGKV3-20*01	85.7	L3	9	L3-9-cis7-*	-1	QQYGNSPWT	BBBEBBbBB
L	kappa	Homo.sapiens	Hu_IGKV3-20*01	98.6	Hu_IGKV3-20*01	100.0	L4	6	L4-6-*	-1	GSGTDF	BBAABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022