PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 7T3D

#CDRs = 8; #Clusters = 13.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
C	heavy	Homo.sapiens	Hu_IGHV3-23*01	93.1	Hu_IGHV3-23*01	92.3	H1	13	H1-13-1	8	AASGFTFSSFAMS	BBBLBBAAABBBB
C	heavy	Homo.sapiens	Hu_IGHV3-23*01	93.1	Hu_IGHV3-23*01	60.0	H2	10	H2-10-2	6	MISAGGGNTY	BBBAALABBB
C	heavy	Homo.sapiens	Hu_IGHV3-23*01	93.1	Hu_IGHV3-23*01	100.0	H3	15	H3-15-*	-1	AKSDSSGfQYGRREF
C	heavy	Homo.sapiens	Hu_IGHV3-23*01	93.1	Hu_IGHV3-23*01	87.5	H4	8	H4-8-1	5	RDNSKSTL	BBAAALBB
D	kappa	Homo.sapiens	Hu_IGKV1-33*01	97.1	Hu_IGKV1-33*01	72.7	L1	11	L1-11-1	8	QASQDIRIHLN	BBABBAEABBB
D	kappa	Homo.sapiens	Hu_IGKV1-33*01	97.1	Hu_IGKV1-33*01	87.5	L2	8	L2-8-1	6	YDASNLEA	BLLABBBB
D	kappa	Homo.sapiens	Hu_IGKV1-33*01	97.1	Hu_IGKV1-33*01	71.4	L3	9	L3-9-cis7-1	13	QHYHNlPRT	BBAABBbBB
D	kappa	Homo.sapiens	Hu_IGKV1-33*01	97.1	Hu_IGKV1-33*01	100.0	L4	6	L4-6-1	6	GSGTDF	EBEABB
H	heavy	Homo.sapiens	Hu_IGHV3-48*01	95.9	Hu_IGHV3-48*01	76.9	H1	13	H1-13-*	-1	VVSGFTFSTYSMN	BBAABALAABBBB
H	heavy	Homo.sapiens	Hu_IGHV3-48*01	95.9	Hu_IGHV3-48*01	70.0	H2	10	H2-10-2	10	YISSSSLSRY	BBBAALABBB
H	heavy	Homo.sapiens	Hu_IGHV3-48*01	95.9	Hu_IGHV3-48*01	50.0	H3	15	H3-15-*	-1	VRGSITWpTEYYLDY
H	heavy	Homo.sapiens	Hu_IGHV3-48*01	95.9	Hu_IGHV3-48*01	100.0	H4	8	H4-8-1	8	RDNAKNSL	BBAAALBB
J	heavy	Homo.sapiens	Hu_IGHV3-23*01	93.1	Hu_IGHV3-23*01	92.3	H1	13	H1-13-1	8	AASGFTFSSFAMS	BBBLBBAAABBBB
J	heavy	Homo.sapiens	Hu_IGHV3-23*01	93.1	Hu_IGHV3-23*01	60.0	H2	10	H2-10-2	6	MISAGGGNTY	BBBAALABBB
J	heavy	Homo.sapiens	Hu_IGHV3-23*01	93.1	Hu_IGHV3-23*01	100.0	H3	15	H3-15-*	-1	AKSDSSGfQYGRREF
J	heavy	Homo.sapiens	Hu_IGHV3-23*01	93.1	Hu_IGHV3-23*01	87.5	H4	8	H4-8-1	5	RDNSKSTL	BBAAALBB
K	heavy	Homo.sapiens	Hu_IGHV3-23*01	93.1	Hu_IGHV3-23*01	92.3	H1	13	H1-13-1	8	AASGFTFSSFAMS	BBBLBBAAABBBB
K	heavy	Homo.sapiens	Hu_IGHV3-23*01	93.1	Hu_IGHV3-23*01	60.0	H2	10	H2-10-2	6	MISAGGGNTY	BBBAALABBB
K	heavy	Homo.sapiens	Hu_IGHV3-23*01	93.1	Hu_IGHV3-23*01	100.0	H3	15	H3-15-*	-1	AKSDSSGfQYGRREF
K	heavy	Homo.sapiens	Hu_IGHV3-23*01	93.1	Hu_IGHV3-23*01	87.5	H4	8	H4-8-1	5	RDNSKSTL	BBAAALBB
L	kappa	Homo.sapiens	Hu_IGKV3-15*01	94.2	Hu_IGKV3-15*01	63.6	L1	11	L1-11-2	11	RASQTIRSDLA	BBABBALLBBB
L	kappa	Homo.sapiens	Hu_IGKV3-15*01	94.2	Hu_IGKV3-15*01	100.0	L2	8	L2-8-*	-1	YGASTRAT	ABAABBBB
L	kappa	Homo.sapiens	Hu_IGKV3-15*01	94.2	Hu_IGKV3-15*01	100.0	L3	10	L3-10-*	-1	QQYNNWPpLT	BBAABBABBB
L	kappa	Homo.sapiens	Hu_IGKV3-15*01	94.2	Hu_IGKV3-15*01	100.0	L4	6	L4-6-3	18	GSGTEF	EBAABB
M	kappa	Homo.sapiens	Hu_IGKV1-33*01	97.1	Hu_IGKV1-33*01	72.7	L1	11	L1-11-1	8	QASQDIRIHLN	BBABBAEABBB
M	kappa	Homo.sapiens	Hu_IGKV1-33*01	97.1	Hu_IGKV1-33*01	87.5	L2	8	L2-8-1	6	YDASNLEA	BLLABBBB
M	kappa	Homo.sapiens	Hu_IGKV1-33*01	97.1	Hu_IGKV1-33*01	71.4	L3	9	L3-9-cis7-1	13	QHYHNlPRT	BBAABBbBB
M	kappa	Homo.sapiens	Hu_IGKV1-33*01	97.1	Hu_IGKV1-33*01	100.0	L4	6	L4-6-1	6	GSGTDF	EBEABB
N	kappa	Homo.sapiens	Hu_IGKV1-33*01	97.1	Hu_IGKV1-33*01	72.7	L1	11	L1-11-1	8	QASQDIRIHLN	BBABBAEABBB
N	kappa	Homo.sapiens	Hu_IGKV1-33*01	97.1	Hu_IGKV1-33*01	87.5	L2	8	L2-8-1	6	YDASNLEA	BLLABBBB
N	kappa	Homo.sapiens	Hu_IGKV1-33*01	97.1	Hu_IGKV1-33*01	71.4	L3	9	L3-9-cis7-1	13	QHYHNlPRT	BBAABBbBB
N	kappa	Homo.sapiens	Hu_IGKV1-33*01	97.1	Hu_IGKV1-33*01	100.0	L4	6	L4-6-1	6	GSGTDF	EBEABB
O	heavy	Homo.sapiens	Hu_IGHV3-48*01	95.9	Hu_IGHV3-48*01	76.9	H1	13	H1-13-*	-1	VVSGFTFSTYSMN	BBAABALAABBBB
O	heavy	Homo.sapiens	Hu_IGHV3-48*01	95.9	Hu_IGHV3-48*01	70.0	H2	10	H2-10-2	10	YISSSSLSRY	BBBAALABBB
O	heavy	Homo.sapiens	Hu_IGHV3-48*01	95.9	Hu_IGHV3-48*01	50.0	H3	15	H3-15-*	-1	VRGSITWpTEYYLDY
O	heavy	Homo.sapiens	Hu_IGHV3-48*01	95.9	Hu_IGHV3-48*01	100.0	H4	8	H4-8-1	8	RDNAKNSL	BBAAALBB
P	heavy	Homo.sapiens	Hu_IGHV3-48*01	95.9	Hu_IGHV3-48*01	76.9	H1	13	H1-13-*	-1	VVSGFTFSTYSMN	BBAABALAABBBB
P	heavy	Homo.sapiens	Hu_IGHV3-48*01	95.9	Hu_IGHV3-48*01	70.0	H2	10	H2-10-2	10	YISSSSLSRY	BBBAALABBB
P	heavy	Homo.sapiens	Hu_IGHV3-48*01	95.9	Hu_IGHV3-48*01	50.0	H3	15	H3-15-*	-1	VRGSITWpTEYYLDY
P	heavy	Homo.sapiens	Hu_IGHV3-48*01	95.9	Hu_IGHV3-48*01	100.0	H4	8	H4-8-1	8	RDNAKNSL	BBAAALBB
Q	kappa	Homo.sapiens	Hu_IGKV3-15*01	94.2	Hu_IGKV3-15*01	63.6	L1	11	L1-11-2	11	RASQTIRSDLA	BBABBALLBBB
Q	kappa	Homo.sapiens	Hu_IGKV3-15*01	94.2	Hu_IGKV3-15*01	100.0	L2	8	L2-8-*	-1	YGASTRAT	ABAABBBB
Q	kappa	Homo.sapiens	Hu_IGKV3-15*01	94.2	Hu_IGKV3-15*01	100.0	L3	10	L3-10-*	-1	QQYNNWPpLT	BBAABBABBB
Q	kappa	Homo.sapiens	Hu_IGKV3-15*01	94.2	Hu_IGKV3-15*01	100.0	L4	6	L4-6-3	18	GSGTEF	EBAABB
R	kappa	Homo.sapiens	Hu_IGKV3-15*01	94.2	Hu_IGKV3-15*01	63.6	L1	11	L1-11-2	11	RASQTIRSDLA	BBABBALLBBB
R	kappa	Homo.sapiens	Hu_IGKV3-15*01	94.2	Hu_IGKV3-15*01	100.0	L2	8	L2-8-*	-1	YGASTRAT	ABAABBBB
R	kappa	Homo.sapiens	Hu_IGKV3-15*01	94.2	Hu_IGKV3-15*01	100.0	L3	10	L3-10-*	-1	QQYNNWPpLT	BBAABBABBB
R	kappa	Homo.sapiens	Hu_IGKV3-15*01	94.2	Hu_IGKV3-15*01	100.0	L4	6	L4-6-3	18	GSGTEF	EBAABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022