PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 7S8H

#CDRs = 8; #Clusters = 13.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
B	heavy	Homo.sapiens	Hu_IGHV4-34*09	89.0	Hu_IGHV4-34*09	69.2	H1	13	H1-13-*	-1	AVSGGPFSGAYWT	BBBLBBBBLBBBB
B	heavy	Homo.sapiens	Hu_IGHV4-34*09	89.0	Hu_IGHV4-34*09	55.6	H2	9	H2-9-1	14	EAGRSGTTN	BBBAALBBB
B	heavy	Homo.sapiens	Hu_IGHV4-34*09	89.0	Hu_IGHV4-34*09	50.0	H3	18	H3-18-*	-1	GRRQIMSlsnlYKRPVDS
B	heavy	Homo.sapiens	Hu_IGHV4-34*09	89.0	Hu_IGHV4-34*09	75.0	H4	8	H4-8-*	-1	LDTSKSQF	ALAAALBB
C	kappa	Homo.sapiens	Hu_IGKV3-20*01	95.7	Hu_IGKV3-20*01	75.0	L1	12	L1-12-2	10	RASQSVtKNYLA	BBABBBBLLBBB
C	kappa	Homo.sapiens	Hu_IGKV3-20*01	95.7	Hu_IGKV3-20*01	62.5	L2	8	L2-8-1	11	YDASTRAS	BLLABBBB
C	kappa	Homo.sapiens	Hu_IGKV3-20*01	95.7	Hu_IGKV3-20*01	85.7	L3	10	L3-10-cis78-*	-1	HQYGSSpPYT	BBAABBBbBB
C	kappa	Homo.sapiens	Hu_IGKV3-20*01	95.7	Hu_IGKV3-20*01	100.0	L4	6	L4-6-1	15	GSGTDF	EBEABB
H	heavy	Homo.sapiens	Hu_IGHV3-21*01	89.0	Hu_IGHV3-21*01	84.6	H1	13	H1-13-1	14	AAAGFTFKSYSMN	BBBLBBAAABBBB
H	heavy	Homo.sapiens	Hu_IGHV3-21*01	89.0	Hu_IGHV3-21*01	50.0	H2	10	H2-10-2	8	SITSGGSKTY	BBBAALABBB
H	heavy	Homo.sapiens	Hu_IGHV3-21*01	89.0	Hu_IGHV3-21*01	100.0	H3	15	H3-15-*	-1	ARSLHSTsQPSYMDV
H	heavy	Homo.sapiens	Hu_IGHV3-21*01	89.0	Hu_IGHV3-21*01	87.5	H4	8	H4-8-1	8	RDNAKQSL	BBAAALBB
L	kappa	Homo.sapiens	Hu_IGKV3-20*01	91.3	Hu_IGKV3-20*01	75.0	L1	12	L1-12-1	13	RASQSViSYYVA	BBABBBBAAABB
L	kappa	Homo.sapiens	Hu_IGKV3-20*01	91.3	Hu_IGKV3-20*01	100.0	L2	8	L2-8-1	6	YGASSRAT	BLLABBBB
L	kappa	Homo.sapiens	Hu_IGKV3-20*01	91.3	Hu_IGKV3-20*01	85.7	L3	10	L3-10-cis78-*	-1	QYYGSSPlWA	BBBLBBbABB
L	kappa	Homo.sapiens	Hu_IGKV3-20*01	91.3	Hu_IGKV3-20*01	100.0	L4	6	L4-6-1	7	GSGTDF	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022