PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 7S5R

#CDRs = 8; #Clusters = 10.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
B	heavy	Homo.sapiens	Hu_IGHV1-58*02	98.6	Hu_IGHV1-58*02	100.0	H1	13	H1-13-1	17	KASGFTFTSSAMQ	BBBLBBAAABBBB
B	heavy	Homo.sapiens	Hu_IGHV1-58*02	98.6	Hu_IGHV1-58*02	100.0	H2	10	H2-10-1	8	WIVVGSGNTN	BBBAAALBBB
B	heavy	Homo.sapiens	Hu_IGHV1-58*02	98.6	Hu_IGHV1-58*02	100.0	H3	16	H3-16-*	-1	AAPYcsSTNCYDAFDI
B	heavy	Homo.sapiens	Hu_IGHV1-58*02	98.6	Hu_IGHV1-58*02	100.0	H4	8	H4-8-1	10	RDMSTSTA	BBAAALBB
C	kappa	Homo.sapiens	Hu_IGKV3-20*01	100.0	Hu_IGKV3-20*01	100.0	L1	12	L1-12-1	8	RASQSVSsSYLA	BBABBBBAAABB
C	kappa	Homo.sapiens	Hu_IGKV3-20*01	100.0	Hu_IGKV3-20*01	100.0	L2	8	L2-8-1	12	YGASSRAT	BLLABBBB
C	kappa	Homo.sapiens	Hu_IGKV3-20*01	100.0	Hu_IGKV3-20*01	100.0	L3	9	L3-9-cis7-1	22	QQYGSSPWT	BBAABBbBB
C	kappa	Homo.sapiens	Hu_IGKV3-20*01	100.0	Hu_IGKV3-20*01	100.0	L4	6	L4-6-1	14	GSGTDF	EBEABB
H	heavy	Homo.sapiens	Hu_IGHV1-46*01	100.0	Hu_IGHV1-46*01	100.0	H1	13	H1-13-1	6	KASGYTFTSYYMH	BBBLBBAAABBBB
H	heavy	Homo.sapiens	Hu_IGHV1-46*01	100.0	Hu_IGHV1-46*01	90.0	H2	10	H2-10-1	9	IINSSGGSTS	BBBAAALBBB
H	heavy	Homo.sapiens	Hu_IGHV1-46*01	100.0	Hu_IGHV1-46*01	100.0	H3	22	H3-22-*	-1	ARpprnyydrSGYYQRAEYFQH
H	heavy	Homo.sapiens	Hu_IGHV1-46*01	100.0	Hu_IGHV1-46*01	100.0	H4	8	H4-8-1	3	RDTSTSTV	BBAAALBB
L	kappa	Homo.sapiens	Hu_IGKV1-33*01	97.1	Hu_IGKV1-33*01	100.0	L1	11	L1-11-1	8	QASQDISNYLN	BBABBAEABBB
L	kappa	Homo.sapiens	Hu_IGKV1-33*01	97.1	Hu_IGKV1-33*01	100.0	L2	8	L2-8-1	9	YDASNLET	BLLABBBB
L	kappa	Homo.sapiens	Hu_IGKV1-33*01	97.1	Hu_IGKV1-33*01	85.7	L3	9	L3-9-cis7-1	9	QQYDNPpLT	BBAABBbBB
L	kappa	Homo.sapiens	Hu_IGKV1-33*01	97.1	Hu_IGKV1-33*01	100.0	L4	6	L4-6-1	15	GSGTDF	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022