PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 7RPU

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	heavy	Homo.sapiens	Hu_IGHV3-21*01	93.2	Hu_IGHV3-21*01	76.9	H1	13	H1-13-1	8	AASGFTFNEYMMN	BBBLBBAAABBBB
A	heavy	Homo.sapiens	Hu_IGHV3-21*01	93.2	Hu_IGHV3-21*01	60.0	H2	10	H2-10-2	11	SISGTSTYIN	BBBAALABBB
A	heavy	Homo.sapiens	Hu_IGHV3-21*01	93.2	Hu_IGHV3-21*01	100.0	H3	8	H3-8-2	19	ARGSTGGY	BBEAALAB
A	heavy	Homo.sapiens	Hu_IGHV3-21*01	93.2	Hu_IGHV3-21*01	100.0	H4	8	H4-8-1	3	RDNAKNSL	BBAAALBB
B	kappa	Homo.sapiens	Hu_IGKV2-24*01	95.7	Hu_IGKV2-24*01	93.8	L1	16	L1-16-*	-1	RSSQRLvhsdgNTYLS	BBABBBBBAALBBBBB
B	kappa	Homo.sapiens	Hu_IGKV2-24*01	95.7	Hu_IGKV2-24*01	75.0	L2	8	L2-8-1	3	YKVSLRFS	BLLABBBB
B	kappa	Homo.sapiens	Hu_IGKV2-24*01	95.7	Hu_IGKV2-24*01	100.0	L3	9	L3-9-cis7-1	7	MQATQFPLT	BBAABBbBB
B	kappa	Homo.sapiens	Hu_IGKV2-24*01	95.7	Hu_IGKV2-24*01	100.0	L4	6	L4-6-1	7	GAGTDF	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022