PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 7QEZ

#CDRs = 8; #Clusters = 13.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
E	heavy	Homo.sapiens	Hu_IGHV5-51*01	93.2	Hu_IGHV5-51*01	76.9	H1	13	H1-13-*	-1	KGSGYGFITYWIG	BBBEBLAAABBBB
E	heavy	Homo.sapiens	Hu_IGHV5-51*01	93.2	Hu_IGHV5-51*01	90.0	H2	10	H2-10-*	-1	IIYPGDSETR	BBBAABABBB
E	heavy	Homo.sapiens	Hu_IGHV5-51*01	93.2	Hu_IGHV5-51*01	50.0	H3	12	H3-12-*	-1	AGGSGISTPMDV	BBBABAABBBAB
E	heavy	Homo.sapiens	Hu_IGHV5-51*01	93.2	Hu_IGHV5-51*01	87.5	H4	8	H4-8-1	9	ADKSINTA	BBAAALBB
F	kappa	Homo.sapiens	Hu_IGKV4-1*01	97.1	Hu_IGKV4-1*01	94.1	L1	17	L1-17-1	9	KSSQSVlyssinKNYLA	BBABBABBAAALBBBBB
F	kappa	Homo.sapiens	Hu_IGKV4-1*01	97.1	Hu_IGKV4-1*01	100.0	L2	8	L2-8-*	-1	YWASTRES	BLLABBBA
F	kappa	Homo.sapiens	Hu_IGKV4-1*01	97.1	Hu_IGKV4-1*01	100.0	L3	9	L3-9-cis7-1	10	QQYYSTPYT	BBAABBbBB
F	kappa	Homo.sapiens	Hu_IGKV4-1*01	97.1	Hu_IGKV4-1*01	100.0	L4	6	L4-6-1	7	GSGTDF	EBEABB
H	heavy	Homo.sapiens	Hu_IGHV1-58*01	97.3	Hu_IGHV1-58*01	92.3	H1	13	H1-13-1	21	KASGFTFTTSAVQ	BBBLBBAAABBBB
H	heavy	Homo.sapiens	Hu_IGHV1-58*01	97.3	Hu_IGHV1-58*01	100.0	H2	10	H2-10-1	10	WIVVGSGNTN	BBBAAALBBB
H	heavy	Homo.sapiens	Hu_IGHV1-58*01	97.3	Hu_IGHV1-58*01	100.0	H3	16	H3-16-*	-1	AAPYCSggTCLDGFDI
H	heavy	Homo.sapiens	Hu_IGHV1-58*01	97.3	Hu_IGHV1-58*01	87.5	H4	8	H4-8-1	9	RDMSTTTA	BBAAALBB
L	kappa	Homo.sapiens	Hu_IGKV3-20*01	100.0	Hu_IGKV3-20*01	91.7	L1	12	L1-12-1	15	RASQSVSrSYLA	BBABBBBAAABB
L	kappa	Homo.sapiens	Hu_IGKV3-20*01	100.0	Hu_IGKV3-20*01	87.5	L2	8	L2-8-*	-1	YSASSRAT	BEBLBBBB
L	kappa	Homo.sapiens	Hu_IGKV3-20*01	100.0	Hu_IGKV3-20*01	100.0	L3	9	L3-9-2	17	QQYGSSPWT	BBBABABBB
L	kappa	Homo.sapiens	Hu_IGKV3-20*01	100.0	Hu_IGKV3-20*01	100.0	L4	6	L4-6-1	20	GSGTDF	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022