PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 7Q4Q

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	kappa	Mus.musculus	Hu_IGKV4-1*01	91.3	Mo_IGKV3-7*01	86.7	L1	15	L1-15-1	11	RASQSVSTsgysFMH	BBABBABBLLBBBBB
A	kappa	Mus.musculus	Hu_IGKV4-1*01	91.3	Mo_IGKV3-7*01	100.0	L2	8	L2-8-1	9	KYASNLES	BLLABBBB
A	kappa	Mus.musculus	Hu_IGKV4-1*01	91.3	Hu_IGKV4-1*01	28.6	L3	9	L3-9-cis7-1	11	QHSWEMPLT	BBAABBbBB
A	kappa	Mus.musculus	Hu_IGKV4-1*01	91.3	Hu_IGKV4-1*01	100.0	L4	6	L4-6-1	7	GSGTDF	EBEABB
B	heavy	Mus.musculus	Hu_IGHV1-69*17	94.5	Mo_IGHV1-80*01	84.6	H1	13	H1-13-1	6	KASGYTFSGYWMN	BBBLBBAAABBBB
B	heavy	Mus.musculus	Hu_IGHV1-69*17	94.5	Mo_IGHV1-80*01	100.0	H2	10	H2-10-1	8	QIYPGDGDTN	BBBAAALBBB
B	heavy	Mus.musculus	Hu_IGHV1-69*17	94.5	Hu_IGHV1-69*17	100.0	H3	11	H3-11-1	15	ARSITTVVLDY	BBBBAALBBAB
B	heavy	Mus.musculus	Hu_IGHV1-69*17	94.5	Hu_IGHV1-69*17	100.0	H4	8	H4-8-1	6	ADKSTSTA	BBAAALBB
C	kappa	Mus.musculus	Hu_IGKV4-1*01	91.3	Mo_IGKV3-7*01	86.7	L1	15	L1-15-1	9	RASQSVSTsgysFMH	BBABBABBLLBBBBB
C	kappa	Mus.musculus	Hu_IGKV4-1*01	91.3	Mo_IGKV3-7*01	100.0	L2	8	L2-8-1	9	KYASNLES	BLLABBBB
C	kappa	Mus.musculus	Hu_IGKV4-1*01	91.3	Hu_IGKV4-1*01	28.6	L3	9	L3-9-cis7-1	10	QHSWEMPLT	BBAABBbBB
C	kappa	Mus.musculus	Hu_IGKV4-1*01	91.3	Hu_IGKV4-1*01	100.0	L4	6	L4-6-1	5	GSGTDF	EBEABB
D	heavy	Mus.musculus	Hu_IGHV1-69*17	94.5	Mo_IGHV1-80*01	84.6	H1	13	H1-13-1	8	KASGYTFSGYWMN	BBBLBBAAABBBB
D	heavy	Mus.musculus	Hu_IGHV1-69*17	94.5	Mo_IGHV1-80*01	100.0	H2	10	H2-10-1	7	QIYPGDGDTN	BBBAAALBBB
D	heavy	Mus.musculus	Hu_IGHV1-69*17	94.5	Hu_IGHV1-69*17	100.0	H3	11	H3-11-1	15	ARSITTVVLDY	BBBBAALBBAB
D	heavy	Mus.musculus	Hu_IGHV1-69*17	94.5	Hu_IGHV1-69*17	100.0	H4	8	H4-8-1	8	ADKSTSTA	BBAAALBB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022