PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 7PHP

#CDRs = 8; #Clusters = 13.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
H	heavy	Synthetic.construct	Hu_IGHV3-48*01	91.8	Hu_IGHV3-48*01	69.2	H1	13	H1-13-1	13	AASGFNFSYYSIH	BBBLBBAAABBBB
H	heavy	Synthetic.construct	Hu_IGHV3-48*01	91.8	Hu_IGHV3-48*01	70.0	H2	10	H2-10-*	-1	YISSSSSYTS	BBBABAABBB
H	heavy	Synthetic.construct	Hu_IGHV3-48*01	91.8	Hu_IGHV3-48*01	100.0	H3	21	H3-21-*	-1	ARGYQYWQYHAswywnggLDY
H	heavy	Synthetic.construct	Hu_IGHV3-48*01	91.8	Hu_IGHV3-48*01	37.5	H4	8	H4-8-1	12	ADTSKNTA	BBAAALBB
K	heavy	Lama.glama	La_IGHV1S3*01_VHH	90.4	La_IGHV1S3*01_VHH	61.5	H1	13	H1-13-1	15	AASGRTISRYAMS	BBBLBBAAABBBB
K	heavy	Lama.glama	La_IGHV1S3*01_VHH	90.4	CDRLenMismatch	-1.0	H2	10	H2-10-*	-1	VARRSGDGAF	BBBBBLAEBB
K	heavy	Lama.glama	La_IGHV1S3*01_VHH	90.4	La_IGHV1S3*01_VHH	0.0	H3	14	H3-14-*	-1	AIDSDTFYSGSYDY	BBBABAALALBBAB
K	heavy	Lama.glama	La_IGHV1S3*01_VHH	90.4	La_IGHV1S3*01_VHH	87.5	H4	8	H4-8-1	16	RDDAKNTV	BBAAALBB
L	kappa	Synthetic.construct	Hu_IGKV1D-13*01	97.1	Hu_IGKV1D-13*01	72.7	L1	11	L1-11-*	-1	RASQSVSSAVA	BBBBAABALBB
L	kappa	Synthetic.construct	Hu_IGKV1D-13*01	97.1	Hu_IGKV1D-13*01	75.0	L2	8	L2-8-1	18	YSASSLYS	BLLABBBB
L	kappa	Synthetic.construct	Hu_IGKV1D-13*01	97.1	Hu_IGKV1D-13*01	28.6	L3	9	L3-9-*	-1	QQSSSSLIT	BBBBAABBB
L	kappa	Synthetic.construct	Hu_IGKV1D-13*01	97.1	Hu_IGKV1D-13*01	83.3	L4	6	L4-6-2	18	RSGTDF	BBEABB
N	heavy	Synthetic.construct	Al_IGHV3S53*01_VHH	90.4	Al_IGHV3S53*01_VHH	76.9	H1	13	H1-13-*	-1	AASGIIFKINDMG	BBBLBALAABBBE
N	heavy	Synthetic.construct	Al_IGHV3S53*01_VHH	90.4	Al_IGHV3S53*01_VHH	77.8	H2	9	H2-9-*	-1	GITSGGRTN	EBBLAELBB
N	heavy	Synthetic.construct	Al_IGHV3S53*01_VHH	90.4	Al_IGHV3S53*01_VHH	0.0	H3	16	H3-16-*	-1	KSDGLISYaaSQLSTY
N	heavy	Synthetic.construct	Al_IGHV3S53*01_VHH	90.4	Al_IGHV3S53*01_VHH	87.5	H4	8	H4-8-*	-1	RDNVKNTV	BBAABBBB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022