PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 7NCS

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
H	heavy	Homo.sapiens	Ra_IGHV5-54*01	84.9	Ra_IGHV5-54*01	92.3	H1	13	H1-13-*	-1	VASRFTFSNYGMN	BBAABALABLBBB
H	heavy	Homo.sapiens	Ra_IGHV5-54*01	84.9	Ra_IGHV5-54*01	40.0	H2	10	H2-10-*	-1	YIGSTSSHIY	BBBLBAABBB
H	heavy	Homo.sapiens	Ra_IGHV5-54*01	84.9	Ra_IGHV5-54*01	0.0	H3	13	H3-13-*	-1	VGHVRKLGAFFDY	BBBBBLAELBBAB
H	heavy	Homo.sapiens	Ra_IGHV5-54*01	84.9	Ra_IGHV5-54*01	87.5	H4	8	H4-8-1	6	RDNAKNTL	BBAAALBB
L	kappa	Homo.sapiens	Ra_IGKV12S34*01	98.6	Ra_IGKV12S34*01	72.7	L1	11	L1-11-*	-1	RASEDIHSRLA	BBAALBBLABB
L	kappa	Homo.sapiens	Ra_IGKV12S34*01	98.6	Ra_IGKV12S34*01	100.0	L2	8	L2-8-1	19	YNANSLHT	BLLABBBB
L	kappa	Homo.sapiens	Ra_IGKV12S34*01	98.6	Ra_IGKV12S34*01	85.7	L3	10	L3-10-*	-1	LQYYNYpPYT	BBAABAABBB
L	kappa	Homo.sapiens	Ra_IGKV12S34*01	98.6	Ra_IGKV12S34*01	83.3	L4	6	L4-6-3	33	GSGTQF	EBAABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022