PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 7N8H

#CDRs = 8; #Clusters = 12.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
B	kappa	Homo.sapiens	Hu_IGKV1-33*01	98.5	Hu_IGKV1-33*01	81.8	L1	11	L1-11-1	8	QASQDIRFYLN	BBABBAEABBB
B	kappa	Homo.sapiens	Hu_IGKV1-33*01	98.5	Hu_IGKV1-33*01	75.0	L2	8	L2-8-1	4	SDASNMET	BLEABBBB
B	kappa	Homo.sapiens	Hu_IGKV1-33*01	98.5	Hu_IGKV1-33*01	100.0	L3	9	L3-9-cis7-1	7	QQYDNlPFT	BBAABBbBB
B	kappa	Homo.sapiens	Hu_IGKV1-33*01	98.5	Hu_IGKV1-33*01	100.0	L4	6	L4-6-1	9	GSGTDF	EBEABB
C	heavy	Homo.sapiens	Hu_IGHV3-30*02	97.3	Hu_IGHV3-30*02	92.3	H1	13	H1-13-1	9	AASGFTFNSYGMH	BBBLBBAAABBBB
C	heavy	Homo.sapiens	Hu_IGHV3-30*02	97.3	Hu_IGHV3-30*02	90.0	H2	10	H2-10-2	9	FIRYDGGNKY	BBBAALABBB
C	heavy	Homo.sapiens	Hu_IGHV3-30*02	97.3	Hu_IGHV3-30*02	50.0	H3	15	H3-15-*	-1	ANLKDSrYSGSYYDY
C	heavy	Homo.sapiens	Hu_IGHV3-30*02	97.3	Hu_IGHV3-30*02	100.0	H4	8	H4-8-1	11	RDNSKNTL	BBAAALBB
D	kappa	Homo.sapiens	Hu_IGKV3-20*01	97.1	Hu_IGKV3-20*01	100.0	L1	12	L1-12-1	5	RASQSVSsSYLA	BBABBBBAAABB
D	kappa	Homo.sapiens	Hu_IGKV3-20*01	97.1	Hu_IGKV3-20*01	100.0	L2	8	L2-8-1	8	YGASSRAT	BLLABBBB
D	kappa	Homo.sapiens	Hu_IGKV3-20*01	97.1	Hu_IGKV3-20*01	85.7	L3	9	L3-9-1	15	QQYGSSAWT	BBBELLBBB
D	kappa	Homo.sapiens	Hu_IGKV3-20*01	97.1	Hu_IGKV3-20*01	100.0	L4	6	L4-6-1	9	GSGTDF	EBEABB
E	heavy	Homo.sapiens	Hu_IGHV1-2*02	95.8	Hu_IGHV1-2*02	100.0	H1	13	H1-13-1	7	KASGYTFTGYYMH	BBBLBBAAABBBB
E	heavy	Homo.sapiens	Hu_IGHV1-2*02	95.8	Hu_IGHV1-2*02	70.0	H2	10	H2-10-1	8	WINPISSGTS	BBBAAALBBB
E	heavy	Homo.sapiens	Hu_IGHV1-2*02	95.8	Hu_IGHV1-2*02	100.0	H3	18	H3-18-*	-1	ARAAPFydfwSGYSYFDY
E	heavy	Homo.sapiens	Hu_IGHV1-2*02	95.8	Hu_IGHV1-2*02	75.0	H4	8	H4-8-1	10	SDTSITTA	BBAAALBB
G	kappa	Homo.sapiens	Hu_IGKV3-20*01	97.1	Hu_IGKV3-20*01	100.0	L1	12	L1-12-1	5	RASQSVSsSYLA	BBABBBBAAABB
G	kappa	Homo.sapiens	Hu_IGKV3-20*01	97.1	Hu_IGKV3-20*01	100.0	L2	8	L2-8-1	8	YGASSRAT	BLLABBBB
G	kappa	Homo.sapiens	Hu_IGKV3-20*01	97.1	Hu_IGKV3-20*01	85.7	L3	9	L3-9-1	15	QQYGSSAWT	BBBELLBBB
G	kappa	Homo.sapiens	Hu_IGKV3-20*01	97.1	Hu_IGKV3-20*01	100.0	L4	6	L4-6-1	9	GSGTDF	EBEABB
H	heavy	Homo.sapiens	Hu_IGHV1-2*02	95.8	Hu_IGHV1-2*02	100.0	H1	13	H1-13-1	7	KASGYTFTGYYMH	BBBLBBAAABBBB
H	heavy	Homo.sapiens	Hu_IGHV1-2*02	95.8	Hu_IGHV1-2*02	70.0	H2	10	H2-10-1	8	WINPISSGTS	BBBAAALBBB
H	heavy	Homo.sapiens	Hu_IGHV1-2*02	95.8	Hu_IGHV1-2*02	100.0	H3	18	H3-18-*	-1	ARAAPFydfwSGYSYFDY
H	heavy	Homo.sapiens	Hu_IGHV1-2*02	95.8	Hu_IGHV1-2*02	75.0	H4	8	H4-8-1	10	SDTSITTA	BBAAALBB
I	kappa	Homo.sapiens	Hu_IGKV1-33*01	98.5	Hu_IGKV1-33*01	81.8	L1	11	L1-11-1	8	QASQDIRFYLN	BBABBAEABBB
I	kappa	Homo.sapiens	Hu_IGKV1-33*01	98.5	Hu_IGKV1-33*01	75.0	L2	8	L2-8-1	4	SDASNMET	BLEABBBB
I	kappa	Homo.sapiens	Hu_IGKV1-33*01	98.5	Hu_IGKV1-33*01	100.0	L3	9	L3-9-cis7-1	7	QQYDNlPFT	BBAABBbBB
I	kappa	Homo.sapiens	Hu_IGKV1-33*01	98.5	Hu_IGKV1-33*01	100.0	L4	6	L4-6-1	9	GSGTDF	EBEABB
J	heavy	Homo.sapiens	Hu_IGHV3-30*02	97.3	Hu_IGHV3-30*02	92.3	H1	13	H1-13-1	9	AASGFTFNSYGMH	BBBLBBAAABBBB
J	heavy	Homo.sapiens	Hu_IGHV3-30*02	97.3	Hu_IGHV3-30*02	90.0	H2	10	H2-10-2	9	FIRYDGGNKY	BBBAALABBB
J	heavy	Homo.sapiens	Hu_IGHV3-30*02	97.3	Hu_IGHV3-30*02	50.0	H3	15	H3-15-*	-1	ANLKDSrYSGSYYDY
J	heavy	Homo.sapiens	Hu_IGHV3-30*02	97.3	Hu_IGHV3-30*02	100.0	H4	8	H4-8-1	11	RDNSKNTL	BBAAALBB
L	kappa	Homo.sapiens	Hu_IGKV3-20*01	97.1	Hu_IGKV3-20*01	100.0	L1	12	L1-12-1	5	RASQSVSsSYLA	BBABBBBAAABB
L	kappa	Homo.sapiens	Hu_IGKV3-20*01	97.1	Hu_IGKV3-20*01	100.0	L2	8	L2-8-1	8	YGASSRAT	BLLABBBB
L	kappa	Homo.sapiens	Hu_IGKV3-20*01	97.1	Hu_IGKV3-20*01	85.7	L3	9	L3-9-1	15	QQYGSSAWT	BBBELLBBB
L	kappa	Homo.sapiens	Hu_IGKV3-20*01	97.1	Hu_IGKV3-20*01	100.0	L4	6	L4-6-1	9	GSGTDF	EBEABB
M	heavy	Homo.sapiens	Hu_IGHV1-2*02	95.8	Hu_IGHV1-2*02	100.0	H1	13	H1-13-1	7	KASGYTFTGYYMH	BBBLBBAAABBBB
M	heavy	Homo.sapiens	Hu_IGHV1-2*02	95.8	Hu_IGHV1-2*02	70.0	H2	10	H2-10-1	8	WINPISSGTS	BBBAAALBBB
M	heavy	Homo.sapiens	Hu_IGHV1-2*02	95.8	Hu_IGHV1-2*02	100.0	H3	18	H3-18-*	-1	ARAAPFydfwSGYSYFDY
M	heavy	Homo.sapiens	Hu_IGHV1-2*02	95.8	Hu_IGHV1-2*02	75.0	H4	8	H4-8-1	10	SDTSITTA	BBAAALBB
N	kappa	Homo.sapiens	Hu_IGKV1-33*01	98.5	Hu_IGKV1-33*01	81.8	L1	11	L1-11-1	8	QASQDIRFYLN	BBABBAEABBB
N	kappa	Homo.sapiens	Hu_IGKV1-33*01	98.5	Hu_IGKV1-33*01	75.0	L2	8	L2-8-1	4	SDASNMET	BLEABBBB
N	kappa	Homo.sapiens	Hu_IGKV1-33*01	98.5	Hu_IGKV1-33*01	100.0	L3	9	L3-9-cis7-1	7	QQYDNlPFT	BBAABBbBB
N	kappa	Homo.sapiens	Hu_IGKV1-33*01	98.5	Hu_IGKV1-33*01	100.0	L4	6	L4-6-1	9	GSGTDF	EBEABB
O	heavy	Homo.sapiens	Hu_IGHV3-30*02	97.3	Hu_IGHV3-30*02	92.3	H1	13	H1-13-1	9	AASGFTFNSYGMH	BBBLBBAAABBBB
O	heavy	Homo.sapiens	Hu_IGHV3-30*02	97.3	Hu_IGHV3-30*02	90.0	H2	10	H2-10-2	9	FIRYDGGNKY	BBBAALABBB
O	heavy	Homo.sapiens	Hu_IGHV3-30*02	97.3	Hu_IGHV3-30*02	50.0	H3	15	H3-15-*	-1	ANLKDSrYSGSYYDY
O	heavy	Homo.sapiens	Hu_IGHV3-30*02	97.3	Hu_IGHV3-30*02	100.0	H4	8	H4-8-1	11	RDNSKNTL	BBAAALBB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022