PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 7MW6

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
D	heavy	Homo.sapiens	Mo_IGHV1-42*01	97.3	Mo_IGHV1-42*01	92.3	H1	13	H1-13-*	-1	KASGYSFTGYSMN	BAEABALAABBBB
D	heavy	Homo.sapiens	Mo_IGHV1-42*01	97.3	Mo_IGHV1-42*01	100.0	H2	10	H2-10-1	20	EINPSTGGTT	BBBAAALBBB
D	heavy	Homo.sapiens	Mo_IGHV1-42*01	97.3	Mo_IGHV1-42*01	100.0	H3	7	H3-7-*	-1	ARSRGDY	BBEALAB
D	heavy	Homo.sapiens	Mo_IGHV1-42*01	97.3	Mo_IGHV1-42*01	100.0	H4	8	H4-8-1	14	VDKSSSTA	BBAAALBB
E	kappa	Homo.sapiens	Mo_IGKV3-1*01	98.6	Mo_IGKV3-1*01	100.0	L1	15	L1-15-1	16	RASESVEYYgtslMQ	BBABBABBLLBBBBB
E	kappa	Homo.sapiens	Mo_IGKV3-1*01	98.6	Mo_IGKV3-1*01	100.0	L2	8	L2-8-*	-1	YAASNVES	ABAABBBB
E	kappa	Homo.sapiens	Mo_IGKV3-1*01	98.6	Mo_IGKV3-1*01	100.0	L3	9	L3-9-2	21	QQSRKVPWT	BBAABABBB
E	kappa	Homo.sapiens	Mo_IGKV3-1*01	98.6	Mo_IGKV3-1*01	100.0	L4	6	L4-6-1	20	GSGTDF	EBEABB
F	heavy	Homo.sapiens	Mo_IGHV1-42*01	97.3	Mo_IGHV1-42*01	92.3	H1	13	H1-13-*	-1	KASGYSFTGYSMN	BAEABALAABBBB
F	heavy	Homo.sapiens	Mo_IGHV1-42*01	97.3	Mo_IGHV1-42*01	100.0	H2	10	H2-10-1	17	EINPSTGGTT	BBBAAALBBB
F	heavy	Homo.sapiens	Mo_IGHV1-42*01	97.3	Mo_IGHV1-42*01	100.0	H3	7	H3-7-*	-1	ARSRGDY	BBEALAB
F	heavy	Homo.sapiens	Mo_IGHV1-42*01	97.3	Mo_IGHV1-42*01	100.0	H4	8	H4-8-1	13	VDKSSSTA	BBAAALBB
G	kappa	Homo.sapiens	Mo_IGKV3-1*01	98.6	Mo_IGKV3-1*01	100.0	L1	15	L1-15-1	16	RASESVEYYgtslMQ	BBABBABBLLBBABB
G	kappa	Homo.sapiens	Mo_IGKV3-1*01	98.6	Mo_IGKV3-1*01	100.0	L2	8	L2-8-*	-1	YAASNVES	ABAABBBB
G	kappa	Homo.sapiens	Mo_IGKV3-1*01	98.6	Mo_IGKV3-1*01	100.0	L3	9	L3-9-2	21	QQSRKVPWT	BBAABABBB
G	kappa	Homo.sapiens	Mo_IGKV3-1*01	98.6	Mo_IGKV3-1*01	100.0	L4	6	L4-6-1	19	GSGTDF	EBEABB
H	heavy	Homo.sapiens	Mo_IGHV1-42*01	97.3	Mo_IGHV1-42*01	92.3	H1	13	H1-13-*	-1	KASGYSFTGYSMN	BAEABALAABBBB
H	heavy	Homo.sapiens	Mo_IGHV1-42*01	97.3	Mo_IGHV1-42*01	100.0	H2	10	H2-10-1	21	EINPSTGGTT	BBBAAALBBB
H	heavy	Homo.sapiens	Mo_IGHV1-42*01	97.3	Mo_IGHV1-42*01	100.0	H3	7	H3-7-*	-1	ARSRGDY	BBEALAB
H	heavy	Homo.sapiens	Mo_IGHV1-42*01	97.3	Mo_IGHV1-42*01	100.0	H4	8	H4-8-1	14	VDKSSSTA	BBAAALBB
L	kappa	Homo.sapiens	Mo_IGKV3-1*01	98.6	Mo_IGKV3-1*01	100.0	L1	15	L1-15-1	13	RASESVEYYgtslMQ	BBABBABBLLBBABB
L	kappa	Homo.sapiens	Mo_IGKV3-1*01	98.6	Mo_IGKV3-1*01	100.0	L2	8	L2-8-*	-1	YAASNVES	ABAABBBB
L	kappa	Homo.sapiens	Mo_IGKV3-1*01	98.6	Mo_IGKV3-1*01	100.0	L3	9	L3-9-2	19	QQSRKVPWT	BBAABABBB
L	kappa	Homo.sapiens	Mo_IGKV3-1*01	98.6	Mo_IGKV3-1*01	100.0	L4	6	L4-6-1	15	GSGTDF	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022